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| Number | Title | Issue Date |
| 4430355 | Condensed isothiazolo-3 (2H)-one-1-1-dioxides Compounds of the formula ##STR1## wherein X is oxygen or sulfur; R1 is hydrogen, methyl or ethyl; and R2 is methyl or ethyl; and non-toxic, physiologically acceptable salts thereof formed with an inorganic or organic base. The compou... | 02/07/1984 |
| 4427648 | Dipyridamole-containing pharmaceutical form This invention relates to vehicles for the administration of dipyridamole. More specifically, this invention relates to a method of treating cardiovascular disorders in a host in need of such treatment which comprises administering to said host a cardiova... | 01/24/1984 |
| 4424226 | Pyridobenzodiazepinones, pharmaceutical compositions thereof and method of use thereof This invention relates to compounds of the formula ##STR1## wherein R is (1-methyl-4-piperidinyl)methyl, (1-methyl-1,2,5,6-tetrahydro-4-pyridinyl)methyl, 1-methyl-1,2,5,6-tetrahydro-4-pyridinyl, (1-methyl-4-piperidinylidene)methyl, 2,3-dehy... | 01/03/1984 |
| 4424222 | Pyridobenzodiazepinones, pharmaceutical compositions and method of use thereof New pyridobenzodiazepinones of the formula ##STR1## are described wherein X represents oxygen, --NH-- or --NCH3 -- and R represents 1-methyl-4-piperidinyl or 4-methyl-1-piperazinyl group optionally substituted by a methyl group, or a 3�... | 01/03/1984 |
| 4421886 | Stabilizer-lubricant combination of lead compounds and partial esters of pentaerythritol and/or trimethylolpropane with fatty acids for molding compositions based on polyvinyl chloride A stabilizer-lubricant composition for molding materials based on polyvinyl chloride and/or mixed polymers containing mainly vinyl chloride comprising (a) a partial ester of pentaerythritol and/or trimethylolpropane with a fatty acid of 8 to 22 carbon atoms, a... | 12/20/1983 |
| 4421755 | Method of treating coronary heart disease with imidazo(4,5-B)pyridines Pharmaceutical compositions containing, as an active ingredient, a compound of the formula ##STR1## wherein R1 is alkoxy of 1 to 4 carbon atoms, and R2 is (alkyl of 1 to 4 carbon atoms) sulfinyl, or a non-toxic, pharmacologicall... | 12/20/1983 |
| 4420597 | (Meth)acrylates of isocyanuric acid derivatives containing hydroxyl groups and their use as adhesives This invention is directed to esters of isocyanuric acid derivatives. More particularly, this invention is directed to acrylates or methacrylates of isocyanuric acid derivatives containing hydroxyl groups, the preparation of said compounds, and their use ... | 12/13/1983 |
| 4417895 | Treatment of textiles with antimicrobial agents This invention is directed to a process for the antimicrobial treatment of textiles during washing and softening cycles using liquid textile washing agents based upon nonionic tensides and containing fabric-softening quaternary nitrogen compounds, wherein... | 11/29/1983 |
| 4415566 | Cephalosporin derivatives Penicillins and cephalosporins of the formula ##STR1## wherein A is phenyl, 4-hydroxyphenyl, cyclohexyl, cyclohene-1-yl, cyclohexa-1,4-diene-1-yl, 2-thienyl, 3-thienyl, 2-furyl, 3-furyl or 3,4-disubstituted phenyl, where the substituents, which may b... | 11/15/1983 |
| 4414225 | Azepine derivatives and their anti-thrombotic compositions and methods Compounds of the formula ##STR1## wherein n and m are each 1, 2 or 3, and the sum of n+m is 4; R1 is alkyl; alkenyl; unsubstituted, mono- or di-substituted aralkyl; unsubstituted, mono- or di-substituted benzoyl; alkoxycarbonyl; aralkoxyca... | 11/08/1983 |
| 4410527 | Substituted thienobenzodiazepinones and salts thereof Compounds of the formula ##STR1## wherein R is 1-methyl-4-piperididinyl, 4-methyl-1-piperazinyl, or 3 - or 3 -tropanyl, each of which may optionally have another methyl substituent attached to the heterocyclic ring; R1 is hydrogen or alkyl... | 10/18/1983 |
| 4409235 | Substituted 7-(2,6-dibromo-4-methyl-phenyl)-2,3-dihydro-imidazo[1,2-a]imidazoles, compositions and use Compounds of the formula ##STR1## wherein R is hydrogen or methyl, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.... | 10/11/1983 |
