Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 4871546 | Gastrointestinal protective coating formulations Tablet formulations for the diffusable release of drugs in the gastrointestinal tract, which formulations protect the gastric mucosa from the effects of solid, gastric irritating drugs. The formulation comprises a drug tablet core, coated with a water per... | 10/03/1989 |
| 4868319 | Process for the preparation of monoalkylcarbamate group-containing compounds An improved process for preparing monoalkylcarbamate group-containing compounds comprising reacting a hydroxy group-containing compound with an organic halide and an alkali metal cyanate in the conjoint presence of a phase transfer catalyst and a solvent.... | 09/19/1989 |
| 4855306 | Uses of dopamine receptor agonists Selective dopamine D1 receptor agonists for use in the treatment of primary degenerative dementia, depression, anxiety, obesity or schizophrenia.... | 08/08/1989 |
| 4855288 | Furanuronic acid derivatives, process for their production and their use 1'-desoxy-1'-(6-amino-9-purinyl)-ଲ-D-ribofuranuronic acid thioamides of formula ##STR1## wherein R1, R2 and R3 possess various definitions given in claim 2, are effective against raised blood pressure.... | 08/08/1989 |
| 4855075 | Ethoxylates of alkyl and alkenyl catechols The invention relates to novel ethoxylates of alkyl and alkenyl catechols and to their use as surface active agents. The novel ethoxylates of alkyl and alkenyl catechols are especially useful as self-sequestering surfactants in detergent compositions.... | 08/08/1989 |
| 4849423 | Purine derivatives, medicaments containing them and methods of treating cardiac insufficiencies and irregularities with them. The compounds of formula I, ##STR1## in free form or in salt form have cardiotonic and antiarrhythmic activity. They may be used as medicaments. They are obtained by means of appropriate 3-amino-2-hydroxy-propylation of purines.... | 07/18/1989 |
| 4847296 | Triglyceride preparations for the prevention of catabolism Chemically synthesized structured triglycerides (lipids) for enteral administration as the lipid calorie source, is subjects undergoing severe metabolic stress.... | 07/11/1989 |
| 4847384 | Process for the preparation of certain nitrogen-containing mono- and bicyclic ace inhibitors, and novel intermediates useful therefor An improved process for preparing certain nitrogen-containing mono- and bicyclic ACE inhibitors comprising reacting an -alkyl amino acid with a disulfide compound to form a thioester intermediate, which intermediate is then amidated with a mono- or... | 07/11/1989 |
| 4845129 | Diaryl substituted cyclopentane and cyclopentene derivatives The invention discloses certain diaryl substituted cyclopentane and cyclopentene derivatives useful as PAF inhibitors, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method of using such compositions for inhibi... | 07/04/1989 |
| 4835174 | Pilocarpine derivatives Pilocarpine derivatives of formula I, ##STR1## wherein R1 to R5 are as defined in the description, are useful in the treatment of senile dementia, Alzheimer's disease, confusional conditions in the elderly, myasthenia gravis, sc... | 05/30/1989 |
| 4826838 | Analgesic carbocyclic and heterocyclic carbonylmethylene-and carbonylmethypipidines and-pyrrolidines Carbocyclic and heterocyclic carbonylmethylene- and carbonylmethylpiperidines and -pyrrolidines are serotonin antagonists.... | 05/02/1989 |
| 4826972 | Method for preparing crystalline cephalosporin derivative The invention provides crystalline (6R, 7R)-7-[[2-(2-Amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methyle thoxy)imino ]acetamido]-3-(1-pyridiniummethyl)-3-cephem-4-carboxylate and a process for its production.... | 05/02/1989 |
| 4824950 | Chiral stationary phases and columns for chromatographic resolution This invention relates to chiral compositions.... | 04/25/1989 |
