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| Number | Title | Issue Date |
| 8173651 | Pyridine compounds This invention features compounds of formula (I): pharmaceutical compositions of the compounds, and methods of using the compounds for the treatment of, inter alia, IL-12-related diseases and disorders. ... | 05/08/2012 |
| 8158169 | Chinese medicine composition and preparation method and use thereof This invention relates a traditional Chinese medicine composition and the drug containing this composition as well as preparation method and use thereof. The composition comprises 1-10 parts by weight of radix ginseng, 1-10 parts by weight of folium ginkgo, 0.05-0.5... | 04/17/2012 |
| 8153146 | Pesticide and fungicide treatments made from hop extracts The invention is an organic pesticide or fungicide made from components of hop extract by preparing stable aqueous emulsions of hop acids and other hop extract components. The hop acids and other hop extract components are suspended as stable, colloidal preparations... | 04/10/2012 |
| 8143294 | 2-sulfanyl-substituted imidazole derivatives and their use as cytokine inhibitors The invention relates to 2-thio-substituted imidazole derivatives of the Formula I, and to methods of use thereof. ... | 03/27/2012 |
| 8142821 | Xanthohumol-enriched hop extract A method for preparing a xanthohumol-rich hop composition. The method includes providing a solution that contains xanthohumol-containing hop substances and effecting precipitation of non-xanthohumol hop substances by adjusting both the salt concentration and pH valu... | 03/27/2012 |
| 8142820 | Methods for treating or preventing infestation The present invention provides methods and compositions for controlling a fungal or insect infestation. ... | 03/27/2012 |
| 8138333 | Sulfonyl-indole derivatives The present invention relates to novel compounds of formula (I): wherein R1, R2, R3, R4, and R5 are as described herein, to pharmaceutical comp... | 03/20/2012 |
| 8129418 | Macrocyclic compounds and methods of treatment The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation. ... | 03/06/2012 |
| 8119071 | Apparatus for the generation of chlorine dioxide The instant application provides apparatus and methods for the generation of chlorine dioxide. The methods and apparatus of the invention use a water dissolvable membrane to allow the reaction of precursor chemicals, e.g., chlorite salt and an acid. The methods and ... | 02/21/2012 |
| D651508 | Sealable container assembly | 01/03/2012 |
| 8039470 | Kinase inhibitor compounds The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes... | 10/18/2011 |
| 8034837 | Polymorphic form of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizin-5-ylacetic acid The present invention relates to a new crystalline modification of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,S-dihydro-1H-pyrrolizin-S-ylacetic acid which is referred to as polymorph B. It has a peak in the solid state 13C-NMR spectrum (with adamantane a... | 10/11/2011 |
| 8033283 | Urology drape A urology drape is disclosed which comprises a flexible sheet (12) which has a flexible hood (22) overlying part of the sheet (12) to form a repository (24) between the sheet (12) and the hood (22). The sheet (12) has... | 10/11/2011 |
| 8003646 | Substituted triazolo-pyridazine derivatives This invention relates to novel substituted triazolo-pyridazines, their derivatives, and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treat... | 08/23/2011 |
| 8003613 | Methods and compositions for inducing apoptosis The C-terminal domain of focal adhesion kinase (FAK-CD) was isolated using a Baculoviral system. Using phage display techniques, a phage encoding a 12 amino-acid peptide (peptide 35) and AV3 that binds to FAK-CD were identified. The peptides were also conjugated to ... | 08/23/2011 |
| 7960374 | Tricyclic compounds, compositions, and methods useful in the treatment or prophylaxis of 5-HTreceptor-related disorders The present invention relates to compounds of the formula (I) wherein A, X and R1 to R9 are as described herein; to pharmaceutical compositions comprising the said compounds; to processes for their pre... | 06/14/2011 |
| 7956045 | Compositions and methods for animal treatment A method of improving the health and production of ruminant animals, the method including the step of orally administering to the animal an effective amount of an indigestible oligosaccharide selected from the group of gluco-oligosaccharides and isomalto-oligosaccha... | 06/07/2011 |
| 7935698 | Heteroaryl-hydrazone compounds This invention relates to compounds having a formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, hydrate, prodrug or polymorph thereof wherein X is —C(Rg)═N-A. The invention also relates t... | 05/03/2011 |
| 7932235 | Triazolyl tropane derivatives This invention relates to novel triazolyl tropane derivatives, their acceptable acid addition salts, solvates, hydrates and polymorphs thereof. The invention also provides compositions comprising a compound of this invention and the use of such compositions in metho... | 04/26/2011 |
| 7923557 | Process for preparing trisubstituted pyrimidine compounds Disclosed herein is a regioselective synthesis of compounds represented by formula (I): or a salt, solvate, clathrate, or prodrug thereof, wherein X, Y, R2, R3, R4, R7, R8 | 04/12/2011 |
| 7919487 | Heteroaryl compounds This invention relates to compounds of formula (I): their compositions and methods of use thereof. The compounds (and compositions) are useful in modulating IL-12 production and processes mediated by IL-12. ... | 04/05/2011 |
