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| Number | Title | Issue Date |
| 7494770 | Mesoscale polynucleotide amplification analysis Disclosed are devices for amplifying a preselected polynucleotide in a sample by conducting a polynucleotide polymerization reaction. The devices comprise a substrate microfabricated to define a sample inlet port and a mesoscale flow system, which extends from the i... | 02/24/2009 |
| 7491807 | Gene encoding a DNA repair enzyme and methods of use thereof An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or canc... | 02/17/2009 |
| 7482159 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds The Snail transcription factor has been identified as a repressor of the expression of E-cadherin. The expression of Snail induces invasive and metastatic capacity in tumor cells. This invention presents: a new target protein, Snail, for the identification of new an... | 01/27/2009 |
| 7482126 | Snail, a new marker for tumour invasion and target protein of new antitumoral compounds The Snail transcription factor has been identified as a repressor of the expression of E-cadherin. The expression of Snail induces invasive and metastatic capacity in tumour cells. This invention presents: a new target protein, Snail, for the identification of new a... | 01/27/2009 |
| 7452884 | Methods for inhibiting angiogenesis Novel methods for inhibiting angiogenesis and treating diseases associated with angiogenesis are described. The methods may comprise administering to a patient an effective amount of a 1,2-dithiol-3-thione derivative or metabolite thereof. Preferred compounds for us... | 11/18/2008 |
| 7449571 | Halogenated aminoquinolines and oligonucleotides containing the same Novel synthetic monomers that have the capacity to be assembled into defined oligomers which bind with sequence specificity to duplex Watson-Crick DNA via a triple helix motif are provided. ... | 11/11/2008 |
| 7399804 | Composites and methods for their production Intercalates and exfoliates formed from layered materials and dendritic polymers are disclosed, together with the uses of these materials, e.g. in producing composite materials. The dispersion of layered materials in a dendritic polymer matrix (hyperbranched polymer... | 07/15/2008 |
| 7332159 | Method and composition for inhibiting reperfusion injury in the brain The present invention relates to a method for inhibiting reperfusion injury in the brain. The method involve injecting via the carotid artery or jugular vein an antioxidant-loaded nanoparticle. A nanoparticle formulation containing an inert plasticizer is also provi... | 02/19/2008 |
| 7325604 | Method for enhancing oil production using electricity A method of enhancing oil production from an oil bearing formation includes the steps of providing a first borehole in a first region of the formation and a second borehole in a second region of the formation. A first electrode is positioned in the first borehole in... | 02/05/2008 |
| 7322409 | Method and system for producing methane gas from methane hydrate formations A system for producing gas from a gas hydrate formation includes a first electrode and a second electrode. The first electrode is disposed in proximity of a first region of the formation, and the second electrode is disposed within a second region of the formation. ... | 01/29/2008 |
| 7316914 | Methods and materials relating to gene expression An expression cassette for expressing a nucleic acid of interest derived from the regulatory region of the methylenomycin gene cluster of the SCP1 plasmid of Streptomyces coelicolor A3(2), and related materials and methods. ... | 01/08/2008 |
| 7288574 | Two-phase oxygenated solution and method of use A two-phase mixture is provided having a dissolved gas and a suspension of bubbles in a liquid. Methods for making, maintaining, and using the two-phase mixture are also provided. The gas molecules may be introduced into the liquid at a high velocity under elevated ... | 10/30/2007 |
| 7282232 | Bonded fibrous sheet material The present invention refers to a method of producing a porous bonded fibrous sheet material comprising: (i) treating a porous fibrous substrate which is comprised of cellulosic fibers and which has a moisture content of less than 10% by weight with a gum and a cros... | 10/16/2007 |
| 7265152 | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases The present invention relates to novel benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections ... | 09/04/2007 |
| 7235533 | Compounds and their uses Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or an IPG antagonist thereof. I... | 06/26/2007 |
| 7232663 | Assays employing novel substrates for measuring P450-mediated -dealkylation Methods and compositions for measuring N-dealkylating activity of cytochromes P450 enyzmes are disclosed. ... | 06/19/2007 |
| 7220784 | Substituted stilbenes and their reactions The present invention relates to stilbene and quinone compounds related to combretastatin A-4 and their use as anticancer compounds and prodrugs. The compounds include those with an alkyl group on the double bond of cis or trans-stilbenes, compounds with one or more... | 05/22/2007 |
| 7199122 | Methods for inhibiting angiogenesis Novel methods for inhibiting angiogenesis and treating diseases associated with angiogenesis are described. The methods may comprise administering to a patient an effective amount of a 1,2-dithiol-3-thione derivative or metabolite thereof. Preferred compounds for us... | 04/03/2007 |
| 7198922 | Polyketides and their synthesis A polyketide synthase (“PKS”) of Type I is a complex multienzyme including a loading domain linked to a multiplicity of extension domains. The first extension module receives an acyl starter unit from the loading domain and each extension module adds a further k... | 04/03/2007 |
| 7192716 | Organ transplant rejection and associated conditions Protein markers associated with organ transplant rejection and associated conditions are disclosed, and in particular materials and methods relating to the diagnosis and treatment of acute rejection. Examples of markers include a-Crystallin b-chain Tropomyosin a-cha... | 03/20/2007 |
