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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8177900 | Compositions for use in making models Gypsum-based molding materials are customized by hydrating the molding material to workable (malleable) consistency with a moistening solution containing 0.001 to 60% polytetrafluoroethylene. The addition of latex results in a more flowable material. ... | 05/15/2012 |
| 8096424 | Method for fabrication of elastomeric asymmetric membranes from hydrophobic polymers Using the methods of the invention, an elastomeric polymer is dissolved in a suitable solvent, cast in one of the membrane casting techniques using a phase inversion technique, and immersed in a coagulation bath comprised of suitable solvent/non-solvent pairs (e.g.,... | 01/17/2012 |
| 8062610 | Apparatus and methods for use in concentration of gas and particle-laden gas flows For analysis of small quatities of target analytes in an environment, the gas flow can be delivered to a suitably fast analyzer and their concentration determined in a time period whose duration is dependent on the analyte, its concentration and the phase separation... | 11/22/2011 |
| 7854651 | Highly bacteriocidal chlorine dioxide, formulation, preparation and use thereof When used as a biocide on newly butchered chickens, chlorine dioxide at concentrations of 12 to 50 ppm is effective at temperatures of 35° C. to 90° C. with 15 ppm being very effective at temperatures of 45° C. to 60° C. Chlorine dioxide in about 50° C. water d... | 12/21/2010 |
| 7622045 | Hydrophilic cross-linked polymeric membranes and sorbents Hydrophilic cross-linked polymeric membranes, when prepared according to the process of the present invention, are unique in character in as much as the steady state permeability of the membrane has been altered by blending and cross-linking polyalkyl amines and pol... | 11/24/2009 |
| 7485233 | Hydrophilic mixed matrix material having reversible water absorbing properties Polymer-ceramic mixed matrix compositions contain one or more organic polymers and a nano-sized dispersion of inorganic metal oxide particles which are dispersed throughout the composition. Materials have use in making membranes that act as transfer agents. ... | 02/03/2009 |
| 7312305 | Tumor cytotoxicity induced by modulators of the CXCR4 receptor The present invention provides a means of selectively killing epithelial cell carcinomas by administering a CXCR4-specific sequence of the Gp120 protein or Nef proteins or the proteins themselves (the modulators) such as that found in strains HIV-1, HIV-2, SIV, or F... | 12/25/2007 |
| 7148033 | Method for detection for total coliforms and An improved method for detection of total coliforms and E. coli comprising a broth containing an ingredient that will suppress growth of non-coliform gram negative bacteria, and at least one chromogen or fluorogen has been used effectively and is cost effecti... | 12/12/2006 |
| 6884790 | Verifiable absorption drug delivery form based on cyclodextrins Solid dosage forms are produced by absorbing solutions of drug:cyclodextrin inclusion complexes on absorbing matrices and then drying. The matrices may, but need not, disintegrate in water. The resulting forms are suitable for oral or sublingual administration, and ... | 04/26/2005 |
| 6858399 | Test for oxidative stress using cell suspensions This invention provides a method of measuring oxidative response of cells without recourse to preparation of cell culture. The process involves: 1) preparing suspensions of cells from a living host in isotonic solutions, ... | 02/22/2005 |
| 6743893 | Receptor-mediated uptake of peptides that bind the human transferrin receptor Peptides have been discovered which are capable of binding to and internalizing with the human transferrin receptor (hTfR). The sequences HAIYPRH (Seq. ID No. 1) and THRPPMWSPVWP (Seq. ID No. 2) are capable of binding to and internalizing with the human transferrin ... | 06/01/2004 |
| 6645532 | Compositions and method for relieving discomfort in the ears Generally, the method for preventing or relieving discomfort in the ears arising from congestion and/or obstruction of in the eustachian tubes comprising or changes in middle ear pressure relative to atmospheric pressure arising from environmental conditi... | 11/11/2003 |
| 6602860 | Crystalline mixtures of partial methyl ethers of beta-cyclodextrin and related compounds Certain mixtures of cyclodextrin derivatives, which were synthesized in mildly basic conditions, can be separated into mixtures that crystallize easily and mixtures of similar composition, which remain amorphous. Thus, it is possible to obtain the particu... | 08/05/2003 |
