Greenblatt; Gary D. - US Patent Attorneys and Agents

Attorney: Greenblatt; Gary D.

Number of patents: 65
Last date: April 10, 2012

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Number	Title	Issue Date
8153677	Substituted pyrazolylamide compounds useful as glucokinase activators Compounds are provided which are phosphonate and phosphinate activators and thus are useful in treating diabetes and related diseases and have the structure wherein is a heteroary...	04/10/2012
8124768	4-pyridinone compounds and their use for cancer Disclosed are compounds of Formula (I): and salts thereof. Also, disclosed are methods of using the compounds in the treatment of proliferative diseases, such as cancer, and to pharmaceutical compositions comprising at leas...	02/28/2012
8067582	Fused heterocyclic compounds useful as modulators of nuclear hormone receptor function Disclosed are fused heterocyclic compounds of Formula (I) or pharmaceutically-acceptable salts or stereoisomers thereof. Also disclosed are methods of using such compounds in the treatment of at least one androgen receptor-associated condition, such as, for example,...	11/29/2011
7989477	Monocyclic heterocycles as kinase inhibitors The present invention is directed to compounds having the formula and methods for using them for the treatment of cancer. ...	08/02/2011
7880004	Met kinase inhibitors The invention is directed to compounds that are useful for the treatment of cancer having the following Formula: ...	02/01/2011
7851489	Pyridinone compounds The invention is directed to pyridinone compounds useful for modulating Met kinase, having the following structure: and is further directed to pharmaceutical compositions comprising the compound; and methods for treating pr...	12/14/2010
7776859	Hexahydroimidazopyrazin-3-one compounds useful as modulators of androgen receptor function The present invention is directed to compounds having the formula (I), and/or pharmaceutically-acceptable salts thereof, useful in the treatment of androgen-receptor associated conditions, wherein Ar is aryl, substituted ar...	08/17/2010
7732613	Met kinase inhibitors The present invention is directed to compounds that are useful for treating cancer having one of the following Formulas: ...	06/08/2010
7718795	Succinoylamino benzodiazepines as inhibitors of aβ protein production This invention relates to novel lactams having the formula (I): to their pharmaceutical compositions and to their methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifica...	05/18/2010
7714138	Monocyclic heterocycles as kinase inhibitors The present invention is directed to compounds having the formula and methods for using them for the treatment of cancer. ...	05/11/2010
7655689	Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds. ...	02/02/2010
7569725	Anthranilic acid derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase 3 Disclosed are anthranilic acid derivatives having Formula (I): and pharmaceutically acceptable salts thereof; and pharmaceutical compositions comprising such compounds. Also disclosed are methods of using such compounds in ...	08/04/2009
7566784	Bicyclic heterocycles as kinase inhibitors The compounds of the instant invention can be used as anticancer agents. More specifically, the invention comprises a compound having Formula I or II, ...	07/28/2009
7550458	Tricycloundecane compounds useful as modulators of nuclear hormone receptor function Tricycloundecanes compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds are disclosed. ...	06/23/2009
7547782	Met kinase inhibitors The present invention is directed to compounds having the formula I or II: including salts thereof, and methods for using them for the treatment of cancer. ...	06/16/2009
7517904	Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds. ...	04/14/2009
7470797	Fused heterocyclic imido and amido compounds Disclosed are fused cyclic compounds, method of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds of formula	12/30/2008
7470693	Oxalamide derivatives as kinase inhibitors The invention is directed to compounds having the following Formula I: and methods of using them for the treatment of proliferative diseases. ...	12/30/2008
7468439	Alkylene bridged sultam compounds useful as modulators of nuclear hormone receptor function Disclosed are sultam compounds of Formula (I) or a pharmaceutically-acceptable salt thereof. Also disclosed are methods of using such compounds in the treatment of at least one nuclear hormone receptor-associated condition,...	12/23/2008
7459562	Monocyclic heterocycles as kinase inhibitors The present invention is directed to compounds having the formula and methods for using them for the treatment of cancer. ...	12/02/2008
7439246	Fused heterocyclic kinase inhibitors In general, the instant invention comprises compounds of Formulas I and II including pharmaceutically acceptable salts thereof. The compounds of the invention are useful as protein kinase inhibitors and therefore are useful...	10/21/2008
7432267	Fused cyclic modulators of nuclear hormone receptor function Disclosed are compounds having the formula (I): including compounds of formulae (Ia) and (Ib): wherein G is an optionally substituted aryl or heterocyclo, L is an optional linker,...	10/07/2008
