Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7192612 | Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of therapeutically effective amount of catechins, a group of polyphenols found in green tea, and Capsicum extra... | 03/20/2007 |
| 6767728 | Composition for enzymatic deinking of waste paper A method and composition for deinking noncontact-printed wastepaper, particularly xerographic and laser-printed paper, and mixtures of contact and noncontact-printed wastepaper, using an enzyme mixture characterized by a high ratio of β-glucosidase activity to filt... | 07/27/2004 |
| 6218525 | Nucleic acid encoding CD28 A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. Novel expression vectors allowing highly efficient construction of mammalian cDNA librari... | 04/17/2001 |
| 6121034 | Coniothyrium minitans xylanase gene Cxy1 The nucleotide sequence of a novel xylanase gene obtained from the soilborne fungus Coniothyrium minitans, and denoted cxy1, is provided. The amino acid sequence of the encoded xylanase enzyme, denoted Cxy1, is also provided.... | 09/19/2000 |
| 6117656 | Cloned genes encoding IG-CD4 fusion proteins and the use thereof The invention relates to a fusion protein which comprises an immunoglobulin of the IgM, IgG1 or IgG3 immunoglobulin class, wherein the variable region of the light or heavy chain has been replaced with CD4 or fragment thereof which is capable of binding t... | 09/12/2000 |
| 6077662 | Virus-like particles, methods and immunogenic compositions The present disclosure provides retrovirus-like particles which comprise retrovirus env proteins, immunogenic compositions comprising retrovirus-like particles, methods for the production of retrovirus-like particles and methods for the protection of an a... | 06/20/2000 |
| 6059113 | Display package with corrugated insert A package for simultaneously protecting and displaying fragile products or items of merchandise, particularly items having the form of slender rods. The package comprises a carton having a window and containing a corrugated insert. The window permits view... | 05/09/2000 |
| 6017532 | Porphyromonas gingivalis arginine-specific proteinase Provided herein is a Porphyromonas gingivalis high molecular weight arginine-specific proteinase comprising a protease component of 50 kD and a hemagglutinin component of about 44 kD as estimated by SDS-PAGE. The proteinase is stimulated by glycine contai... | 01/25/2000 |
| 6017708 | Human Myt1 protein and chimeric proteins derived therefrom The cDNA of the human Myt1 kinase (Myt1Hu), which catalyzes phosphorylation of Cdc2 on Thr 14 and Tyr 15, has been cloned and sequenced. The invention provides isolated, purified and structurally defined DNA encoding Myt1Hu, isolated and purified Myt1Hu p... | 01/25/2000 |
| 6015701 | N-acetylglucosaminyltransferase V proteins and coding sequences The present invention provides substantially purified UDP-N-acetylglucosamine: -6-D-mannoside ଲ-1,6-N-acetylglucosaminyl transferase (GlcNAc T-V; EC 2.4.1.155) proteins and antibodies which specifically bind GlcNAc T-V. The present inven... | 01/18/2000 |
| 6013858 | Mouse lacking heart-muscle adenine nucleotide translocator protein and methods Provided are transgenic mice genetically engineered for a deficiency of the heart-skeletal muscle isoform of the adenine nucleotide translocator protein (Ant1). These mice exhibit histological, biochemical and physiological signs of deficiency in oxidativ... | 01/11/2000 |
| 6004781 | Nucleic acid encoding Ig-CD4 fusion proteins The invention relates to a fusion protein which comprises an immunoglobulin of the IgM, IgG1 or IgG3 immunoglobulin class, wherein the variable region of the light or heavy chain has been replaced with CD4 or fragment thereof which is capable of binding t... | 12/21/1999 |
| 5998701 | Potatoes having improved quality characteristics and methods for their production Potato plants which exhibit reduced levels of glucan L-type tuber phosphorylase (GLTP) or glucan H-type tuber phosphorylase (GHTP) enzyme activity within the potato tuber are provided. The conversion of starches to sugars in potato tubers,... | 12/07/1999 |
| 5998624 | Haloisoquinoline carboxamide Compounds of the invention have the general structure ##STR1## X, Y or Z are, respectively independently, H, F or an isotope thereof, Br or an isotope thereof, I or an isotope thereof, At or an isotope thereof, (R1)W or (R2)V an... | 12/07/1999 |
| 5989897 | Yeast silencing genes proteins and methods The present invention provides the yeast genes SAS2, SAS3 and ESA1 and the proteins encoded thereby. SAS2, SAS3 and ESA1 genes of members of the genus Saccharomyces are provided, particularly the SAS2, SAS3 and ESA1 genes of S. cerevisiae. Also provided a... | 11/23/1999 |
| 5977467 | Frequency display for an automatically tuned stringed instrument This invention is a display system for an automatically tuned stringed instrument displaying, individually or simultaneously, the frequency of each string of the instrument. The system provides for using the display to manually tune the instrument or to i... | 11/02/1999 |
