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| Number | Title | Issue Date |
| 4868301 | Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains Oxophthalazinyl acetic acids having aldose reductase inhibitory properties of the formula ##STR1## wherein Z is hydrogen or methyl, U is S, CH2 or a covalent bond, and R1, R3, R4, R5 and R6 | 09/19/1989 |
| 4861779 | Anti-bacterial substituted bridged-diazabicycloalkyl quinolone carboxylic acids Antibacterial compounds have the formula ##STR1## wherein R1 is hydrogen, a pharmaceutically acceptable cation, or alkyl; A is CH, CF, CCl or N; Y is alkyl, haloalkyl, cyclopropyl, vinyl, methoxy, N-methylamino, p-fluorophenyl, p-hydroxyph... | 08/29/1989 |
| 4851130 | Oxygen removal with carbon catalyzed erythorbate or ascorbate When an aqueous system containing dissolved oxygen and erythorbate or ascorbate is passed through an activated carbon bed, the oxygen is removed at ambient temperatures. This method of oxygen removal finds practical application in the removal of oxygen fr... | 07/25/1989 |
| 4831031 | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity Arylpiperazinyl-ethyl(or butyl)-heterocyclic compounds and their pharmaceutically acceptable acid addition salts are neuroleptic agents. They are useful in the treatment of psychotic disorders.... | 05/16/1989 |
| 4797490 | Process for the preparation of 3-(2'-fluorophenyl)pyridine 6-Fluoro-7-pyridylquinolone carboxylic esters and acids having antibacterial activity are prepared by coupling of a 2-fluorophenyl-metallic compound with a pyridyl bromide or iodide in the presence of a transition metal catalyst, nitrating and hydrogenati... | 01/10/1989 |
| 4797403 | Quinazolinediones and pyridopyrimidinediones 1-Phenylquinazoline-1H,3H-2,4-diones and 1-phenylpyrido-[2,3d]-pyrimidine-1H,3H-2,4-diones, their esters and acid addition salts, and pharmaceutical compositions containing such compounds have antidepressant, anti-inflammatory and analgesic activity.... | 01/10/1989 |
| 4775668 | Substituted bridged-diazabicycloalkyl quinolone carboxylic acids and anti-bacterial use thereof Antibacterial compounds have the formula ##STR1## wherein R1 is hydrogen, a pharmaceutically aceptable cation, or alkyl; A is CH, CF, CCl or N; Y is alkyl, haloalkyl, cyclopropyl, vinyl, methoxy, N-methylamino, p-fluorophenyl, p-hydroxyphe... | 10/04/1988 |
| 4772717 | Novel process for the preparation of biotin A novel process is described for preparation of biotin comprising preparation of substituted 3H, 5H-imidazo[1,5c]tetrahydro thiazoles by contacting the boron trifluoride adduct of an appropriate thiazoline with the metallic derivative of an ester enolate,... | 09/20/1988 |
| 4750482 | Hydrophilic, elastomeric, pressure-sensitive adhesive The present invention concerns a novel water-insoluble, hydrophilic, pressure-sensitive adhesive that has a number of unique characteristics including being elastomeric and ultraconformable. This adhesive includes an irradiation cross-linked synthetic org... | 06/14/1988 |
| 4748280 | Certain chlorination process for preparing 2-chloro-1,1,1-(C1 -C6 ) The 2-chloro-1,1,1-tri(C1 -C6)alkoxyethanes are prepared from the corresponding tri(C1 -C6)alkoxyethanes by chlorination with N-chlorosuccinimide or with chlorine in pyridine and a chlorohydrocarbon cosolvent.... | 05/31/1988 |
| 4732988 | Bicyclic precursors for the preparation of biotin A novel process is described for preparation of biotin comprising preparation of substituted 3H, 5H-imidazo[1, 5c]tetrahydro thiazoles by contacting the boron trifluoride adduct of an appropriate thiazoline with the metallic derivative of an ester enolate... | 03/22/1988 |
| 4723010 | Process for preparing chloromethyl thiazoles or oxazoles, and intermediates for use therein Chloromethyl group substituted heterocyclic compounds of the formulae ##STR1## wherein X is O or S; Y together with the two carbons to which Y is attached forms phenyl, pyridyl or pyrimidyl, each of which may be substituted by R; R is one of iodo or trifl... | 02/02/1988 |
| 4711888 | Hydroxy and alkoxy pyrimidines 2-Amino-4-substituted-5-(hydroxy or alkoxy)pyrimidines, which may be 6-substituted, and derivatives thereof are inhibitors of leukotriene synthesis and are therefore useful for the treatment of pulmonary, inflammatory, allergic and cardiovascular diseases... | 12/08/1987 |