| 6583280 | Polyamine analogues having antiproliferative activity Novel compounds are chiral compounds which are conformationally restricted polyamine analogues for use in imaging and for therapeutic use in treatment of tumors. These analogues diminish the ability to aggregate DNA seen in the parent polyamines. The inve... | 06/24/2003 |
| 6576261 | Potentiation of inclusion complex formation of cyclodextrin derivatives A method is disclosed for the potentiation of formation of inclusion complexes of electroneutral and anionic compounds. Included are compositions containing complexes of two different cyclodextrin species. New complexes containing as guest molecules activ... | 06/10/2003 |
| 6371944 | Percutaneous needle with entry for insertion of a wire A needle is attached to a connector portion having a common passage with an an arm with a lumen that has a one-way valve which prevents flow of fluid from the needle through the lumen of the arm which acts as a conduit for insertion of a wire into the cha... | 04/16/2002 |
| 6306621 | Membrane filter agar medium for simultaneous detection of total coliforms and E. coli An improved method for detection of total coliforms and E. coli comprising a broth containing an ingredient that will encourage growth and repair of injured coliforms, buffers to maintain a pH in the range of 6.5-8, at least one agent that suppresses grow... | 10/23/2001 |
| 6251221 | Process for preparing cellulose from lignin-poor cellulose-containing feed stocks The method of the invention involves treating cellulosic vegetable matter (the "Feed Stocks") for the selective recovery of lignin (when present in the feed-stock), cellulose and hemi-celluloses by: (1) reducing the material to be processed to an appropri... | 06/26/2001 |
| 6247927 | Disposable articulator having tray support with opening which accepts a projection from a tray This invention provides a device for use in making dental models comprising a tray support a having an opening and a tray having an inferior surface with a projection from said inferior surface of said tray, wherein said projection of said tray fits into ... | 06/19/2001 |
| 6218130 | Test for oxidative stress using cell suspensions This invention provides a method of measuring oxidative response of cells without recourse to preparation of cell culture. The process involves: 1) preparing suspensions of cells from a living host in isotonic solutions, 2) preparing samples of test materials in is... | 04/17/2001 |
| 6153182 | Lymphotactin as an adjuvant Compositions of lymphotactin in cellular immune enhancing amounts may advantageously be administered at very low levels in conjunction with vaccines to provide improved immune response, Suggested dosage such as 1 to 10 ηg in small animals and from 10 μg... | 11/28/2000 |
| 6133200 | Herbicidal compositions containing DMSO The addition of DMSO to herbicidal compositions makes it possible to decrease the amount of active herbicidal agent required for desired activity without loss of effectiveness against target plants. In some instances, it may be advisable to use up to as 5... | 10/17/2000 |
| 6063590 | Membrane filter agar medium containing two enzyme substrates used for the simultaneous detection of total coliforms and E. coli. An improved method for detection of total coliforms and E. coli comprising placing the target sample in a broth containing an ingredient that will encourage growth and repair of injured coliforms, at least one agent that suppresses growth of gram positive... | 05/16/2000 |
| 6051159 | Soft ice This invention relates to a preferred composition for use in preparation of flexible cold packs which are useful for medicinal, research and other uses where cooling to low temperatures is required.... | 04/18/2000 |
| 6001821 | Dioxane-substituted cyclodextrin macromolecules and inclusion complexes The preparation of compositions containing cyclodextrin moieties which are modified by fusing 1,4 dioxane rights to glucopyranosyl residues is described. These compositions are suited as carrier for pharmaceuticals, agricultural chemicals and... | 12/14/1999 |
| 5935941 | Alkylations of cyclodextrins leading to derivatives which have a ridgidly extended cavity By controlling basicity of the reaction, is possible to alkylate preferentially the secondary hydroxyls of cyclodextrins. These hydroxyls surround the principal, wide, entry into the cyclodextrin cavity and, thus, their substitution by suitably chosen sub... | 08/10/1999 |
