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Patent No. 5593111

Safety System For Remove a Rider From a Vehicle by Deploying a Parachute

Methods and apparatus for reducing the velocity of a rider in or on an open cockpit vehicle when the rider is thrown from the vehicle.

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Attorney: Hobbs; Ann S.


Number of patents: 71
Last date: July 26, 2011

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NumberTitleIssue Date
7985766Combination of anticholineric and β mimetics for the treatment of respiratory diseases
The present invention describes a combination of an anticholinergic, such as R,R-glycopyrrolate, and a β mimetic, such as tormoterol, for the treatment of respiratory diseases including airway inflammation or obstruction such as chronic obstructive pulmonary diseas...
07/26/2011
7939557Vascular endothelial receptor specific inhibitors
The present application describes isoindoles and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful inhibitors of VEGFR. ...
05/10/2011
7887815Peptide diagnostic agent for lyme disease
The present invention relates, e.g., to an isolated peptide consisting of the sequence MKKDDQIAAAIALRGMA (SEQ ID NO:1) or an active variant thereof, wherein the peptide or active variant can bind specifically to an antibody induced by a causative agent of Lyme disea...
02/15/2011
7879367Metallic implant which is degradable in vivo
The invention relates to a medical implant made of a metallic material. After fulfilling its temporary support function, the implant is degraded by corrosion at a predetermined rate. Negative long-term effects are thus avoided. ...
02/01/2011
7875603Specific inhibitors for vascular endothelial growth factor receptors
The present application describes isoindoles and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful inhibitors of VEGFR. ...
01/25/2011
7829066Assay for anti-metastatic agents
This invention relates, e.g., to a method for identifying an agent that inhibits a metastatic cell (e.g. that inhibits cancer metastasis), comprising measuring the amount of seeding of a tumor by a detectably labeled, metastatic cell, in a subject, in the presence a...
11/09/2010
7772152Composite polymer-coated sorbent with a bidisperse pore size distribution for the simultaneous separation and desalting of biopolymers
A composite polymer-coated sorbent with a bidisperse or oligodisperse distribution of pore sizes and having an at least partial coating on its surface, which coating comprises essentially polyanilines or derivatives of polyanilines and use thereof for the simultaneo...
08/10/2010
7766811Methods and devices for improving cardiac output
Methods and devices are provided for improving cardiac output. The methods involve establishing a fluid communication pathway between the left ventricle and another natural or prosthetic structure. In one method, a conduit is implanted between the left ventricle and...
08/03/2010
7741357Heterocyclic and carbonate derivatives of NDGA and their use as new anti-HIV and anti-cancer agents
Reaction of nordihydroguaiaretic acid with various alkyl chlorides, 1-piperidinecarbonyl chloride, methyl chloroformate, or 1,1′-carbonyldiimidazole under alkaline conditions produced the corresponding phenol ethers, carbamates and carbonates, respectively, in 67-...
06/22/2010
7741287Peptides for the treatment of herpes virus infections
The present invention relates to the use of a peptide having the amino acid sequence NH2-VCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH-COOH (SEQ ID NO:1) as well as variants, derivatives and fragments of the peptide for the treatment of viral diseases. ...
06/22/2010
7700732Prekallikrein depleted plasma derived albumin fraction
An albumin containing fraction having a reduced prekallikrein activator (PKA) content and a method of manufacturing same comprising the steps of: (a) reconstitution of paste V (Cohn fractionation), (b) performing a concentration step of the...
04/20/2010
7671250Method of acquiring immunological tolerance
The aim of the present invention is to provide a method of acquiring immunological tolerance to a foreign DNA or its expression product whereby the foreign DNA such as a vector carrying a foreign gene incorporated thereinto or its expression product can be recognize...
03/02/2010
7648966Mannose-6-phosphonate compounds for the treatment of inflammatory diseases
