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"I hate what they've done to my child...I would never let my own children watch it. "
Vladimir Zworykin, television pioneer ; Talking about an invention in which he played a critical role.
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| Number | Title | Issue Date |
| 8138205 | Heteroarylalkoxy-substituted quinolone inhibitors of PDE4 The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators. | 03/20/2012 |
| 8080566 | Carbazole inhibitors of histamine receptors for the treatment of disease The present invention relates to carbazole compounds, pharmaceutical compositions comprising them, and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular... | 12/20/2011 |
| 8080563 | Bicyclic heteroaryl inhibitors of PDE4 The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PD E4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators. | 12/20/2011 |
| 8063227 | Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron a... | 11/22/2011 |
| 7960570 | Small molecule inhibitors of rotamase enzyme activity This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamas... | 06/14/2011 |
| 7915253 | Sulfonyl-substituted bicyclic compounds as modulators of PPAR Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed. ... | 03/29/2011 |
| 7863276 | Salts of modulators of PPAR and methods of treating metabolic disorders Salt forms of potent modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed. ... | 01/04/2011 |
| 7834004 | Sulfonyl-substituted bicyclic compounds as modulators of PPAR Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed. ... | 11/16/2010 |
| 7825256 | Inducible nitric oxide synthase dimerization inhibitors The present invention relates to compounds and methods useful as inhibitors of nitric oxide synthase. Certain compounds of the subject invention have the following structural formula: wherein T, X, and Y are independently s... | 11/02/2010 |
| 7795216 | Methods for promoting composite tissue regeneration and uses thereof The present invention provides a use and method for GM284 to promote the regeneration of a bodily structure comprised of a composite tissue in a subject. Additionally, the present invention provides a use and method for GM284 to promote composite tissue regeneration... | 09/14/2010 |
| 7745646 | Bicyclic heteroaryl inhibitors of PDE4 The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators. | 06/29/2010 |
| 7652060 | Small molecule rotamase enzyme inhibitors This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamas... | 01/26/2010 |
| 7517884 | Sulfonyl-substituted bicyclic compounds as modulators of PPAR Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed. ... | 04/14/2009 |
| 7494999 | Sulfonyl-substituted bicyclic compounds as modulators of PPAR Compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed. ... | 02/24/2009 |
| 7470722 | Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease Disclosed herein are carbonyl compounds of Formula I as described herein. Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central n... | 12/30/2008 |
| 7459473 | N-linked sulfonamides of N-heterocyclic carboxylic acids or carboxylic acid isosteres This invention relates to novel N-linked sulfonamides of N-heterocyclic carboxylic acid and carboxylic acid isosteres, their preparation, and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating... | 12/02/2008 |
| 7271195 | Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease Disclosed herein are carbonyl compounds of Formula I, II, or III, and others as described herein. Also disclosed are methods of treating disease, such as cancer, neurological disorders, including polyglutamine-repe... | 09/18/2007 |