| 4409220 | Fused-ring amino-pyrazines as bradycardiac agents Compounds of the formula ##STR1## wherein A and B, which may be the same or different, each represent methylene, (alkyl of 1 to 3 carbon atoms)-methylene, ethylene or (alkyl of 1 to 3 carbon atoms)-ethylene; R1 is hydrogen, alkyl of 1 to 6... | 10/11/1983 |
| 4401667 | Cephalosporins Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl, 3-thienyl or 3,4-dihydroxy-phenyl; Het is 4H-5,6-dioxo-1,2,4-triazin-3-yl, 4-methyl-5,6-dioxo-1,2,4-triazin-3-yl, 1-vinyl-tetrazol-5-yl, 1-allyl-tetrazol-5-yl or... | 08/30/1983 |
| 4400378 | Pharmaceutical composition for the treatment of glaucoma The method of treating glaucoma with compounds of the formula ##STR1## wherein R1 is hydrogen, alkyl of 1 to 4 carbon atoms, hydroxy-(alkyl of 1 to 4 carbon atoms), benzyl, halo-benzyl, methyl-benzyl, methoxy-benzyl or allyl; X is oxygen o... | 08/23/1983 |
| 4394159 | 2-Chloro-3-(phenoxy or phenylthio)-6-6-nitro -anilines This invention is directed to 2-chloro-6-nitro-aniline compounds of the formula ##STR1## wherein A represents hydrogen, a straight or branched alkyl radical having from 1 to 6 carbon atoms a cycloalkyl radical having from 3 to 6 carbon atoms, a ... | 07/19/1983 |
| 4393069 | 8-Arylalkyl-3-phenyl-3-nortropanols and salts thereof Compounds of the formula ##STR1## wherein Ar is ##STR2## R1 is hydrogen, fluorine, bromine, methyl or methoxy; X is .dbd.CO, .dbd.CH--CN, .dbd.CH--OH, --O--, --S--, --NH--, ##STR3## and R is hydrogen, 4-fluoro, 4-chloro, 4-... | 07/12/1983 |
| 4392590 | Eye drop dispensing bottle The invention provides an eye drop dispensing bottle, comprising, in addition to the dispensing opening, an elastic supporting finger by which the bottle may be supported, e.g. at the forehead over the eye, thus achieving an easy and accurate tilting of t... | 07/12/1983 |
| 4388318 | Method of treating endotoxin shock with a pyrimido-pyrimidine derivative The method of treating endotoxin shock with 2,2'-[(4,8-bis(diethylamino)-pyrimido[5,4-d]pyrimidine-2,6-diyl)di-(2-meth oxyethyl)imino]diethanol or a non-toxic, pharmacologically acceptable acid addition salt thereof.... | 06/14/1983 |
| 4388315 | Cephalosporins Cephalosporins of the formula ##STR1## wherein A is phenyl, 4-hydroxyphenyl, cyclohexyl, cyclohexene-1-yl, cyclohexa-1,4-diene-1-yl, 2-thienyl, 3-thienyl, 2-furyl, 3-furyl or 3,4-disubstituted phenyl, where the substituents, which may be identical ... | 06/14/1983 |
| 4385048 | Methods for the treatment of nasal hypersecretion Compositions for the treatment of nasal hypersecretion comprising (8r)-8-isopropyl-3-[(&#b1;)-tropoyl-oxy]-1H, 5H-tropanium bromide in a pharmaceutical formulation suitable for topical application to the nasal cavity; and methods of u... | 05/24/1983 |
| 4381303 | 1,4,9,10-Tetrahydro-pyrazolo [4,3-]pyrido[-3,2-b][1,4]diazepin-10-ones This invention is directed to the compounds of the formula ##STR1## wherein R1 is hydrogen or an alkyl of from 1 to 6 carbon atoms; R2 is an alkyl of from 1 to 3 carbon atoms; R3 is hydrogen or an alkyl of from 1 to 3 carbon at... | 04/26/1983 |
| 4379788 | 2-Phenyl-pyrimidones Compounds of the formula ##STR1## wherein A and B, together with each other and the respective carbon atoms to which they are attached, form a phenyl or pyridine ring; R1 is hydrogen, halogen, amino, nitro, alkyl of 1 to 3 carbon atoms or ... | 04/12/1983 |
| 4378361 | Heterocyclic compounds Compounds of the formula ##STR1## wherein Het is ##STR2## n is an integer from 1 to 4, inclusive, preferably 2 or 3, R1 is H or acyl, R2 is H, R1 O, --NHSO2 R7, --NHCOR8, --N... | 03/29/1983 |
| 4377576 | 5-(Heterocyclic amino-propionyl)-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-ones Compounds of the formula ##STR1## wherein R1 is hydrogen, methyl or ethyl; R2 is hydrogen or chlorine; R3 is hydrogen or chlorine; and R4 is pyrrolidino, piperidino, 2-methyl-piperidino, 2-ethyl-piperidino, 2,6-... | 03/22/1983 |
| 4376760 | Tridecapeptide The tridecapeptide of the formula and the use thereof as a hapten, tracer or antibody.... | 03/15/1983 |
