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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 6361773 | Antibodies produced against cytokine suppressive anti-inflammatory drug binding proteins This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene ... | 03/26/2002 |
| 6309854 | Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72 Polypeptides of HFGAN72 receptor ligands and polynucleotides encoding the polypeptides are provided. Methods of using these polypeptides to diagnose diseases relating to the under- or over-expression of HFGAN72 receptor ligands are also provided. In addit... | 10/30/2001 |
| 6232097 | Arginyl tRNA synthetase polynucleotides The invention provides argS polypeptides and DNA (RNA) encoding argS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing argS polypeptides to screen for antibacterial compounds.... | 05/15/2001 |
| 6218136 | Methods of the identification of pharmaceutically active compounds CSBP/p38 is a MAP kinase that is activated in response to stress, endotoxin, interleukin 1 and tumor necrosis factor. Using a catalytically inactive mutant (D168A) of human CSBP2 as the bait in a yeast two-hybrid screen, a kinase has been cloned which sha... | 04/17/2001 |
| 6214866 | Composition comprising mupirocin and chlorhexidine Pharmaceutical compositions comprising mupirocin and chlorhexidine are of use in treating topical bacterial infections, in particular infected burn injuries.... | 04/10/2001 |
| 6166193 | Polynucleotides encoding MY1 receptor MY1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing MY1 polypeptides and polynucleotides in the design of protocols for the treatment of infecti... | 12/26/2000 |
| 6156792 | Calcium mupirocin non-aqueous nasal spray for otitis media or for recurrent acute bacterial sinusitis Mupirocin or a salt or ester thereof may be used to treat recurrent sinusitis and recurrent otitis, in particular with novel spray or cream formulations adapted for administration to the nasopharynx... | 12/05/2000 |
| 6153441 | Methods of screening for agonists and antagonists for human CCR7 receptor and CKଲ-9 ligand and interaction thereof Disclosed are methods for discovering agonists and antagonists of the interaction between a secreted human protein, chemokine CKଲ-9, and its cellular receptor, human CCR7, which may have utility in the treatment of several human diseases, including,... | 11/28/2000 |
| 6150150 | Human brain phosphodiesterase Isolated cDNA clones from human brain (frontal cortex) cDNA libraries that encode a unique subtype of the low Km, cAMP-specific phosphodiesterases (PDE IVs) are disclosed. Analysis of the distribution of hPDE IVB mRNA expression in v... | 11/21/2000 |
| 6114127 | Methods of screening for agonists and antagonists of the HDPXU17 receptor HDPXU17 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods of screening for agonists and antagonists of the interaction between the HDPXU17 receptor and its liga... | 09/05/2000 |