| 4820718 | N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furanyl)-substituted cyclimmonium salts and use thereof in PAF inhibition The invention discloses certain N-alkyl-(2- or 5-substituted-2-methoxycarbonyl aminoalkyl furanyl)-substituted cyclimmonium salts useful as PAF inhibitors, pharmaceutical compositions containing said compounds as an active ingredient thereof and a method ... | 04/11/1989 |
| 4804660 | Ergot cyclic peptide alkaloids having a venotonizing effect, useful for treating orthostatic hypotension 9-thia ergot cyclic peptide alkaloids produced by fermentation or synthetic methods have interesting anti-parkinson and other pharmacological activities.... | 02/14/1989 |
| 4803199 | Pharmaceutically useful heterocyclic and carbocyclic acid esters and amides of alkylene bridged piperidines The dicarboxylic, heterocyclic and substituted benzoic acid alkylene bridged piperidyl amides and esters are serotonin M antagonists.... | 02/07/1989 |
| 4801739 | Oligomeric hydroxycarboxylic acid derivatives, their production and use A product of an oligomer derived from glycolic acid and/or lactic acid, the oligomer having a molecular weight of from 500 to 10,000, the free carboxylic acid group of the oligomer being at least partially in the form of an amide with an amino acid or an ... | 01/31/1989 |
| 4801457 | Polyacetal hydrogels formed from divinyl ethers and polyols A therapeutic composition comprising a therapeutic macromolecular agent incorporated in cross-linked polyacetal.... | 01/31/1989 |
| 4800204 | Method of controlling tobacco use The control of tobacco use in humans with a direct dopamine receptor agonist.... | 01/24/1989 |
| 4797404 | Pharmaceutical preparation comprising co-dergocrine and a calcium antagonist Pharmaceutical preparations comprising (a) co-dergocrine or a pharmaceutically acceptable acid addition salt thereof and (b) a calcium antagonist or a pharmaceutically acceptable salt thereof, as well as the treatment of hypertension/migraine by co-admini... | 01/10/1989 |
| 4797406 | Amides and esters containing bridged piperidines and use as serotonin M antagonists The dicarboxylic, heterocyclic and substituted benzoic acid alkylene bridged piperidyl amides and esters are serotonin M antagonists.... | 01/10/1989 |
| 4795759 | Use of dibenz(CD,F)indoles 4,5,5a,6-tetrahydro-dibenz[cd,f]indole derivatives having at least one oxy substitutent in one or both of the fused benzene rings, for the prevention of alcohol abuse.... | 01/03/1989 |
| 4792598 | Poly-dicaboxylic acid anhydrides and polymeric anhydrides therefrom New poly-dicarboxylic acid anhydrides, which are suitable as bio-degradable matrix materials for the controlled release of medicinal agents in humans. The anhydrides have the following formula: ##STR1## where ##STR2## where n=an integer of ... | 12/20/1988 |
| 4791116 | N,N-diethyl-N'-[(8)-1-ethyl-6-methyl-ergolin-8-yl]-sulfamide useful as prolactin secretion inhibitor, anti-parkinson agents and anti-depressant agents The present invention provides N,N-Diethyl-N'-[(8)-1-ethyl-6-methyl-ergolin-8-yl]-sulfamide, and N,N-Diethyl-N'-[(8)-1-isopropyl-6-methyl-ergolin-8-yl)-sulfamide useful as prolactin secretion inhibiton, anti-parkinson agents and anti-de... | 12/13/1988 |
| 4791115 | 2,6-dimethyl-8-pivaloylamino-9,10-didehydro-ergoline Compounds of formula I ##STR1## wherein R1 is hydrogen or C1-4 alkyl, R2 is hydrogen, chlorine, bromine or methyl, R3 is C1-5 alkyl or C3-5 alkenyl and R4 is C1-7... | 12/13/1988 |
| 4789673 | Heterocyclic carboxylic acid amides and esters The dicarboxylic, heterocyclic and substituted benzoic acid alkylene bridged piperidyl amides and esters are serotonin M antagonists.... | 12/06/1988 |
| 4786410 | Fluid treatment apparatus with semi-permeable membranes, useful as a haemodialyser The invention relates to a fluid treatment apparatus resulting from the stacking of plates 1 each having, on each of their two main faces, a treatment zone 3 provided with ribs 2, the two membranes being placed between the opposite faces of each adjacent ... | 11/22/1988 |
