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Patent No. 5979328

Vehicular Impact Signaling Device

An apparatus for the deployment of a visible plume to alert other motorists that a proximate motor vehicle has been involved in a collision.

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Attorney: Harris; Charles H., Moran; John Francis


Number of patents: 19
Last date: November 13, 2001

NumberTitleIssue Date
6316006Asporogenic B anthracis expression system
This invention relates to a bacterial expression system for production of protective antigen (PA) against bacillus anthracis. Recombinant asporogenic B. anthracits that are derived from ƊSterne-1(pPA102) and show inability to bind the dye when grown on C...
11/13/2001
6310046Sequestrin of Plasmodium falciparum
In this application is described the expression cloning and functional characterization of the CD36-binding domain of Sequestrin. Sequestrin is a surface protein of 215-250 kD size which does not vary in size between parasite strains. The Sequestrin gene ...
10/30/2001
6124108Protein biomarker for mustard chemical injury
This invention relates to the discovery that toxicity to mustard may be euated by diagnostic test means disclosed herein. Upon electrophoretic separation (sodium dodocyl sulfate polyacryl-amide gel electrophoresis (SDS-PAGE)) of buffered extract of human...
09/26/2000
6117640Recombinant vaccine made in E. coli against dengue virus
A recombinant protein encompassing a C-terminal protion from the structural envelope glycoprotein and an N-terminal portion from non-structural protein one of dengue type 2 virus was expressed in Escherichia coli as a fusion protein with Staphylococcal pr...
09/12/2000
6074865Recombinant dengue virus DNA fragment
A recombinant protein encompassing the complete envelope glycoprotein and a portion of the carboxy-terminus of the membrane/premembrane protein of dengue 2 virus was expressed in baculovirus as a protein particle. The recombinant protein particle was puri...
06/13/2000
6066323Use of antibodies to sialidase as anti-infectious agents and anti-inflammatory agents
Sialic acids have the ability to prevent hyposialylation of cells as comptive inhibitors of endogenous sialidase. It is now also possible to develop antibodies to mammalian sialidase that significantly reduce influx of neutrophils into inflammatory sites...
05/23/2000
6046806Flow-through cell culture chamber
Provided is a flow-through cell culture chamber having an internal chamber or containing cultured cells defined in part by transparent cover slips. Fastening and retainer structures are utilized to urge the cover slips towards one another and seal the inte...
04/04/2000
6008329Method for purifying cholera toxin
The invention relates to a method of purifying cholera toxin using a matrix with at least one ion chosen from among matrix with Ni+2, Co+2, Cd2 or Zn+2 immobilized thereon. It is possible thereby to selectively ...
12/28/1999
6007838Process for making liposome preparation
A process for making a liposome preparation comprised of liposomes that contain an encapsulated material is disclosed. The process comprises (A) providing a plurality of portions of a lipid or liposome formulation; (B) hydrating each of the plurality of p...
12/28/1999
6001625Site-directed mutagenesis of esterases
A method of modifying esterases by substitution with histadine of at least one amino acid within 6 Å of an active site serine provides esterases useful for detoxifying organophasphates....
12/14/1999
5983557Lethal mosquito breeding container
Provided is a breeding container which is adapted to be lethal to container breeding mosquitoes which contains: a walled structure defining an internal volume, the walled structure being constructed and arranged to contain an aqueous liquid within at least a ...
11/16/1999
5965572Methods for treating antibiotic-resistant infections
This invention relates to the treatment of antibiotic-resistant infections, including particularly infections caused by bacteria, Mycobacteria and gi. A preferred group of compositions of the invention contain as active agents compounds containing pyrid...
10/12/1999
5965699Assay for the proteolytic activity of serotype a from clostridium botulinum
A label-based assay is described, through modifications of substrate strure and derivatization of serum albumin, which can be used to determine type A proteolytic activity without separation of products....
10/12/1999
5958686Simple PCR technique for detecting and differentiating bacterial pathogens
A simple polymerase chain reaction procedure is described for the detection and differentiation of Shigella from other pathogenic Escherichia coli isolates, such as EIEC and EPEC. Serotype specific primers derived from the rfc genes of different Shigella ...
09/28/1999
5939075Mutants of Brucella melitensis
The vaccines are prepared by isolating the Brucella genes complementing mutations in the purEK genes of Escherichia coli, physically mapping, determining the DNA sequence, constructing a defined deletion mutation by polynucleotide chain reaction (PCR), in...
08/17/1999
5919129Fiber optic periodontal endoscope
A fiber optic periodontal endoscope includes a lens and light housing assly attached to a handle end tip containing fiber optic bundles transmitting light from the source to illuminate the probe tip. The returning image traveling back through the handle ...
07/06/1999
5914114Method of raising antibodies against E. coli of the family CS4-CFA/I
A consensus poptide of 36 amino acids has been designed which acts as an immunogen raising antibodies against the proteins of all members of the E. coli family CS4-CFA/1. While the N-terminus of members of this family of organisms shows a high degree of i...
06/22/1999
5888519Encapsulated high-concentration lipid a compositions as immunogenic agents to produce human antibodies to prevent or treat gram-negative bacterial infections
This invention is directed to the production of antibodies against lipid A by using encapsulating slow-releasing delivery materials or devices containing concentrations of lipid A that are greater than could be given safely to humans in the absence of sai...
03/30/1999
5824538Shigella vector for delivering DNA to a mammalian cell
We describe a bacterial delivery system for the delivery of DNA and antigens into cells. We constructed an attenuated bacterial vector which enters mammalian cells and ruptures delivering functional plasmid DNA, such as a mammalian expression plasmid, and...
10/20/1998
 
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