| 4373964 | Assistants for the preparation of pigment pastes and high-concentration, low viscosity pigment pastes In the process for the preparation of high concentration, low-viscosity liquid pigment pastes comprising mixing pigments, a substantially non-volatile liquid organic media, a suspension assistant, and, optionally, fillers, the improvement consisting of us... | 02/15/1983 |
| 4372827 | Novel horizontal diaphragmless electrolyzer A horizontal diaphragmless bipolar electrolyzer comprising a horizontal housing made of electrically insulated material, an anodic or (cathodic) plate at one end of the housing provided with a plurality of blade shaped electrodes vertically arranged along... | 02/08/1983 |
| 4370312 | Decapeptide The decapeptide of the formula and the use thereof as hapten, tracer or antibody.... | 01/25/1983 |
| 4368306 | Process and catalyst for the polymerization of -olefins Poly--olefins, particularly polyethylene, having a broad molecular weight distribution, can be prepared discontinuously or continuously in the gaseous phase or in hydrocarbons as dispersants, at a pressure of from 2 to 40 bar and at a temperature o... | 01/11/1983 |
| 4364944 | Cephalosporins Compounds of the formula ##STR1## wherein Y is hydrogen or methoxy; A is ##STR2## or, when Y is methoxy, also phenyl, 4-hydroxy-phenyl, 2-thienyl, 3-thienyl of 3,4-dihydroxy-phenyl; A' is hydrogen, --COCH2 Cl, --COCH2 Br, ... | 12/21/1982 |
| 4364875 | Process for the preparation of certain diphenyl ethers The method of preparing a compound of the formula ##STR1## wherein R1 is hydrogen, halogen, alkyl of 1 to 8 carbon atoms, trifluoromethyl or acetyl; n is 1 when R1 has all the defined meanings, or 2 or 3 when R1 is ha... | 12/21/1982 |
| 4363766 | Process for the preparation of sulfur-containing N-benzyl-amino acids and esters A process for the preparation of sulfur-containing N-benzyl-amino acids of the formula ##STR1## wherein X and Y, which may be identical to or different from each other, are each hydrogen or halogen; R1 is hydrogen or alkyl of 1 to 4 carbon... | 12/14/1982 |
| 4362738 | Esters and amides containing the 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl moiety Compounds of the formula ##STR1## wherein each X, which may be identical or different from the other X, is oxygen or imino; R1 is hydrogen, fluorine, chlorine or bromine; R2 and R3, which may be identical or different from... | 12/07/1982 |
| 4362725 | Cephalosporins Compounds of the formula ##STR1## wherein A is phenyl, 4-hydroxy-phenyl, 2-thienyl, 2-furyl or 3,4-dihydroxy-phenyl; Y is hydrogen or methoxy; Het is 4H-5,6-dioxo-1,2,4-triazin-3-yl, 4-methyl-5,6-dioxo-1,2,4-triazin-3-yl, 2-methyl-5,6-dioxo-1,2,4-triazin-... | 12/07/1982 |
| 4361575 | Substituted 2-phenylamino-2-imidazolines and salts thereof Compounds of the formula ##STR1## wherein R1, R2 and R3, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, bromine, methyl, trifluoromethyl, hydroxyl or amino; R4 | 11/30/1982 |
| 4361563 | Pyridazinone-substituted benzimidazoles and salts Compounds of the formula ##STR1## wherein R1 is hydrogen; trifluoromethyl; alkyl of 1 to 11 carbon atoms; cycloalkyl of 3 to 7 carbon atoms; hydroxyl; alkoxy of 1 to 6 carbon atoms; mercapto; (alkyl of 1 to 6 carbon atoms)-mercapto; p... | 11/30/1982 |
| 4360024 | Catheter with liquid flow control means A catheter with liquid flow control means having a hub portion and a bore therethrough, where the hub portion is resiliently distortable to close the bore by manual pressure prior to connection of the hub portion to other apparatus, but closure of the bor... | 11/23/1982 |
| 4359468 | Antiallergic N-[4-(indolyl)-piperidino-alkyl]-benzimidazolones Compounds of the formula ##STR1## wherein R1 is hydrogen, halogen or methoxy; R2 is hydrogen or lower alkyl; R3 is hydrogen or lower alkyl; R4 is hydrogen, lower alkyl or alkenyl of 3 carbon atoms; and n is 2 to 6; a... | 11/16/1982 |
| 4357320 | Infectious bronchitis vaccine for poultry Infectious bronchitis (IB) vaccines for poultry derived from at least one novel virus strain of novel infectious bronchitis serotypes, selected from the group consisting of culture Nos. CNCTC A 07/80, CNCTC A 08/80, CNCTC A 09/80, CNCTC A 010/80, CNCTC A ... | 11/02/1982 |