Novel phosphotetrahydropyran compounds that mimic mannose-6-phosphate but that are more resistant to phosphatases and mannosidases, and pharmaceutical compositions thereof, are disclosed. These compounds and compositions inhibit T lymphocyte migration from blood to ...
01/19/2010
7638271Use of antibody from lymphocyte secretions to diagnose active infection
A method and kit for the detection of an infectious disease, particularly tuberculosis, wherein lymphocytes of a subject are incubated with a disease-specific antigen, and the level of antibody production is measured, the production of antibodies above a baseline le...
12/29/2009
7553938Method of providing a purified, virus safe antibody preparation
A method of preparing a purified, virus inactivated and virus safe antibody preparation from a starting solution comprising antibodies and contaminants, the method comprising the steps of: (a) adjusting the pH of the starting solution to about 4.6 to about 4.95 in p...
06/30/2009
7479536Chiral, charged peptide nucleic acid oligomers from cyclic monomers
A novel class of peptide nucleic acid compounds, which are positively charged, chiral analogs based on cyclic monomeric units, bind to complementary ssDNA, dsDNA and RNA strands with more affinity than the corresponding achiral, linear peptide nucleic acids, without...
01/20/2009
7432077High-affinity choline transporter
The present invention provides a protein having high-affinity choline transporter activity which is important physiologically, a gene encoding the protein, and a method of screening a material promoting the high-affinity choline transporter activity with the use of ...
10/07/2008
7407766Screening method for agonists or antagonists of semaphorin 6C by determining the effect of a test compound on the interaction between semaphorin 6C and plexin-A1
The present invention provides screening methods for agonists or antagonists of Sema6C using Plexin-A1, and tools for the screening and the like. It evaluates a case of making a recombinant protein having an extracellular domain of Semaphorin 6C contact a protein ha...
08/05/2008
7407984Tetraoxaspriro anti-malarials
The present invention is to provide an antimalarial agent having excellent antimalarial activity with little side effects, in particular, having remarkable antimalarial activity against drug-resistant malaria parasites, and being capable of increasing solubility not...
08/05/2008
RE40246Method for the suppression of viral growth
A method for suppressing undesired viral growth in a host which comprises administering to the host an effective amount of a compound of the formula: wherein R1, R2, R3 and R4 are indep...
04/15/2008
7341855Plant mangrove-associated fungus and a simple and efficient method of obtaining high yield of pure mannitol from the same
The present invention relates to a plant mangrove-associated fungus Curvularia lunata, and a simple and efficient method of obtaining high yield of pure mannitol from a plant mangrove-associated fungus Curvularia lunata, said method comprising steps of...
03/11/2008
7329795Model animals non-responsive to mycobacterial-origin lipoprotein/lipopeptide
The present invention is to provide TLR1 knockout mice specifically recognizing mycobacterial lipoproteins/lipopeptides, being useful to clarify the role of TLR1 in vivo, or a method for screening substances promoting or suppressing the response to mycobacterial lip...
02/12/2008
7316903Detection of nucleic acid sequence variations using phase Mu transposase
The present invention relates, e.g., to a method of detecting a mismatch in a double stranded nucleic acid target, comprising (a) contacting the target with (i) a Mu-end nucleic acid, and (ii) a phage Mu transposase, under conditions effective for the Mu-end nucleic...
01/08/2008
7317038Nerve regeneration promoters containing semaphorin inhibitor as the active ingredient
To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regene...
01/08/2008
7294710High-affinity choline transporter
The present invention provides a protein having high-affinity choline transporter activity which is important physiologically, a gene encoding the protein, and a method of screening a material promoting the high-affinity choline transporter activity with the use of ...
11/13/2007
7285282Mucin peptide with immunoenhancing properties
An isolated peptide or polypeptide containing the sequence VSIGLSFPMLP (SEQ ID NO:1), found in the secreted form of human MUC1, that enhances an immune response when administered to a mammal, compositions containing the peptide, host cells producing the peptide and ...
