Heller Ehrman White and McAuliffe - US Patent Attorneys and Agents

Attorney: Heller Ehrman White and McAuliffe

Number of patents: 76
Last date: May 31, 2005

Number	Title	Issue Date
6737072	Matrix for tissue engineering formed of a hyaluronic acid ester and hydrolyzed collagen A porous composite matrix is formed from a hyaluronic acid derivative and hydrolyzed collagen, which are preferably in a weight ratio range of 30:70 to 99:1. A preferred hyaluronic acid derivative is an ester such as an ethyl or benzyl ester. The matrix is prepared ...	05/18/2004
6899066	Valve assembly A valve assembly for a motorcycle engine including a valve body and a plurality of reed valve constructions. The valve assembly is configured for receipt within an aperture of an engine wall extending between the crankcase and the cam chest of the engine. In particu...	05/31/2005
6833132	Method of stimulating epithelial cells using keratinocyte growth factor (KGF) and method of inhibiting KGF activity Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used sucessfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional f...	12/21/2004
6794359	Vertebrate intestinal protein which absorbs cholesterol, its inhibitors and mehtod of identifying the same The invention relates to a vertebrate intestinal protein which absorbs cholesterol. It was possible to identify the protein by means of high-affinity crosslinking compounds. The invention further relates to this use of the protein for carrying out a method for ident...	09/21/2004
6759424	Imidazolidine derivatives, their preparation, their use, and pharmaceutical preparations comprising them The present invention relates to novel imidazolidine derivatives of the formula I, in which B, E, W, Z, R, R0, R2, R3, e and h have the meanings indicated in the application. The compound...	07/06/2004
6753136	Methods for displaying (poly) peptides/proteins on bacteriophage particles via disulfide bonds The present invention relates to methods for displaying (poly)peptides/proteins on the surface of bacteriophage particles by attaching the (poly)peptide/proteins via disulfide bonds. ...	06/22/2004
6750353	Preparation of pharmaceutically acceptable atorvastatin salts in non-crystalline form Non-crystalline, in particular amorphous, pharmaceutically acceptable atorvastatin salts, especially the calcium salt, are prepared from atorvastatin lactone or from a compound of formula (I) where A denotes a common pro...	06/15/2004
6749886	Confectionery product made of protein and carbohydrate materials present in a relative weight ratio higher than 1 The invention provides a confectionery bar having a proteinaceous material and a carbohydrate material in a relative weight ratio higher than 1 (from 1:0 to about 1:0.999). The bar produced is very palatable and chewy and has good organoleptic properties. It may be ...	06/15/2004
6725563	Drying method, drying device, and drying machine A drying method, a drying device, and a drying machine, capable of remarkably reducing a drying time by assigning the standby time for an article to be dried to a preliminary drying time in drying, wherein hot air is supplied to the drying machine so as to dry the a...	04/27/2004
6709842	DNA encoding a growth factor specific for epithelial cells Disccoveries are disclosed that show particular aspects of recombinant DNA technology can be used sucessfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of other polypeptides. These proteins can be produced in various functional ...	03/23/2004
6708137	System and method for providing composite variance analysis for network operation A system and method collects measurements of network performance metrics and automatically calculates and provides composite variance analysis of such metrics. The system and method may use history of performance data statistics to alert a user about performance of ...	03/16/2004
6706484	Protein/(poly)peptide libraries The present invention relates to synthetic DNA sequences which encode one or more collections of homologous proteins/(poly)peptides, and methods for generating and applying libraries of these DNA sequences. In particular, the invention relates to the preparation of ...	03/16/2004
6706278	Pigment- containing materials to be added to feeds This invention provides a pigment-containing substance for feed additives consisting of a microorganism culture precipitate which contains a high concentration of carotenoid compounds. This pigment-containing substance for feed additives is resistant to oxygen, ligh...	03/16/2004
