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| Number | Title | Issue Date |
| 5591645 | Solid phase chromatographic immunoassay A chromatographic test strip comprising a solid support having at least a first portion and a second portion with said portions being in the same plane so as to permit capillary flow communication with each other. The sample is added to the first portion.... | 01/07/1997 |
| 5288477 | Method for prognosticating response to cancer therapy A method for prognosticating the effectiveness of a chemotherapy using monoclonal antibodies and ligand molecules. The putative anti-cancer agent has binding specificity for a oncogenic receptor molecule on the membrane of a cancer cell, such as HER-2/neu... | 02/22/1994 |
| 5234816 | Method for the classification and monitoring of leukemias A method for classifying and monitoring leukemias is disclosed. The method comprises mixing cells from a patient with a plurality of fluorescently labelled monoclonal antibodies, examining the cells by means of flow cytometry, scoring the percent of posit... | 08/10/1993 |
| 5224058 | Method for data transformation A method for the non-linear, non-logrithmic transformation of one or more parameters of data gathered by means of flow cytometry is disclosed wherein the method seeks to maximize the resolution between populations of interest for each parameter while main... | 06/29/1993 |
| 5178858 | Method for prevention of graft versus host disease A method is disclosed for the treatment and prevention of graft versus host disease in man through the combined use of anti-CD8 monoclonal antibodies and a CD4+ cell inactivator.... | 01/12/1993 |
| 5173293 | Anti-T-cell antibodies as adjuvants An antigen/antibody complex is described wherein the antibody functions as an adjuvant. The antibody comprises an anti-lymphocyte antibody. The antigen comprises a hapten, peptide, protein, carbohydrate, virus, bacterium, parasite or other whole microorga... | 12/22/1992 |
| 5156951 | Detecting immunological changes in HIV infected patient samples The present invention comprises a method for detecting immunological changes in blood samples from patients infected with HIV. The method comprises the use of fluorescently labelled monoclonal antibodies against IL-2R (CD25). Other antibodies, including a... | 10/20/1992 |
| 5137809 | Method to determine the composition of bone marrow samples A method and kit for identification of the lineages and stages of hematopoietic cells in a sample wherein the cells are treated with labeled monoclonal antibodies selected to distinguish between each lineage and maturational stages within each lineage.... | 08/11/1992 |
| 5124251 | CD3 .zeta. co-associated complex on CD16- NK cells A novel protein complex is disclosed which is co-associated with CD3.zeta. on CD16- NK cells. A purified form of the protein complex, a gene encoding the protein complex and method of producing the purified protein complex also are disclosed. A... | 06/23/1992 |
| 5108904 | CD44 as a marker for HIV infection A method for discriminating between patients who are seropositive but asymptomatic for HIV infection and AIDS patients is disclosed wherein the fluorescence intensity from CD44+ T cells is measured. Intensity increases as AIDS progr... | 04/28/1992 |
| 5085985 | Monoclonal antibodies and their use in a method for monitoring subsets of activated T cells Monoclonal antibodies which recognize activated T lymphocytes are secreted by hybridomas produced by conventinal fusion and selection methodology following immunization of mice with a human lymphocyte fraction containing T lymphocytes activated by a mitro... | 02/04/1992 |
| 5057413 | Method for discriminating between intact and damaged cells in a sample A method is disclosed for the discrimination between intact and damaged cells in a sample, and more particularly, the method uses a vital nucleic acid dye to selectively stain intact versus damaged cells which then may be counted and sorted by flow cytome... | 10/15/1991 |
| 5055560 | L60: a novel monoclonal antibody L60 is a novel monoclonal antibody that will react with Leu 22. It is equally reactive in formalin, ZnSO4 or Bouin's fixed, paraffin-embedded tissues as well as in frozen tissues.... | 10/08/1991 |