| 5969256 | Modular vibration system A modular vibration system which utilizes interchangeable modules to adapt to any of a wide range of applications and performance characteristics. The vibration system comprises a shaker module, a coupling module, and a fixture module. The shaker module i... | 10/19/1999 |
| 5934036 | Insulated concrete slab assembly An insulated concrete slab assembly for use over expansive soils. A slab is cast in place by pouring concrete into preshaped insulating forms. The forms remain permanently in place and provide insulation to reduce heat transfer through the slab. The shape... | 08/10/1999 |
| 5932715 | Nucleotide sequences encoding a CS2 pilin protein Provided herein is a nucleotide sequence encoding a CS2 pilin protein of enterotoxigenic Escherichia coli. Also provided herein are the nucleotide sequences of coding sequences linked to the CS2 coding sequence, which other coding sequences must be expres... | 08/03/1999 |
| 5919998 | Genetic control of plant hormone levels and plant growth Plant growth and plant growth habit can be controlled without the application of exogenous plant hormones or hormone mimetics using the nucleic acid sequences and methods provided. UDP-Glucose: Indol-3-ylacetyl-glucosyl transferase (IAGlu Transferase) ami... | 07/06/1999 |
| 5910478 | Peptidomimetics inhibiting the oncogenic action of p21 ras The present invention provides peptides, cyclized peptides and peptidomimetics which inhibit the oncogenic and/or transforming activity of the p21 ras protein, pharmaceutical compositions containing at least one of the ras-inhibiting peptides, cyclized pe... | 06/08/1999 |
| 5894682 | Shoe with built-in diagnostic indicator of biomechanical compatibility, wear patterns and functional life of shoe, and method of construction thereof The invention provides a shoe having a built-in wear-indicator device capable of signalling (a) extent of shoe wear, (b) biomechanical compatibility with the user, (c) loss of the ability to cushion and absorb shock, and (d) a need for shoe replacement. T... | 04/20/1999 |
| 5891435 | Methods and compositions for delaying or preventing the onset of autoimmune disease The subject invention concerns compositions and methods useful for the prevention or amelioration of autoimmune diseases. Specifically exemplified are compositions and methods useful in immunizing to prevent insulin dependent diabetes. In a preferred embo... | 04/06/1999 |
| 5892582 | Fabry Perot/fiber Bragg grating multi-wavelength reference A multi-wavelength reference for use in identifying and measuring wave-lengths of radiation from an optical device. The invention provides an interferometer to generate a comb of accurately spaced peaks spanning a selected wavelength range combined with a... | 04/06/1999 |
| 5883048 | Thiol stimulation of root formation Thiol compounds are employed in conjunction with compounds which modulate self proliferation, both as to plants and mammals. The thiol compounds find effect in enhancing the effectiveness of auxin like compounds, either as herbicides or in enhancing root ... | 03/16/1999 |
| 5874242 | Efficient translation in eukaryotic and prokaryotic systems The present disclosure provides sequences and methods for efficient protein synthesis in eukaryotic and prokaryotic host cells.... | 02/23/1999 |
| 5858353 | Insect viruses, sequences, insecticidal compositions and methods Insect viruses capable of killing at least one target insect pest quicker than previously described viruses and DNA sequence conferring that phenotype of faster killing are provided. Further improvement in the speed of killing is obtained when the virus o... | 01/12/1999 |
| 5849898 | CD40 coding sequences A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. The present invention specifically provides the CD40 cDNA sequence.... | 12/15/1998 |
| 5840683 | Peptides inhibiting the oncogenic action of p21 ras The present invention provides peptides and cyclized peptides which inhibit the oncogenic and/or transforming activity of the p21 ras protein, pharmaceutical compositions containing at least one of the ras-inhibiting peptides, cyclized peptides and peptid... | 11/24/1998 |
| 5830731 | Cloning vector, polylinker and methods A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. Novel expression vectors allowing highly efficient construction of mammalian cDNA librari... | 11/03/1998 |
| 5814678 | Chemical reactions in water-in-carbon dioxide microemulsions and control thereof The present invention provides for the regulation of the rate of a chemical reaction within the aqueous micelles within a microemulsion of water in supercritical carbon dioxide. Increase in pressure increases the concentration of an ionized reaction compo... | 09/29/1998 |
| 5804402 | Reagent This invention relates to a reagent for enzymatic determination of an analyte concentration in a patient wherein the degree of oxidation of a coenzyme is measured, characterized in that said reagent is stabilized against oxidation by a coenzyme reduction ... | 09/08/1998 |
| 5794676 | Detachable briefcase organizer The present invention provides a detachable organizer with a fastener for securing the organizer closed and/or for securing the organizer to a target surface, such as the interior surface of the closure flap of a flight case or a litigation briefcase. Alt... | 08/18/1998 |
