...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 8126649 | Methods for generating a distribution of optimal solutions to nondeterministic polynomial optimization problems The present invention provides methods for generating a distribution of optimal answers to a nondeterministic polynomial optimization problem by providing a plurality of solutions comprising input polynucleotides, wherein each solution comprises identical input poly... | 02/28/2012 |
| 8071657 | Organic, open cell foam materials, their carbonized derivatives, and methods for producing same Organic, small pore area materials (“SPMs”) are provided comprising open cell foams in unlimited sizes and shapes. These SPMs exhibit minimal shrinkage and cracking. Processes for preparing SPMs are also provided that do not require supercritical extraction. The... | 12/06/2011 |
| 7531570 | Treatment of diseases using ICE inhibitors This invention relates to methods and compositions for treating autoinflammatory diseases. The invention also assays for evaluating the ability of an ICE inhibitor to treat autoinflammatory diseases. ... | 05/12/2009 |
| 7521485 | Organic, open cell foam materials, their carbonized derivatives, and methods for producing same Organic, small pore area materials (“SPMs”) are provided comprising open cell foams in unlimited sizes and shapes. These SPMs exhibit minimal shrinkage and cracking. Processes for preparing SPMs are also provided that do not require supercritical extraction. The... | 04/21/2009 |
| 7498289 | Ni catalysts and methods for alkane dehydrogenation Catalysts and methods for alkane oxydehydrogenation are disclosed. The catalysts of the invention generally comprise (i) nickel or a nickel-containing compound and (ii) at least one or more of titanium (Ti), tantalum (Ta), niobium (Nb), hafnium (Hf), tungsten (W), y... | 03/03/2009 |
| 7410956 | Caspase inhibitor prodrugs The present invention relates to compounds of formula I which are prodrugs of caspase inhibitors and pharmaceutically acceptable salts thereof. This invention further relates to the release of caspase inhibitors from these compounds through selective bond cleavage. ... | 08/12/2008 |
| 7358273 | Inhibitors of caspases The present invention relates to novel classes of compounds which are caspase inhibitors, in particular interleukin-1β converting enzyme (“ICE”) inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and... | 04/15/2008 |
| 7227049 | Ni catalysts and methods for alkane dehydrogenation Catalysts and methods for alkane oxydehydrogenation are disclosed. The catalysts of the invention generally comprise (i) nickel or a nickel-containing compound and (ii) at least one or more of titanium (Ti), tantalum (Ta), niobium (Nb), hafnium (Hf), tungsten (W), y... | 06/05/2007 |
| 7226603 | HBV core antigen particles with multiple immunogenic components attached via peptide ligands This invention relates to hepatitis B virus (“HBV”) core antigen particles that are characterized by multiple immunogen specificities. More particularly, the invention relates to HBV core antigen particles comprising immunogens, epitopes, or other related struct... | 06/05/2007 |
| 7005181 | Organic, open cell foam materials, their carbonized derivatives, and methods for producing same Organic, small pore area materials (“SPMs”) are provided comprising open cell foams in unlimited sizes and shapes. These SPMs exhibit minimal shrinkage and cracking. Processes for preparing SPMs are also provided that do not require supercritical extraction. The... | 02/28/2006 |
| 6962996 | Inhibitors of p38 The present invention relates to inhibitors of p38, a mammalian protein kinase involved cell proliferation, cell death and response to extracellular stimuli. The invention also relates to methods for producing these inhibitors. The invention also provides pharmaceut... | 11/08/2005 |
| 6800626 | Inhibitors of p38 The present invention relates to inhibitors of p38, a mammalian protein kinase involved in cell proliferation, cell death and response to extracellular stimuli. The invention relates to compounds having the formula: or p... | 10/05/2004 |
| 6666752 | Wafer retainer and method for attaching/detaching the wafer retainer to/from polishing machine base plate A wafer retainer includes: a foam layer capable of adsorbing a wafer on a surface thereof in a detachable manner; a first pressure-sensitive adhesive layer formed on a back face of the foam layer; a support formed on a back face of the first pressure-sens... | 12/23/2003 |
| 6616520 | Polishing cloth and method for attaching/detaching the polishing cloth to/from polishing machine base plate A polishing cloth includes: a polishing cloth substrate; a first-pressure adhesive layer formed on a back face of the polishing cloth substrate; as support formed on a back face of the first pressure-sensitive adhesive layer; a second pressure-sensitive a... | 09/09/2003 |