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| Number | Title | Issue Date |
| 6399573 | Interleukin-1 receptor antagonist beta (IL-1rabeta) IL-1ra beta polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing IL-1ra beta polypeptides and polynucleotides in the design of protocols for the trea... | 06/04/2002 |
| 6369045 | Phospholipase A2 inhibitors thereof and use of same in diagnosis and therapy The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule incoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibi... | 04/09/2002 |
| 6297022 | Method of identifying agonists and antagonists for tumor necrosis related receptor TR1 The present invention relates to tumor necrosis factor receptor (TNF-R) related polypeptide and its ligand, hereinafter referred to as TR1 and TL3. The invention relates to methods to identify agonists and antagonists of TR1 and TL3.... | 10/02/2001 |
| 6228576 | Hepatitis C virus NS5B truncated protein and methods thereof to identify antiviral compounds The invention provides HCV NS5B polypeptides and DNA (RNA) encoding HCV NS5B polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing HCV NS5B polypeptides to screen for antiviral compound... | 05/08/2001 |
| 6225465 | Process for the aminocarbonylation of benzazepines and benzodiazepines A new process for preparing substituted 7-aminocarbonyl-3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepines is disclosed.... | 05/01/2001 |
| 6187544 | Methods for rapid cloning for full length cDNAs using a pooling strategy The present invention provides a method for high throughput cloning of full length cDNA sequences using a pooling strategy. This method uses a plurality of clone arrays prepared from cDNA libraries which have been preferably enriched for 5 ' mRNA sequence... | 02/13/2001 |
| 5965420 | Human protein kinases hYAK3 hYAK3 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hYAK3 polypeptides and polynucleotides in the design of protocols for the treatment of bon... | 10/12/1999 |
| 5948669 | Rat cathepsin K polynucleotide and polypeptide sequence Rat cathepsin k polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing rat cathepsin k polypeptides and polynucleotides in the design of protocols for ... | 09/07/1999 |
| 5942405 | Therapeutic and screening methods using C3a receptor and C3a Human C3a Receptor polypeptides and DNA (RNA) encoding such C3a Receptor and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such C3a Receptor for the treatment of inflammatory a... | 08/24/1999 |
| 5932702 | Human G-protein coupled receptor Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antag... | 08/03/1999 |
| 5928881 | Method of identifying agonists and antagonist for CC-CKR5 receptor The invention provides a method of screening compounds to identify those which enhance or block the action of CC-CKR5. Further provided are compounds which blcok (antagonists) or enhance (agonists) the action of CC-CKR5.... | 07/27/1999 |
