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Attorney: Harper; David S.


Number of patents: 18
Last date: May 19, 2009

NumberTitleIssue Date
7534875Compositions for glioma classification
The present invention provides novel compositions and their use in classifying gliomas. In a preferred embodiment, the methods are used to discriminate between oligodendroglioma and glioblastoma. ...
05/19/2009
7381699Reagents and methods for smooth muscle therapies
The present invention provides novel polypeptides comprising heat shock protein 20(HSP20)-derived polypeptides to treat or inhibit smooth muscle vasospasm, as well to treat and inhibit smooth muscle cell proliferation and migration. ...
06/03/2008
6916783Methods for accelerating bone and cartilage growth and repair
The present invention provides improved methods, kits, and compositions for enhancing bone, cartilage and cartilage repair, bone and prosthesis implantation, and attachment and fixation of cartilage and cartilage to bone or other tissues, and chondrocyte proliferati...
07/12/2005
6905881Microbead-based test plates and test methods for fluorescence imaging systems
The present invention provides a test plate and methods for adjusting fluorescence imaging systems involving using a plate with fluorescent microbeads bound to a surface. ...
06/14/2005
6902883System for cell-based screening
The invention relates to an optical system for determining the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for specific biological activity. The invention involve...
06/07/2005
6881547Methods and reagents for treating autoimmune disorders
The present invention provides methods and reagents for identifying compounds to treat autoimmune diseases. ...
04/19/2005
6703363Recombinant laminin 5
The present invention provides recombinant laminin 5, methods for making recombinant laminin 5, cells that express recombinant laminin 5, and methods for using the recombinant laminin 5 to accelerate wound healing, and to promote cell attachment and migra...
03/09/2004
6671624Machine readable storage media for detecting distribution of macromolecules between nucleus and cytoplasm in cells
The present invention provides systems, methods, and screens for an optical system analysis of cells to rapidly determine the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large nu...
12/30/2003
6638907Laminin 8 and methods for its use
The present invention provides substantially purified laminin 8, methods for making recombinant laminin 8, cells that express recombinant laminin 8, and methods for using the recombinant laminin 8 to accelerate the healing of injuries to vascular tissue a...
10/28/2003
6632790Laminin 2 and methods for its use
The present invention provides substantially purified laminin 2, methods for making recombinant laminin 2, cells that express recombinant laminin 2, and methods for using the substantially purified laminin 2 to accelerate peripheral nervous system nerve r...
10/14/2003
6620591System for cell-based screening
The invention relates to an optical system for determining the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for specific biological activity. The invent...
09/16/2003
6610852Post-Amadori inhibitors of advanced glycation reactions
The present invention provides novel compounds, pharmaceutical compositions, methods, and kits for inhibiting the conversion of Amadori compounds to post Amadori advanced glycation endproducts, and for treating and preventing chronic tissue damage and dia...
08/26/2003
6335195Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
The present invention provides methods, improved cell culture medium and kits for promoting hematopoietic and mesenchymal stem and lineage-specific cell proliferation and differentiation by growth in the presence of angiotensinogen, angiotensin I (AI); AI...
01/01/2002
6248587Method for promoting mesenchymal stem and lineage-specific cell proliferation
The present invention fulfills a need in the art for methods that promote hematopoietic and mesenchymal stem and lineage-specific cell proliferation and differentiation by growth in the presence of angiotensinogen, angiotensin I (AI), AI analogues, AI fra...
06/19/2001
6239109Method of promoting erythropoiesis
The present invention provides methods, compounds, pharmaceutical compositions, and kits for the augmentation of erythropoiesis by potentiating erythropoietin-induced differentiation with angiotensinogen, angiotensin I (AI), AI analogues, AI fragments and...
05/29/2001
6174665Hormone replacement therapy monitoring
The present invention provides methods for monitoring the effectiveness of hormone replacement therapy in a perimenopausal, early menopausal, or late menopausal woman, comprising testing for hormonal levels in a body fluid of the woman at intervals depend...
01/16/2001
6007980Alpha-3 chain type IV collagen polypeptides
An isolated and substantially pure polynucleotide encoding 238 amino acids of the carboxy terminal end of the triple helical domain and all 233 amino acids of the carboxy terminal noncollageneous domain of the bovine 댓 chain of type IV collagen. An...
12/28/1999
5989835System for cell-based screening
The invention relates to an optical system for determining the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large numbers of compounds for specific biological activity. The invent...
11/23/1999
 
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