6703038	Injectable bone substitute material containing non-ceramic hydroxyapatite cement A bone substitute material is prepared which comprises a soft matrix, living cells and a setting matrix comprising non-ceramic hydroxyapatite cement. The bone substitute material can be injected minimally invasively into a bone defect with a suitable inje...	03/09/2004
6703202	Evaluating and predicting clinical outcomes by gene expression analysis Methods of determining clinical outcomes in patients suffering from a pathological condition or syndrome are provided. Levels of intracellular gene expression re measured from a clinical sample provided by the patient, and the levels are compared to refer...	03/09/2004
6695889	Pre-dyeing treatment process and dyeing process for textile products containing highly crosslinked polyacrylic fibers, pretreated and undyed textile product, and dyed textile product In textile products (e.g. yarns, woven fabrics, knit fabrics) comprising highly crosslinked polyacrylic fibers (made of acrylic fibers by partially hydrolyzing a nitrile group to generate an amido group and a carboxylic acid group), fibers blended with th...	02/24/2004
6696248	Protein/(poly)peptide libraries The present invention relates to synthetic DNA sequences which encode one or more collections of homologous proteins/(poly)peptides, and methods for generating and applying libraries of these DNA sequences. In particular, the invention relates to the prep...	02/24/2004
6686397	Polysubstituted indan-1-ol systems for the prophylaxis or treatment of obesity Polysubstituted indan-1-ol compounds of formula I, its physiologically acceptable salts and physiologically functional derivatives are disclosed: ##STR1## Compositions comprising the same, methods of preparation and methods for the prophylaxis or treatmen...	02/03/2004
6680333	Imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them The present invention relates to novel imidazolidine derivatives of formula I, ##STR1## wherein A, E, Z, R1, R2, R3, R4 and R5 have the meanings indicated in the claims. The compounds of formula I are...	01/20/2004
6673609	Recombinant human erythropoietin with advantageous glycosylation profile A method for the production of a polypeptide, the method comprising culturing, under conditions which allow for the expression of DNA encoding SEQ ID NO:2 in an eukaryotic host cell, wherein the DNA is in vector pPHOEBE-40-7, and optionally isolating the ...	01/06/2004
6670147	Nucleic acid construct for expressing active substances which can be activated by proteases, and preparation and use The invention relates to a nucleic acid construct for expressing an active substance which is activated by an enzyme which is released from mammalian cells, which construct comprises the following components: a) at least one promoter element, b) at least ...	12/30/2003
6670401	Polysubstituted indan-1-ol compounds, and methods for their preparation and use Polysubstituted indan-1-ol compounds, methods for their preparation; and methods for their use are disclosed herein. In particular, the invention relates to polysubstituted indan-1-ol compounds of the formula I ##STR1## and their physiologically acceptabl...	12/30/2003
6667334	Imidazolidine derivatives, the production thereof, their use and pharmaceutical preparations containing the same The present invention relates to imidazolidine derivatives of the formula I, ##STR1## in which B, E, W, Y, R, R2, R3, R30, e and h have the meanings indicated in the claims. The compounds of the formula I are valuable...	12/23/2003
6667150	Method and phage for the identification of nucleic acid sequences encoding members of a multimeric (poly) peptide complex The present invention relates to methods for the identification of nucleic acid sequences encoding members of a multimeric (poly)peptide complex by screening for polyphage particles. Furthermore, the invention relates to products and uses thereof for the ...	12/23/2003
6667345	Derivatives of C2-substituted indan-1-ol systems for the prophylaxis or treatment of obesity Derivatives of C2-substituted indan-1-ol compounds of the formula I: ##STR1## its physiologically acceptable salts, and its physiologically functional derivatives for the prophylaxis or treatment of obesity are disclosed herein. Compositions comprising th...	12/23/2003
6653068	Generation of specific binding partners binding to (poly)peptides encoded by genomic DNA fragments or ESTs The present invention relates to the generation of specific binding partners binding to (poly)peptides encoded by genomic DNA fragments or ESTs. The (poly)peptides are expressed as part of fusion proteins which are forming inclusion bodies on expression i...	11/25/2003
