Bizarre Patents
Decorative Jeweled Wheel Cover
An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.
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| Number | Title | Issue Date |
| 8163929 | Dihydropyridone amides as P2Xmodulators Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, R1, R2, R3, R4, R5 and R6 are as defined herein. Also disclosed... | 04/24/2012 |
| 8153809 | Dihydropyridone ureas as P2Xmodulators Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of makin... | 04/10/2012 |
| 8153808 | Dihydropyridone amides as P2X7 modulators Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of makin... | 04/10/2012 |
| 8119842 | Process for synthesis of amino-methyl tetralin derivatives Methods for producing a compound of formula k1 or k2 by reducing a dihydronapthalene amide compound of formula i with hydrogen gas in the presence of a ruthenium catalyst of formu... | 02/21/2012 |
| 8119644 | Thiadiazole-substituted arylamides as P2X3 and P2X2/3 antagonists Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted thiadiazolyl, and R2, R3, R4, R5, R6, R... | 02/21/2012 |
| 8101665 | Process for synthesis of tritiated and deuterated thiorphan and acetorphan Methods for preparing tritium or deuterium labeled thiorphan comprising reacting a compound of formula j wherein m is from 1 to 5 and X is halo, with Z2 wherein Z is tritium or deuterium, in the presence of a cat... | 01/24/2012 |
| 8093424 | Tetralin and indane derivatives and uses thereof Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R1 and R2 are as defined herein. Also provided are methods for preparing, compositions com... | 01/10/2012 |
| 8093285 | Aminopiperidinyl derivatives and uses thereof This application discloses aminopiperidinyl compounds of generic Formulae I-II: or pharmaceutically acceptable salts thereof, wherein m, r, Q1, Q2, Q3, R, Ra, R1, R | 01/10/2012 |
| 8093275 | Oxazolone and pyrrolidinone-substituted pryidine amides as P2Xand P2Xantagonists Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, X, Y, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Als... | 01/10/2012 |
| 8084623 | Pyrrolidinyl and piperidinyl ketone derivatives and uses thereof Compounds of the formula: or pharmaceutically acceptable salts thereof, wherein m, n, Ar, R1, R2, Ra and Rb are defined herein. Also provided are pharmaceutical composit... | 12/27/2011 |
| 8048905 | Tetrazole-substituted arylamides as P2Xand P2Xantagonists Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted tetrazolyl, R2 is optionally substituted phenyl, optionally substituted pyridinyl or opt... | 11/01/2011 |
| 8008313 | Methods of using diaminopyrimidine P2Xand P2Xreceptor modulators for treatment of respiratory and gastrointestinal diseases Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): | 08/30/2011 |
| 8003788 | Process for synthesis of phenoxy diaminopyrimidine derivatives A method for preparing a compound of formula k or a salt or solvate thereof, wherein R1 is as defined herein, the method comprising treating a c... | 08/23/2011 |
| 8003099 | Antibodies against human IL17 and uses thereof An antibody binding to IL-17 characterized by binding to the same IL-17 epitope to which monoclonal antibody 3C1 binds, and being of human IgG1 isotype modified in the hinge region at amino acid position 216-240, preferably at amino acid position 220-240, between C | 08/23/2011 |
| 7998963 | Arylpiperazine derivatives and uses thereof Compounds of formula I: or pharmaceutically acceptable salts thereof, wherein Ar is indolyl, indazolyl or dihydroindolyl, and R1, R2, R3 and R4 are as defined herein. Also provide... | 08/16/2011 |
| 7989637 | Triazole-substituted arylamides as P2Xand P2Xantagonists Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted triazolyl, and R2, R3, R4, R5, R6, R7 | 08/02/2011 |
| 7981923 | Tetralin and indane derivatives and uses thereof Compounds of the formula I, II or III: or pharmaceutically acceptable salts thereof, wherein m, n, q, Ar, R1, R2, R3, R4 and R5 are as defined herein. Also pr... | 07/19/2011 |
| 7981914 | Tetrazole-substituted aryl amide derivatives and uses thereof Compounds of the formula: wherein R1, R2, Ar1, Ar2, and n are as defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the subj... | 07/19/2011 |
| 7951920 | Conjugate of an antibody against CCR5 and an antifusogenic peptide The current invention is related to a conjugate comprising one or more antifusogenic peptides and an anti-CCR5 antibody (mAb CCR5) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of the a... | 05/31/2011 |