| 4707281 | Drilling fluid additive containing high pyruvate xanthan A drilling fluid additive comprises high pyruvate xanthan and locust bean gum in a weight ratio of about 40:60 to 80:20. The additive increases the viscosity of the drilling fluid at low shear, has improved thermal stability, and increases the capacity of... | 11/17/1987 |
| 4699146 | Hydrophilic, elastomeric, pressure-sensitive adhesive The present invention concerns a novel water-insoluble, hydrophilic, pressure-sensitive adhesive that has a number of unique characteristics including being elastomeric and ultraconformable. This adhesive includes an irradiation cross-linked synthetic org... | 10/13/1987 |
| 4694087 | Imidazolidinone precursors for the preparation of biotin A novel process is described for preparation of biotin comprising preparation of substituted 3H, 5H-imidazo[1,5c]tetrahydro thiazoles by contacting the boron trifluoride adduct of an appropriate thiazoline with the metallic derivative of an ester enolate,... | 09/15/1987 |
| 4662939 | Process and composition for improved corrosion resistance Corrosion resistance of stainless steel powder moldings is improved by combining the powder before molding with about 8 to 16% by weight of an additive consisting essentially of about 2 to 30% by weight of tin and 98 to 70% by weight of copper and/or nick... | 05/05/1987 |
| 4636506 | 7-heterocyclic-1,4-dihydroquinolones 1-Alkyl-6,8-difluoro-7-heterocyclic-1,4-dihydroquinol-4-one 3-carboxylic acids having antibacterial activity are prepared by conventional cyclization methods.... | 01/13/1987 |
| 4631345 | Thiazole precursors for the preparation of biotin A novel process is described for preparation of biotin comprising preparation of substituted 3H, 5H-imidazo[1, 5c]tetrahydro thiazoles by contacting the boron triflouride adduct of an appropriate thiazoline with the metallic derivative of an ester enolate... | 12/23/1986 |
| 4627961 | Calcium-aluminum briquettes Calcium-aluminum briquettes comprising a mechanically compressed mixture of 65 to 80% by weight of calcium granules and 20 to 35% by weight of aluminum granules are added to molten lead to obtain a lead alloy containing about 0.1% by weight of calcium and... | 12/09/1986 |
| 4624256 | Caprolactone polymers for suture coating High molecular weight caprolactone polymers are coated on surgical sutures to improve suture properties such as smooth surface, single knot slipdown, two throw knot slipdown for repositioning, and three throw knot security.... | 11/25/1986 |
| 4623650 | Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids 1-Substituted-6-fluoro-7-aryl-(8-fluoro)-1,4-dihydroquinol-4-one 3-carboxylic acids having antibacterial activity are prepared by reacting the corresponding alkyl 1-substituted-6-fluoro-7-bromo-(8-fluoro)-1,4-dihydroquinol-4-one-3-carbox ylate with an... | 11/18/1986 |
| 4621638 | Hard elastic sutures A surgical suture made of a polymer filament having the "hard" elastic properties of reversible elasticity and retention of diameter on stretching.... | 11/11/1986 |
| 4613516 | Bonding of bioactive glass coatings The adherence of a bioactive glass coating to a metal substrate is improved by applying said glass to said substrate in admixture with at least one of cobaltic oxide, cobaltous oxide, nickel oxide or manganese oxide, and firing the coated substrate at at ... | 09/23/1986 |
| 4598859 | Exhausting gas from a metal assembly Gases entrapped in a metal assembly are exhausted through a vent closed off by a metal or metal alloy which has a melting point below the temperature at which said assembly is hot rolled. The metal assembly is designed to bond dissimilar metals on hot rol... | 07/08/1986 |
| 4581459 | Process for the preparation of biotin A novel process is described for preparation of biotin comprising preparation of substituted 3H, 5H-imidazo[1, 5c]tetrahydro thiazoles by contacting the boron trifluoride adduct of an appropriate thiazoline with the metallic derivative of an ester enolate... | 04/08/1986 |
| 4489075 | Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants 6,7-Dialkoxy-4-[4-(cyclic-sulfonamidoalkyl)piperidino]quinazolines and method of use as cardiac stimulants.... | 12/18/1984 |
