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| Number | Title | Issue Date |
| 8119361 | Methods of cleaving DNA with rationally-designed meganucleases Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number ... | 02/21/2012 |
| 8001027 | Apparatus and methods for handling trading data A manually-assisted computer and communications apparatus is provided for periodically fixing a price of a currency or commodity. Successive rate samples of said currency/stock/commodity are received from a plurality of sources (80) over a period of time, rec... | 08/16/2011 |
| 7378086 | Retroviral vector having an ovalbumin promoter Vectors and methods are provided for introducing genetic material into cells of a chicken or other avian species. More particularly, vectors and methods are provided for transferring a transgene to an embryonic chicken cell, so as to create a transgenic hen wherein ... | 05/27/2008 |
| 7231419 | System and method for adaptively selecting and delivering recommendations to a requester A system and method for employing a number of producer modules to produce and deliver recommendations to a requester. Each of the recommendations having associated therewith a confidence level. Each of the producer modules having associated therewith a weighting val... | 06/12/2007 |
| 7033781 | Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating An invention comprising cellular transformation, directed evolution, and screening methods for creating novel transgenic organisms having desirable properties. Thus in one aspect, this invention relates to a method of generating a transgenic organism, such as a micr... | 04/25/2006 |
| 6967023 | Pharmaceutical and cosmetic carrier or composition for topical application A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepa... | 11/22/2005 |
| 6962787 | Diagnostic method for a transmissible spongiform encephalopathy or a prion disease A method is provided for the diagnosis of a transmissible spongiform encephalopathy (TSE) or prion disease in an animal which comprises assaying a sample obtained from said animal to determine the number of hematopoietic cells of the erythroid, megakaryocyte or plat... | 11/08/2005 |
| 6929736 | Compounds, compositions and methods to reduce SOx emissions from FCC units Anionic clay compounds such as hydrotalcite-like compounds can be made by a process wherein a non-hydrotalcite-like compound (or a hydrotalcite-like compound) are heat treated and then hydrated to form hydrotalcite-like compounds having properties (e.g., increased h... | 08/16/2005 |
| 6919592 | Electromechanical memory array using nanotube ribbons and method for making same Electromechanical circuits, such as memory cells, and methods for making same are disclosed. The circuits include a structure having electrically conductive traces and supports extending from a surface of the substrate, and nanotube ribbons suspended by the supports... | 07/19/2005 |
| 6911682 | Electromechanical three-trace junction devices Three trace electromechanical circuits and methods of using same are described. A circuit includes first and second electrically conductive elements with a nanotube ribbon (or other electromechanical elements) disposed therebetween. The nanotube ribbon is movable to... | 06/28/2005 |
| 6902578 | Composite bone graft, method of making and using same The invention is directed to a composite bone graft for implantation in a patient, and methods of making and using the composite bone graft, along with methods for treating patients by implanting the composite bone graft at a site in a patient. The composite bone gr... | 06/07/2005 |
| 6892512 | Automated prescription filling system/method with automated labeling and packaging system/method automated order consolidation system/method Computer assisted systems, methods and mediums for filling one or more orders. One embodiment of the present invention is a system that includes an order consolidation station configured to receive at least one bottle containing pills individually counted and/or at ... | 05/17/2005 |
| 6887466 | Methods for selectively stimulating proliferation of T cells Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule are described. T cell proliferation occurs in the... | 05/03/2005 |
| 6865514 | Post test data processing of a mass storage system A method for measuring mass storage system performance in which the mass storage system has a plurality of disk drive storage elements controlled by a disk drive controller, the controller typically having a cache memory, and the controller receiving commands and da... | 03/08/2005 |
| 6860429 | Security marking system and method for minimizing pirating of data on data media including compact discs and digital versatile discs The present invention is a method and system of marking data media products by introducing a predetermined tracing substance constituting a security marking into a polycarbonate (or polystyrene) composition during the manufacturing stages of the polycarbonate materi... | 03/01/2005 |
| 6840176 | CTP systems having at least one multi-cassette unit and methods for loading plates Two dual-configuration systems for loading plate in a CTP imager; in the first configuration one multi-cassette unit (MCU) serves two CTP imagers and in the second configuration two MCUs serve one CTP imager. ... | 01/11/2005 |
| 6837907 | Method for debriding bone, and bone debrided thereby The invention is directed to a method of debriding bone including incubating the bone and associated soft tissue, with one or more debriding solutions where the debriding solution may include one or more alkaline solutions. Incubation is optionally carried out with ... | 01/04/2005 |
| 6838477 | Lactacystin analogs Described herein are compounds related to lactacystin and lactacystin β-lactone, pharmaceutical compositions containing the compounds, and methods of use. ... | 01/04/2005 |
| 6835721 | Immunomodulatory compounds and methods of use thereof The present invention is directed to novel compounds that function as immunological adjuvants when co-administered with antigens such as vaccines for bacterial and viral diseases, to novel adjuvant formulations which include at least one of the adjuvant compounds of... | 12/28/2004 |
| 6830763 | Continuous acidification demineralization process for producing osteoinductive bone; and osteoinductive bone produced thereby The invention is directed to a process for producing demineralized osteoinductive bone, and demineralized osteoinductive bone produced thereby. The process achieves demineralization of bone by subjecting bone, including for example ground bone, bone cubes, chips, st... | 12/14/2004 |