| 5047321 | Method for analysis of cellular components of a fluid A method for multi-parameter analysis of cells in a body fluid sample is described which makes use of a plurality of fluorescence measurements, comprising at least two nucleic acid dyes and at least one fluorescently labelled cell surface marker, and a pl... | 09/10/1991 |
| 5041289 | Method of purging residual tumor cells in vitro with lymphokine activated cytotoxic cells A method is disclosed for removing residual tumor cells from a patient with a neoplastic disorder by treating in vitro cell preparation with lymphokine activated cytotoxic cells.... | 08/20/1991 |
| 4994378 | Method for reducing blood carbon dioxide background in bacterial media by the addition of micelles of saponin and a phospholipid A non-ionic lytic agent, preferably saponin for reducing the background carbon dioxide produced by blood cell metabolism is used in the testing of cultures for the presence of microorganisms. The hemolytic agent saponin is combined with a phospholipid, pr... | 02/19/1991 |
| 4987086 | Method for analysis of subpopulations of cells A method and kit for determination of subsets of leukocytes utilizing flow cytometry analysis techniques.... | 01/22/1991 |
| 4957870 | Detection of Reticulocytes, RNA and DNA Reticulocytes, RNA or DNA are stained with a dye for detection in a flow cytometer. The dye has the formula: ##STR1## Wherein X=O, S, se or C(CH3)2 ; R1 =alkyl having from 1-6 carbons; R2 =alkyl having from 1-6 ... | 09/18/1990 |
| 4945056 | L60: a novel monoclonal antibody L60 is a novel monoclonal antibody that will react with Leu 22. It is equally reactive in formalin, ZnSO4 or Bouin's fixed, paraffin-embedded tissues as well as in frozen tissues.... | 07/31/1990 |
| 4937198 | Novel fluorescent dye A novel fluorescent dye, PUR-1, having the structural formula ##STR1## is disclosed that will preferentially stain nucleic acids.... | 06/26/1990 |
| 4933471 | Xanthene dyes Novel xanthene dyes are disclosed which excite in the range of 450-650 nm and which will emit to the red of fluoroscein. These dyes may be coupled to tagging agents, such as monoclonal antibodies, and used to detect cells in a sample.... | 06/12/1990 |
| 4902613 | Lysing agent for analysis of peripheral blood cells A lysing agent and a method for utilizing the lysing agent in the identification and enumeration of cells of a select subclass of leucocytes is provided. The lysing agent includes formaldehyde, an alkali or alkaline earth salt of a weak acid and a polyhyd... | 02/20/1990 |
| 4885237 | Detection of cellular DNA A method is described for the detection of halodeoxyuridines taken up by cells during DNA synthesis by the use of monoclonal antibodies. The described method also allows the simultaneous detection of cell surface receptors.... | 12/05/1989 |
| 4883867 | Detection of reticulocytes, RNA or DNA Reticulocytes, RNA or DNA are stained with a dye for detection in a flow cytometer. The dye has the formula: ##STR1## Wherein: X=O,S, Se, N -alkyl (having 1-6 carbons) or C (CH3)n ; R1 =alkyl having from 1-6 carbons; ... | 11/28/1989 |
| 4867908 | Method and materials for calibrating flow cytometers and other analysis instruments A method for calibrating an instrument for using that instrument to obtain at least one light-related signal from particles under analysis comprises directing an incident beam of light at calibration particles having one or more known characteristics rela... | 09/19/1989 |
| 4770992 | Detection of specific DNA sequences by flow cytometry A method for detection of DNA sequences. In the method, chromatin (comprising protein and DNA) is contacted with a cross-linking agent for the protein of the chromatin to provide a substantially rigid chromatin particle. The DNA of the chromatin particle ... | 09/13/1988 |
| 4759492 | Pipe aligner A pipe aligner for holding a metal pipe securely for welding which comprises a back, two arms that wrap around the pipe and means to secure the pipes to the arms and back.... | 07/26/1988 |
| 4727020 | Method for analysis of subpopulations of blood cells A method for identifying and enumerating cells of a subclass of blood cells in relation to cells of another subclass of blood cells is provided. In the method a first subclass of blood cells is selectively tagged by incubating an aliquot of a blood sample... | 02/23/1988 |