| 7919270 | Mammalian expression system The present invention relates to protein expression systems and in particular to a mammalian protein expression system. Specifically, the present invention provides a rodent cell line with enhanced protein production capabilities. The invention also relates t... | 04/05/2011 |
| 7906513 | Hydrazide-containing hepatitis C serine protease inhibitors The present invention relates to novel hydrazide-containing compounds of Formula I or Formula II, including pharmaceutically acceptable salts, esters, or prodrugs thereof which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS... | 03/15/2011 |
| 7888088 | Superoxide dismutase (SOD) gene and a method of identifying and cloning thereof The present invention provides a superoxide dismutase gene from Potentilla atrosanguinea, a construct containing the gene coding for superoxide dismutase and transformed E. coli producing the SOD protein. ... | 02/15/2011 |
| 7872005 | 2-substituted heteroaryl compounds This invention relates to compounds of formula (I): or pharmaceutically acceptable salts, solvate, clathrates hydrates or polymorphs thereof, their compositions and methods of use and methods of making thereof. The compound... | 01/18/2011 |
| 7863274 | Deuterium enriched analogues of tadalafil as PDE5 inhibitors The present invention relates to derivatives of tadalafil represented by the formula: or a salt thereof, wherein: X1 and X2 are simultaneously fluoro; or X1 | 01/04/2011 |
| 7863270 | IL-12 modulatory compounds The invention relates to cyclic hydrazone compounds and compositions including the cyclic hydrazone compounds according to formula (I): The compounds (and compositions) are useful, inter alia, in modulating IL-12 production... | 01/04/2011 |
| 7855204 | Derivatives of gefitinib This invention relates to novel quinazoline derivatives, their derivatives, pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases ... | 12/21/2010 |
| 7851466 | Pyrimidine compounds and uses thereof This invention features pyrimidine compounds of formula (I): aryl, or heteroaryl; each of R2 and R4, independently, is Rc, halogen, nitro, cyano, isothionit... | 12/14/2010 |
| 7833552 | Xanthohumol-enriched hop extract A method for preparing a xanthohumol-rich hop composition. The method includes providing a solution that contains xanthohumol-containing hop substances and effecting precipitation of non-xanthohumol hop substances by adjusting both the salt concentration and pH valu... | 11/16/2010 |
| 7820811 | Pro-drugs of adenosine receptor agonists The invention relates to a method of improving oral drug absorption of adenosine analogues by the use of 2′-methoxy adenosine pro-drugs and to the use of these pro-drugs as medicaments. The invention further relates to compounds that are pro-drugs of adenosine rec... | 10/26/2010 |
| 7820256 | Stirring rod The invention relates to a rod, particularly a stirring rod for liquids, said stirring rod comprising a hollow structure, which is made of transparent material and the interior of which is filled with liquid and/or gas, and in which is present at least one solid bod... | 10/26/2010 |
| 7819021 | Fluid meter The invention relates to a fluid meter (1) having a measuring tube housing (2), a measuring zone (3) inside the measuring tube housing (2), an ultrasonic transducer configuration of at least one ultrasonic transducer (4 and/or 5... | 10/26/2010 |
| 7799539 | Apparatus for detecting and recording cellular responses Cellular physiology workstations for automated data acquisition and perfusion control are described. The cellular physiology workstation may be used for physiological and electrophysiological experiments. Methods for employing such cellular physiology workstations i... | 09/21/2010 |
| 7767969 | Method and apparatus for measuring spectroscopic absorbance An object of the present invention is to provide a spectroscopic method and an apparatus which can measure a trace element accurately with high sensitivity. In order to achieve this object, for example, in Fourier transformation infrared spectroscopy (FT-IR), a refe... | 08/03/2010 |
| 7767797 | Macrocyclic compounds and methods of use thereof The invention features novel macrocyclic compounds, methods of making the compounds, pharmaceutical compositions including the compounds, and methods of treatment using the compounds. ... | 08/03/2010 |
| 7759514 | Mu opioid receptor ligands: methods of use and synthesis Novel compounds and compositions including those compounds, as well as methods of using and making the compounds are herein described. The compounds are useful in therapeutic applications, including modulation of disease or disease symptoms in a subject (e.g., mamma... | 07/20/2010 |
| 7745436 | Disalt inhibitors of IL-12 production This invention relates to disalt nitrogen-heteroaryl inhibitors of IL-12 production, and related methods and pharmaceutical compositions. ... | 06/29/2010 |
| 7723255 | Recyclable metathesis catalysts Highly active, recoverable and recyclable transition metal-based metathesis catalysts and their organometallic complexes including dendrimeric complexes are disclosed, including a Ru complex bearing a 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene and styrenyl ether li... | 05/25/2010 |
| 7722780 | Refrigerant composition and process for preparation thereof The present application provides a refrigerant composition for a single stage refrigeration system operation comprising: more than 25 molar percent but less than 30 molar percent of Nitrogen; at least some but less than 20 molar percent of Methane; more than 30 mola... | 05/25/2010 |