10/23/2007
7282620Type III allergic inflammation model animal
The present invention provides an experimental model animal which does not develop anaphylaxis, a type I allergy, can specifically induce Arthus reaction, a type III allergy, is not affected by type I allergy and evaluates type III allergy inflammation individually,...
10/16/2007
7276333Viral infection inhibitor targeting integrase N-terminal domain
The object of the present invention is to provide a screening method of a new integrase inhibitor being able to inhibit an HIV infection before the reverse transcription step and having a pharmaceutical site of action totally different from those of traditional inte...
10/02/2007
7276234Method of acquiring immunological tolerance
The aim of the present invention is to provide a method of acquiring immunological tolerance to a foreign DNA or its expression product whereby the foreign DNA such as a vector carrying a foreign gene incorporated thereinto or its expression product can be recognize...
10/02/2007
7271311Mammalian model for diabetes
An object of the present invention is to provide a model mammal for diabetes onset, being useful for elucidating the onset mechanism of diabetes caused by a blockage of signal transduction from insulin, and for the development of a remedy for said diabetes, and to p...
09/18/2007
7262162Ubiquitin and ubiquitin related molecules for treatment and prevention of harmful activation of the immune system
Compositions and methods for suppressing the immune system of a mammal using ubiquitin and derivatives and analogs thereof. ...
08/28/2007
7244761Nerve regeneration promoters containing semaphorin inhibitor as the active ingredient
To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic disease and a neurodegenerative disease containing said nerve regene...
07/17/2007
7229773Screening method for apoptosis-suppressing or-promoting substance
To provide a screening method for an apoptosis-suppressing substance or an apoptosis-promoting substance, the application of which substances to pharmaceuticals or diagnostic drugs are expected, also to provide an apoptosis-suppressing substance or an apoptosis-prom...
06/12/2007
7220588Method of altering levels of plasmids
The present invention relates to a method of obtaining altered plasmid contents in bacteria, bearing mutation in at least one of the chromosomal genes, nusG, rho, and dnaC, and the bacterial strains thereof, having the mutated chromosomal genes, individually or in v...
05/22/2007
7208609Method for producing thioctic acid
The invention relates to a method for producing pure racemic, R- or S-thioctic acid or mixtures thereof by reacting 6,8-disubstituted octanoic acid or their salts or esters with sulfides, sulfur or sulfites. ...
04/24/2007
7178316Ultrasonic sealing apparatus
An ultrasonic sealing apparatus is provided for transversely ultrasonically sealing a packing material comprised of a laminated body including at least a thermoplastic resin layer having a tubular form and containing a fluid. The apparatus includes a horn having an ...
02/20/2007
7176028Method of altering levels of plasmids
The present invention relates to a method of obtaining altered plasmid contents in bacteria, bearing mutation in at least one of the chromosomal genes, nusG, rho, and dnaC, and the bacterial strains thereof, having the mutated chromosomal genes, individually or in v...
02/13/2007
7166761Method of screening PTPζ activity promoter or inhibitor
An object of the present invention is to provide a remedy for dysfunction of central monoamine pathway, a method for screening a PTPζ inhibitor or activator, and a non-human model animal being hyposensitive to a stimulant drug, After administering a subject materia...
01/23/2007
7166476Highly reproducible agglutination immunoassay method and reagents
The present invention provides an agglutination immunoassay, wherein the agglutination of insoluble carrier particles such as latex are stabilized and uniformized to give good reproducibility, and a reagent therefor. In the agglutination immunoassay which comprises ...
01/23/2007
7157253Method for the production of (r)- and (S)-8-chloro-6-hydroxyoctanic acid alkyl esters by enzymatic reduction
The invention relates to a method for the production of (R)- or (S)-8-chloro-6-hydroxyoctanoic acid alkyl esters of the general formula (R)-II or (S)-II in which R has the meaning C1-4-alkyl, from 8-ch...
01/02/2007
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