| 6825396 | Methods for tissue specific synthesis of protein in eggs of transgenic hens Vectors and methods are provided for introducing genetic material into cells of a chicken or other avian species. More particularly, vectors and methods are provided for transferring a transgene to an embryonic chicken cell, so as to create a transgenic hen wherein ... | 11/30/2004 |
| 6802333 | Fluid flow controlling A method and system for controlling the rate of fluid flow. A flow restrictor having known pressure drop and flow rate characteristics provided in a passage through which the fluid, preferably a gas, flows. An upstream pressure sensor determines the pressure of flui... | 10/12/2004 |
| 6804332 | Network based knowledgeable assistant A computer-implemented method of processing communications through a multimedia interface that includes a plurality of interface devices and a plurality of input/output devices. Each of the plurality of interface device is capable of connecting to a different commun... | 10/12/2004 |
| 6794516 | Synthesis of clasto-lactacystin β-lactone and analogs thereof The present invention is directed to an improved synthesis of clasto-lactacystin-β-lactone, and analogs thereof, that proceeds in fewer steps and in much greater overall yield than syntheses described in the prior art. The synthetic pathway relies upon a novel ster... | 09/21/2004 |
| 6794137 | Gene markers useful for detecting skin damage in response to ultraviolet radiation The cellular response to ultraviolet radiation exposure has been characterized on the molecular level through the use of high density gene array technology. Nucleic acid molecules and protein molecules, the expression of which are repressed or induced in response to... | 09/21/2004 |
| 6784177 | Methods using hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate The present invention provides methods of treating and preventing mortality associated with heart failure in an African American patient with hypertension, and improving oxygen consumption, quality of life and exercise tolerance by administering a therapeutically ef... | 08/31/2004 |
| 6784028 | Methods of making electromechanical three-trace junction devices Methods of producing an electromechanical circuit element are described. A lower structure having lower support structures and a lower electrically conductive element is provided. A nanotube ribbon (or other electromechanically responsive element) is formed on an up... | 08/31/2004 |
| 6772961 | Methods and apparatus for spray forming, atomization and heat transfer The present invention is directed to methods and apparatus that use electrostatic and/or electromagnetic fields to enhance the process of spray forming preforms or powders. The present invention also describes methods and apparatus for atomization and heat transfer ... | 08/10/2004 |
| 6775739 | Mirrored drive performance using matching algorithms The invention relates generally to mass storage systems, and in particular to mass storage systems in which stored logical volumes are duplicated in mirrored form. The system includes a method for dynamically maximizing separation of said logical volumes by adjustin... | 08/10/2004 |
| 6775720 | Method and system for configuring a mass storage system for measuring system performance A method for measuring mass storage system performance in which a mass storage system has a plurality of disk drive storage elements controlled by a disk drive controller, the controller typically having a cache memory, and the controller receiving commands and data... | 08/10/2004 |
| 6774052 | Method of making nanotube permeable base transistor A method of making a permeable base transistor (PBT) is disclosed. According to the method, a semiconductor substrate is provided, a base layer is provided on the substrate, and a semiconductor layer is grown over the base layer. The base layer includes metallic nan... | 08/10/2004 |
| D493462 | Drive | 07/27/2004 |
| 6763370 | Method and apparatus for content protection in a secure content delivery system A system for secure delivery of on-demand content over broadband access networks utilizes of servers and security mechanisms to prevent client processes from accessing and executing content without authorization. A plurality of encrypted titles are stored on a conte... | 07/13/2004 |
| 6762202 | Infrared thermography and methods of use The present invention describes rapid noninvasive methods for measuring vasodilation or changes in blood flow in a patient following administration of at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-d... | 07/13/2004 |
| 6761069 | Feedback circuit for micromachined accelerometer An accelerometer had a movable electrode between two fixed electrodes to form a differential capacitor. Drivers provide AC drive signals to the fixed electrodes. The movable electrode is coupled through reading circuitry to an output terminal. In response to a sense... | 07/13/2004 |
| 6759693 | Nanotube permeable base transistor A permeable base transistor (PBT) having a base layer including metallic nanotubes embedded in a semiconductor crystal material is disclosed. The nanotube base layer separates emitter and collector layers of the semiconductor material. ... | 07/06/2004 |
| 6757728 | Content authorization system over networks including searching and reporting for unauthorized use An Internet or other content authorization system consists of an Internet authorization notice in the form of a flag. This flag can be embedded in each original recording at the time of manufacture, such that a primary feature of the flagging system is to prevent In... | 06/29/2004 |
| 6756232 | Method and apparatus for producing compact microarrays The disclosed pin-lifter can selectively lift pins partially out of a printhead of a spotting instrument and thereby prevent the lifted pins from contacting the substrate during any printing. Methods of using pin-lifters to increase the rate of production of compact... | 06/29/2004 |
| 6756103 | Limited play optical devices with interstitial reactive layer and methods of making same Methods and apparatus are provided for making an optically readable storage media in which the reading beam passes through a bonding layer configured with a reactive material that transforms from an optically transparent state to an optically opaque state after expo... | 06/29/2004 |