| 7901901 | Assays for measuring phosphate modification enzyme activity The present invention relates to assays that can measure the activity of enzymes that catalyze phosphate modifications, such as kinases, phosphatases, cyclases and phosphodiesterases. The assays can also be used to identify and screen for substances that modulate th... | 03/08/2011 |
| 7868141 | Anti-OX40L antibodies This invention relates to anti-OX40L antibodies and, in particular, to anti-OX40L antibodies and variants thereof that contain a Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a ben... | 01/11/2011 |
| 7863305 | 3-amino-1-arylpropyl indoles as monoamine reuptake inhibitors Compounds of formula I: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc, Rd | 01/04/2011 |
| 7858654 | Imidazole-substituted arylamides as P2Xand P2Xantagonists Compounds of the formula I: wherein R1 is optionally substituted imidazolyl, and R2, R3, R4, R5, R6, R7 and R8 are as defined herein. A... | 12/28/2010 |
| 7858632 | Diaminopyrimidines as P2Xand P2Xantagonists Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I): | 12/28/2010 |
| 7803830 | 3-amino-1-arylpropyl indoles and AZA-substituted indoles and uses thereof The present invention provides compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb... | 09/28/2010 |
| 7799816 | Imidazolinylmethyl aryl sulfonamide This invention relates to an alpha-1 A receptor partial agonist, which is represented by Formula I: and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions con... | 09/21/2010 |
| 7799797 | Arylsulfonyl naphthalene derivatives and uses thereof Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, q, Ar, R1, R2 and R7 are as defined herein. Also provided are methods for preparing, compositio... | 09/21/2010 |
| 7799796 | Diaminopyrimidines as P2Xand P2Xmodulators Compounds and methods for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the compounds being of formula (I): wherein D, X, R1, R2, R3, R... | 09/21/2010 |
| 7786110 | Thiazole and oxazole-substituted arylamides as P2Xand P2Xantagonists Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is a group of formula A or formula B, and X, R2, R3, R... | 08/31/2010 |
| 7776872 | Diaminopyrimidines as P2Xand P2Xmodulators Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein A, D, E, G, J, X, Y, Z R6, R7 and R8 are as defined herein. Also provided are methods of using the compounds... | 08/17/2010 |
| 7759389 | Chroman derivatives and uses thereof Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R1, R2, R3 and R4 are as defined herein. Also provided are methods for pre... | 07/20/2010 |
| 7754759 | Arylsulfonyl chromans as 5-HTinhibitors Compounds of the formula I: wherein m, n, p, X, Ar, R1, R2, R3, R4 and R5 are as defined herein. Methods of making the compounds and using the compounds for treatment o... | 07/13/2010 |
| 7754721 | Arylpiperazine derivatives and uses thereof Compounds of the formula: or pharmaceutically acceptable salts thereof, wherein m, n, X, Y, Z, Ar, R1, R2, R3, R4, R5, R6 and R7 are def... | 07/13/2010 |
| 7750016 | Hydroxyalkyl substituted pyrido-7-pyrimidin-7-ones Compounds of the Formula: where X1, Ar1, R1, and R2 are as defined herein, and compositions comprising the same. Also provided are methods for using compounds of Formula I in trea... | 07/06/2010 |
| 7741326 | Indole and benzofuran 2-carboxamide derivatives and uses thereof Compounds of formula I or formula II: or pharmaceutically acceptable salts thereof, wherein m, n, p, Ar R1, R2, R4, and R5 are as defined herein. The invention also provides metho... | 06/22/2010 |
| 7723391 | Cyclopropyl aryl amide derivatives and uses thereof Compounds of the formula: wherein Ar1, Ar2, R1 and R2 are as defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the subject ... | 05/25/2010 |
| 7671235 | Tetralin and indane derivatives and uses thereof Compounds of the formula I, II or III: or pharmaceutically acceptable salts thereof, wherein m, n, q, Ar, R1, R2, R3, R4 and R5 are as defined herein. Also pr... | 03/02/2010 |
| 7645764 | Kinase inhibitors and methods for using the same Compounds of formula I: wherein R1, R2, R3 and R4 are as defined herein. Also disclosed are methods of making the compounds, pharmaceutical compositions, methods of using the comp... | 01/12/2010 |
| 7638517 | 3-Amino-1-arylpropyl azaindoles and uses thereof The present invention provides compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein p, Ar, R1, R2, R3, Ra, Rb, Rc | 12/29/2009 |
| 7622462 | Benzazepine derivatives and uses thereof Compounds of the formula: or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ar, R1 and R2 are defined herein. Also provided are pharmaceutical compositions, methods ... | 11/24/2009 |
