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| Number | Title | Issue Date |
| 6920405 | Systems, methods and computer program products for constructing sampling plans for items that are manufactured A desired Acceptable Quality Limit (AQL), a desired Key Defect Rate (KDR), a desired power of a sampling plan for items that are manufactured and a desired false alarm rate for the sampling plan are input into a computer. The computer calculates a required sample si... | 07/19/2005 |
| 6433160 | Method for purification and manipulation of nucleic acids using paramagnetic particles The present invention relates to a composition which is useful for the reversible binding of a nucleic acid molecule. The composition, which may be packaged in a kit, includes a paramagnetic particle in an acidic solution.... | 08/13/2002 |
| 6399309 | Amplification and detection of mycoplasma pneumoniae targeting the ORF9 region of the hmw gene cluster Amplification primers and methods for specific amplification and detection of a hmw gene cluster target are disclosed. The primer-target binding sequences are useful for amplification and detection of Mycoplasma pneumoniae target in a variety of amplifica... | 06/04/2002 |
| 6379892 | Methods, kits and compositions of matter useful for determining Chlamydia pneumoniae Amplification primers and methods for specific amplification and detection of Chlamydia pneumoniae are disclosed. The primer-target binding sequences are useful for amplification and detection of Chlamydia pneumonia target in a variety of amplification an... | 04/30/2002 |
| 6350619 | Control particles for cell counting and instrument linearity This invention describes methods and kits for determining instrument linearity of a flow cytometer and is particularly useful as a control particle for use in conjunction with absolute cell counting methods. The particle used in the practice of this inven... | 02/26/2002 |
| 6316200 | Probes and methods for detection of nucleic acids The invention employs an unlabeled signal primer comprising a 5' adapter sequence for detection of nucleic acid target sequences. The detection system further comprises a reporter probe, the 3' end of which hybridizes to the complement of the 5' adapter s... | 11/13/2001 |
| 6287791 | Multidimensional cell differential analysis This invention relates to an improved method for the multi-parameter analysis of cells from peripheral blood or bone marrow. The method uses a nucleic acid dye, at least two fluorescently labelled monoclonal antibodies and at least two light scatter param... | 09/11/2001 |
| 6277582 | Amplification and detection of mycoplasma pneumoniae targeting the P1 gene Amplification primers and methods for specific amplification and detection of a P1 target are disclosed. The primer-target binding sequences are useful for amplification and detection of Mycoplasma pneumoniae target in a variety of amplification and detec... | 08/21/2001 |
| 6265224 | Sample processing method using ion exchange resin The present invention relates to methods in which ion exchange resins are used to reduce the amount of substances which interfere with nucleic acid hybridization in samples. The methods also stabilize the samples. Kits containing the ion exchange resins r... | 07/24/2001 |
| 6261785 | Amplification and detection of Bordetella pertussis Amplification primers and methods for specific amplification and detection of a pertussis toxin promoter target are disclosed. The primer-target binding sequences are useful for amplification and detection of Bordetella pertussis target in a variety of am... | 07/17/2001 |
| 6261784 | Detection of nucleic acids by strand displacement Detector nucleic acids are employed for detection of nucleic acid target sequences by fluorescence quenching mechanisms. The detector nucleic acid comprises at least two oligonucleotides and is partially single-stranded and partially double-stranded. One ... | 07/17/2001 |
| 6251609 | Amplification and detection of Legionella pneumophila targeting the mip gene Amplification primers and methods for specific amplification and detection of a mip gene sequence are disclosed. The primer-target binding sequences are useful for amplification and detection of Legionella pneumophila target in a variety of amplification ... | 06/26/2001 |
| 6241980 | Sample processing method using ion exchange resin The present invention relates to methods in which ion exchange resins are used to reduce the amount of substances which interfere with nucleic acid hybridization in samples. The methods also stabilize the samples. Kits containing the ion exchange resins r... | 06/05/2001 |
