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Attorney: Hoch; James M., Baran; Robert J., Voet; Martin A.


Number of patents: 7
Last date: April 06, 1999

NumberTitleIssue Date
5891911Method for reducing intraocular pressure in the mammalian eye by administration of calcium chelators
Pharmaceutical compositions and a method are disclosed for treating glaucoma and/or ocular hypertension in the mammalian eye by administering to the mammalian eye the pharmaceutical composition of the invention which contains as the active ingredient one ...
04/06/1999
5856329Method of using (2-imidazolin-2-ylamino) quinoxalines in treating ocular neural injury
A method according to which neuroprotection is conferred upon ocular nerve cells by administration of a drug of formula I to the optic nerve and/or retina of a mammal within a period prior to or following an insult to ocular nerve cells but prior to cell ...
01/05/1999
5731337Conformationally rigid bicycle and adamantane derivatives useful as ଱ 2
A compound of formula I ##STR1## in which: ring A is one of the five alternative multi-cyclic rings as shown wherein a dotted line adjacent to a bond indicates that a single bond or a double bond may be present at that position; X is nitrogen, o...
03/24/1998
5675038Lithium and amine dissolving metal reduction
The invention is directed to a process for reducing or reductively cleaving an organic compound susceptible to dissolving metal reduction comprising exposing the organic compound to a solution of lithium in a polyamine including at least two amino groups,...
10/07/1997
5521183Use of 5-HT ligands as anti-pruritic agents
The present invention is based on the finding that 5-HT receptor ligands are useful in treating experimental models of clinically encountered pruritus (itch). A 5-HT ligand as used in this specification is a compound capable of binding with some selectivi...
05/28/1996
5519040Substituted thiazole sulfonamides as antiglaucoma agents
The present invention provides novel carbonic anhydrase inhibitors represented by the structural formula: ##STR1## wherein...
05/21/1996
5420295Process for preparing 4,4-dialkyl-6-halo-chromans or thiochromans useful as pharmaceutical intermediates
A process of preparing intermediates useful in making compounds with retinoic acid-like activity is disclosed. The intermediates are halogenated chromans and thiochromans of the formula shown below and are prepared by the alkylation of a phenol or thiophe...
05/30/1995
 
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