7417040	Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 Disclosed are fused tricyclic compounds of the following formula I, or an enantiomer, diastereomer, tautomer or pharmaceutically acceptable salt thereof. The disclosed compounds are useful as inhibitors of 17β-hydroxysteri...	08/26/2008
RE40387	Pharmaceutical compositions, dosage forms and methods for oral administration of epothilones The invention relates to methods of increasing the bioavailability of orally administered epothilones. Epothilones administered by the methods of the invention are sufficiently bioavailable to have a pharmacological effect. The invention further relates to pharmaceu...	06/17/2008
7384958	Quinoline inhibitors of cGMP phosphodiesterase Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5. ...	06/10/2008
7378426	Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3 Disclosed are fused heterotricyclic compounds of the following formula I, or an enantiomer, diastereomer, tautomer or pharmaceutically acceptable salt thereof, wherein one of A ring or C ring is a 5-7 membered unsaturated h...	05/27/2008
7342034	Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds. ...	03/11/2008
7291637	Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds. ...	11/06/2007
7244594	Microbial transformation method for the preparation of an epothilone A microbial method for the preparation of an epothilone containing a terminal hydroxyalkyl group, comprising contacting at least one epothilone having a terminal alkyl group with an enzyme or microorganism capable of catalyzing the selective hydroxylation of said al...	07/17/2007
7241899	Methods for the preparation, isolation and purification of epothilone B, and X-ray crystal structures of epothilone B The present invention relates to improved methods for the production, isolation and purification of epothilone B. These methods include, for example, a fermentation process for the production of epothilone B, isolation via adsorption onto a resin, and subsequent pur...	07/10/2007
7235669	Epothilone side components The invention concerns compounds which can be obtained by fermenting DSM 6773, especially epothilones A1, A2, A8, A9, B10, C1, C2, C3, C4, C5, C6, C7, C8, C9, D1, D2, D5, G1, G2, H1, H2, I1, I2, I3, I4, I5, I6 and K and trans-epothilones C1 and C2. ...	06/26/2007
7235563	Spirocyclic compounds useful as modulators of nuclear hormone receptor function Spirocyclic compounds, methods of using such spirocyclic compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds are disclosed. ...	06/26/2007
7179531	Polymer particles having select pendant groups and composition prepared therefrom Polymer particles having select functional or absorbing groups are provided. The polymer particles are useful for preparing organic-inorganic composite particles that are suitable for providing dried coatings with improved hiding. Aqueous compositions containing the...	02/20/2007
7172884	Methods for the preparation, isolation and purification of epothilone B, and x-ray crystal structures of epothilone B The present invention relates to improved methods for the production, isolation and purification of epothilone B. These methods include, for example, a fermentation process for the production of epothilone B, isolation via adsorption onto a resin, and subsequent pur...	02/06/2007
7157595	Degradation of epothilones According to one embodiment the invention concerns a process for a degradation of an epothilone C or a epothilone D, wherein an epothilone C or epothilone D is subjected to an olefin metathesis in the presence of ethylene and subsequently an optional ester hydrolysi...	01/02/2007
7153879	Polymorphs of an epothilone analog There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula ...	12/26/2006
7125899	Epothilone derivatives The present invention relates to epothilone derivatives, having the following formula: in which the variables G, W, Q, X, Y, B1, B2, Z1, Z2, and R1–R7...	10/24/2006
7105593	Aqueous polymer blend composition An aqueous polymer blend composition containing particles of a first polymer and particles of a second polymer with preferred molecular weight ranges is provided. Coatings prepared from the aqueous polymer blend composition may be employed as coatings which have wat...	09/12/2006
7101921	Polymer composition A polymer composition including polymer particles containing a first polymer and a second polymer is disclosed. The first polymer has a crosslinked core and has a glass transition temperature in the range of −30° C. to 100° C. The second polymer containing selec...	09/05/2006
7091275	Aqueous polymeric composition containing polymeric nanoparticles and treatments prepared therefrom An aqueous polymeric composition containing select polymeric nanoparticles is provided. The select polymeric nanoparticles contain as polymerized units at least one multiethylenically unsaturated monomer and at least one water soluble monomer; and have a mean diamet...	08/15/2006

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Attorney: Greenblatt; Gary D.