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| Number | Title | Issue Date |
| 6281330 | Multimeric forms of members of the steroid/thyroid superfamily of receptors with the ultraspiracle receptor In accordance with the present invention, it has been discovered that various members of the steroid/thyroid superfamily of receptors can interact with the insect-derived ultraspiracle receptor, to form multimeric species. Accordingly, the interaction of ... | 08/28/2001 |
| 6278040 | Receptor-deficient mice and cell lines derived therefrom, and uses thereof In accordance with the present invention, there are provided targeted loss of function mutant mice which express less than endogenous levels of at least one member of the steroid/thyroid superfamily of receptors in at least one specific tissue type. For e... | 08/21/2001 |
| 6211320 | Low viscosity acrylate monomers formulations containing same and uses therefor In accordance with the present invention, there are provided low viscosity acrylate monomers, and compositions based on same having low moisture resistance (and, hence are much less prone to give rise to "popcorning"), excellent handling properties (i.e.,... | 04/03/2001 |
| 6166287 | Corticotropin-releasing factor overproducing transgenic mice In accordance with the present invention, there are provided CRF overproducing transgenic mice which exhibit endocrine abnormalities involving the hypothalamic-pituitary-adrenal axis, such as elevated plasma levels of ACTH and glucocorticoids. The transge... | 12/26/2000 |
| 6162896 | Recombinant vertebrate activin receptors In accordance with the present invention, there are provided novel receptor proteins characterized by having the following domains, reading from the N-terminal end of said protein: an extracellular, ligand-binding domain, a hydrophobic, trans-membrane domain, ... | 12/19/2000 |
| 6027875 | Receptor infection assay The present invention relates to improvements in a bioassay useful for identifying materials that function as ligands for a hormone or hormone-like receptor protein measured by means of induction of reporter DNA driven by a promoter of a hormone response ... | 02/22/2000 |
| 6005086 | Farnesoid activated receptor polypeptides, and nucleic acid encoding the same Farnesyl pyrophosphate, the metabolically active form of farnesol, is a key precursor in the synthesis of cholesterol, carotenoids, steroid hormones, bile acids and other molecules involved in cellular growth and metabolism. A nuclear receptor has been id... | 12/21/1999 |
| 5997904 | Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof In accordance with the present invention, there are provided stabilized total nutrient admixture (TNA) compositions which are useful for the in vivo parenteral delivery of pharmacologically acceptable lipids or fats, as well as methods for the preparation... | 12/07/1999 |
| 5922761 | Methods for in vivo reduction of iron levels and compositions useful therefor In accordance with the present invention, there are provided methods for the in vivo reduction of free iron ion levels in a mammalian subject. The present invention employs a scavenging approach whereby free iron ions are bound in vivo to a suitable physi... | 07/13/1999 |