| 6218125 | Assay for Chlamydia trachomatis by amplification and detection of Chlamydia trachomatis cryptic plasmid A region of the Chlamydia trachomatis cryptic plasmid has been identified which is useful for performing amplification assays to determine specifically whether C. trachomatis is present in the sample being tested. Oligonucleotides useful for performing th... | 04/17/2001 |
| 6216049 | Computerized method and apparatus for analyzing nucleic acid assay readings A computerized method and apparatus are disclosed for analyzing numerical data pertaining to a sample assay comprising at least one biological or chemical sample. The data include a set of data pertaining to each respective sample, with each set of data i... | 04/10/2001 |
| 6210881 | Method for reducing inhibitors of nucleic acid hybridization The present invention relates to a method for reducing the amount of substances inhibitory to nucleic acid hybridization in samples. The method is practiced prior to release of target nucleic acid from cells of interest and involves contacting the sample ... | 04/03/2001 |
| 6207818 | Amplification and detection of shigella spp. and enteroinvasive strains of Escherichia coli Amplification primers and methods for specific amplification and detection of a Shigella spp. and enteroinvasive stains of Escherichia coli (EIEC) target are disclosed. The primer-target binding sequences are useful for amplification and detection of Shig... | 03/27/2001 |
| 6197514 | Amplification and detection of Yersinia enterocolitica Amplification primers and methods for specific amplification and detection of a Yersinia enterocolitica target are disclosed. The primer-target binding sequences are useful for amplification and detection of Y. enterocolitica target in a variety of amplif... | 03/06/2001 |
| 5519644 | Continuously calibrating temperature controller A multiple-loop temperature controller using RTD sensors is continuously calibrated by performing a zero or full scale calibration during each operating cycle. An arrangement of four multiplexers is used to successively connect each RTD sensor to a pair o... | 05/21/1996 |
| 5514554 | Methods and compositions for cancer therapy and for prognosticating responses to cancer therapy A method for determining the efficacy of a therapeutic agent, in vitro, for a cancer expressing or overexpressing an oncogene product is described. The method is particularly useful for determining the efficacy of therapeutic agents that have a binding af... | 05/07/1996 |
| 5512440 | Process for lysing Mycobacteria The invention provides a rapid process for lysing Mycobacteria. In one embodiment is provided a process for lysing Mycobacteria which comprises exposing the bacteria to a lysis effective amount of heat. A particularly effective method for providing the ne... | 04/30/1996 |
| 5503816 | Silicate compounds for DNA purification The present invention relates to a silicon-containing material which exhibits sufficient hydrophilicity and sufficient electropositivity to bind DNA from a suspension containing DNA and permit elution of the DNA from the material. Generally, the hydrophil... | 04/02/1996 |
| 5438127 | DNA purification by solid phase extraction using a PCl3 modified glass fiber membrane The present invention relates to modified glass fiber membranes which exhibit sufficient hydrophilicity and sufficient electropositivity to bind DNA from a suspension containing DNA and permit elution of the DNA from the membrane. Generally, the hydrophil... | 08/01/1995 |
| 5438129 | DNA purification by solid phase extraction using partially fluorinated aluminum hydroxide adsorbant The present invention relates to fluorinated surfaces which exhibit sufficient hydrophilicity and sufficient electropositivity to bind DNA from a suspension containing DNA and permit elution of the DNA from the surface. Generally, the hydrophilic and elec... | 08/01/1995 |
| 5405951 | Solid phase extraction purification of DNA The invention provides a method for purifying DNA from any source in any form. The method comprises the use of water soluble organic solvents when purifying DNA. By using water soluble organic solvents such as ethanol, propanol, and isopropanol, DNA is pu... | 04/11/1995 |
| 5376527 | Process for lysing mycobacteria The invention provides a rapid process for lysing Mycobacteria. In one embodiment is provided a process for lysing Mycobacteria which comprises exposing the bacteria to a lysis effective amount of heat. The process of the invention is particularly advanta... | 12/27/1994 |
| 5367058 | Modified antibodies with increased affinity The present invention relates to modified antibodies and fragments which display an increased affinity for antigen as compared to the affinity of unmodified antibody for antigen. The most preferred modification is the addition of a thiol group on the surf... | 11/22/1994 |