| 5859236 | Process for preparation of lignin and microcellulose The method of the invention involves treating cellulosic vegetable matter (the "Feed Stocks") for the selective recovery of lignin (when present in the feed-stock), cellulose and hemicelluloses by: (1) reducing the material to be processed to an appropria... | 01/12/1999 |
| 5824337 | Synthetic membranes forming micelles and micelle-like structures comprising lipo-glycoprotein membranes Micelles are produced having a membrane wherein the outer surface is hydrophilic and the interior of said micelle contains at least one lipophilic group. If a lipophilic material will not form strong micelles, it is possible, using methods of the inventio... | 10/20/1998 |
| 5792468 | Lime feeding repellent Application of lime at a rate of 500 to 1500 kg/ha to plots desired to be protected from damage by avian and mammalian feeders has been shown to be quite effective. The lime may be administered to the plots in any form. Use of either powder or slurry form... | 08/11/1998 |
| 5776921 | Compositions for regulation of immune responses Androsta-5,7-diene-3ଲ, 17ଲ-diol, its esters and ethers and related compounds wherein ring opening of the steroid ring system between carbons 9 and 10 has occurred are active as regulators of immune response and cell proliferation and different... | 07/07/1998 |
| 5559107 | Regulation of immune response Androsta-5,7-diene-3ଲ,17ଲ-diol, its esters and ethers and related compounds wherein ring opening of the steroid ring system between carbons 9 and 10 has occurred are active as regulators of immune response and cell proliferation and differenti... | 09/24/1996 |
| 5527122 | Protective cover for keyboards or control panels This invention is a protective cover for a keyboard or other control panel with attachment means, using different options as preferred for specific equipment. The cover can be separately obtained and secured to the housing or chassis of various equipment.... | 06/18/1996 |
| 5445650 | Temporomandibular joint prosthesis A total temporomandibular joint prosthesis for the replacement of the mandibular condyle. The prosthesis including an elongated plate having openings for attachments to the mandible. The plate having a shape such that the lateral and inferior edges of the... | 08/29/1995 |
| 5288262 | Crazy wheels toy A push wheel toy is disclosed where a handle is attached to pair of wheels on an axle. The axle is contorted so that the wheels are not necessarily parallel nor will the toy move in a straight line unless carefully controlled. The handle is loosely attach... | 02/22/1994 |
| 5256406 | Treatment of hair loss and dermatological problems It has been found that loss of hair and malfunction of the lubricating function of the skin can be treated with small mounts of testosterone or house dust antigen given in desensitizing doses. Treatment with minidoses of testosterone or house dust suspens... | 10/26/1993 |
| 5206008 | Enhancement of immune response The present invention provides an improved means for regulating the immune response, for ameliorating effects of stress, and for avoiding untoward effects of chemotherapy or exposure to irradiation by administration of androstenediol (AED) and androstenet... | 04/27/1993 |
| 5160340 | Autopsy apparatus Method and apparatus for skullcap and other bone cutting during autopsy. A power driven rotary cutter in the form of a circular blade saw is mounted on a carrier which moves around the skull of the cadaver and permits the cutter to move radially, toward a... | 11/03/1992 |
| 5119708 | Curved blades for reciprocating saws This invention relates to saw blades for use in reciprocating hand-manipulated saws. The blades of the invention have a straight, untoothed edge lying parallel to the longitudinal axis of the blade and a toothed edge wherein at least 30% of the toothed ed... | 06/09/1992 |
| 5084441 | Acetylated low density lipoproteins: a delivery system to phagocytic cells for stimulating immunologic response and host resistance Acetylated low density lipoproteins are combined with active and effective lipophilic peptide or other lipophilic immunomodulators, antigens or vaccines to carry the same to macrophage specific targeted receptor mediated endocytosis sites in a living syst... | 01/28/1992 |
| 5077284 | Use of dehydroepiandrosterone to improve immune response The steroid hormone dehydroepiandrosterone (DHEA), when administered by feeding or by subcutaneous injection, significantly improves the host response to viral infection. Experimental animal data shows that, with infection (100,000 plaque forming units/an... | 12/31/1991 |