| 4786411 | Fluid treatment apparatus with semi-permeable membranes The invention relates to an apparatus comprising a stack of plates having plates of a type A and a type B alternating. Each plate has exposed channels and a semi-permeable membrane 1 turned over one of its edges 2. The membranes extend into the exposed ch... | 11/22/1988 |
| 4783464 | N-substituted ergoline- and 9,10-didehydro-ergoline-8-carboxamide-and-8-aminomethyl-derivatives, their production and their pharmaceutical composition Novel N-substituted ergoline- and 9,10-didehydro-8-carboxamide- and -8-aminomethyl-derivatives for the treatment of vascular headaches, especially migraine, and of orthostatic hypotension.... | 11/08/1988 |
| 4780475 | Preparation for the prevention of catabolism Prevention of catabolism and increasing protein synthesis in a subject undergoing stress with compositions containing isoleucine, leucine and valine.... | 10/25/1988 |
| 4775691 | 4H-benzo[4,5]cyclohepta[1,2-b]thiophene derivatives [2-Halo-10-oxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]acetic acids, for example of formula I ##STR1## wherein R1 is H or C1-4 alkyl and R2 is halogen, their physiologically-hydrolysable and -acceptable ester... | 10/04/1988 |
| 4771122 | Novel cyclosporins Cylosporins e.g. of formula II ##STR1## in which X is -MeBmt- or -dihydro-MeBmt- and Y is -u-, -Thr-, -Val- or -Nva-, wherein the residue at the 3-position, i.e. the residue Z in formula II, is an optically active, -N-methylated -am... | 09/13/1988 |
| 4767526 | Artificial kidney with automatic regulation of the pressure of the dialyslate as a function of withdrawal of ultrafiltrate Artificial kidney comprises a hemodialyzer connected in a dialysis liquid circuit which is in the form of a loop the volume of which is essentially invariable. The circuit is open to the atmosphere and comprises a circulating pump arranged upstream of the... | 08/30/1988 |
| 4767852 | New process for producing cephalosporin antibiotics, and novel intermediates for use in such process and their production Process for the production of known 2-oximinoacetamido-3-cephem-4-carboxylic derivatives comprising acylation of 7-amino-3-cephem-4-carboxylic acid derivatives with novel 2-oximinoacetic acid thio esters, as well as such thioesters and their producti... | 08/30/1988 |
| 4765888 | Artificial kidney with integrated dialysate circuit An artificial kidney comprising a haemodialyser 16 connected to a dialysis liquid circuit. The latter can be entirely integrated, that is to say that the functions previously performed by a plurality of self-contained members connected to one another are ... | 08/23/1988 |
| 4766153 | Alkyl polyoxyalkylene carboxylate esters and skin care compositions containing the same The invention relates to novel alkyl polyoxyalkylene carboxylate esters and to their use as surface active agents. The novel esters are especially useful as emollients in skin care compositions.... | 08/23/1988 |
| 4764503 | Novel cyclosporins Cyclosporins wherein the amino acid residue at the 8-position is a (D)-acyloxy--amino acid residue, typically of formula ##STR1## wherein X=--MeBmt-- or --dihydro--MeBmt--, Y=--u--, --Ala--, --Thr--, --Val-- or --Nva--, Z=--Val-- or -... | 08/16/1988 |
| 4764517 | 8-(N,N-diethylsulfamoylamino)-6-n-propyl ergoline useful as a prolactin secretion inhibitor, anti-parkinson, anti-depressant agent A compound of formula I ##STR1## wherein R1 is n-propyl, R2 is hydrogen or alkyl(C1-3), R3 is alkyl(C1-3), and R4 is hydrogen or methyl in free base form or in pharmaceutically acceptable acid a... | 08/16/1988 |
| 4758423 | Certain ergot peptide alkaloids administered to the nasal mucosa The present invention provides a nasal pharmaceutical composition comprising as active agent a compound of formula I, ##STR1## wherein R1 is hydrogen or halogen, R2 is hydrogen or alkyl of 1 to 4 carbon atoms, either (i) R3 | 07/19/1988 |
| 4758550 | Calcitonin derivatives A compound of formula I ##STR1## wherein R is H or R'CO wherein R'CO is an acyl radical of a carboxylic acid, Y1 is the radical linked to an alpha carbon atom an -amino acid, Y2 is the radical linked to an alpha carbon at... | 07/19/1988 |