6629960	Needle hub for medical instrument A medical instrument includes a needle nozzle that accepts a needle cam. A needle hub assembly includes a needle hub and a needle cannula, and when registration ribs of the needle hub are fitted between respective registration ribs of the needle cam, the ...	10/07/2003
6630356	Photoluminescent semiconductor materials Semiconductor materials having a porous texture are modified with a recognition element and produce a photoluminescent response on exposure to electromagnetic radiation. The recognition elements, which can be selected from biomolecular, organic and inorga...	10/07/2003
6630317	Methods for obtaining, identifying and applying nucleic acid sequences and (poly)peptides which increase the expression yields of periplasmic proteins in functional form The present invention relates to a method for obtaining nucleic acid sequences encoding (poly)peptides which increase the expression yields of periplasmic proteins in functional form upon co-expression of said (poly)peptides and said periplasmic proteins....	10/07/2003
6620444	Two-compartment container for and method of admixing a flavour to a beverage The present invention is directed to a two-compartment container for receiving a flavour for the mixture thereof with a main beverage liquid in a beverage container immediately after opening the beverage container, one compartment of which comprises a sma...	09/16/2003
6617131	Nucleic acid molecule encoding the potassium channel protein, KCNQ5 KCNQ5, DNA encoding KCNQ5 or a polypeptide having KCNQ5 activity, related vectors, host cells and methods and a screening assay for identification of compounds which modify activity of a potassium channel KCNQ5 are described....	09/09/2003
6610473	Peptides for inhibiting HPV E6-proteins The present invention relates to peptides suited for inhibiting HPV-E6 proteins, DNAs encoding them and the use of both, particularly for eliminating HPV tumor cells....	08/26/2003
6602699	Promotor for functional characterization of G-protein coupled receptors in the yeast saccharomyces cerevisiae The present invention relates to a promoter, to DNA fragments containing said promoter and to the use thereof, in particular in methods for identifying substances exhibiting an activating or inhibiting action on G protein-coupled receptors....	08/05/2003
6596120	Refractory lined ducts and coating for use therewith The present invention is directed to ceramic fiber insulation and related products and methods. A coating that is capable of being brushed and/or sprayed lightly as a liquid onto vacuum-formed ceramic fiber insulation for use at high temperatures is also ...	07/22/2003
6592428	Foundation garment for the relief of menstrual discomfort In order to reduce discomfort induced by menstruation, a panty girdle or the like type of foundation garment is provided with an extensible bladder or a non-extensible element which is arranged to apply pressure to one or both of the sacral or parasacral ...	07/15/2003
6589157	Drive mechanism for medical instrument A medical instrument includes a drive train assembly that causes precise index movement of the medical instrument, based on an operator-selected indexing amount resulting from actuation of a pitch adjustment knob on the medical instrument. The drive train...	07/08/2003
6589741	Polysome display in the absence of functional ssrA-RNA The present invention relates to methods for identifying nucleic acid molecules encoding (poly)peptides that interact with target molecules. The method of the present invention is particularly characterized by an in vitro translation step under conditions...	07/08/2003
6575890	Medical instrument A medical instrument provides for precise indexing in order to implant seeds into seed implant locations within a patient. The medical instrument is affixed to a targeting fixture, and upon operator actuation of a trigger, is automatically indexed from on...	06/10/2003
6576758	Nucleic acid constructs containing hybrid promoters Nucleic acid constructs containing hybrid promoters for use in gene therapy and genetic manipulation. The invention relates to a nucleic acid construct for the precise, regulated expression of genes in host cells, which construct exhibits at least one mut...	06/10/2003

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Attorney: Heller Ehrman White and McAuliffe