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Patent No. 6049912

Mountable Printable Placard With Headband

A resilient headband in a shape for being mounted on the head of the user. The headband is equipped with a longitudinal slotted member for holding a placard.

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Attorney: Gray Cary Ware & Freidenrich LLP, Haile; Lisa A.


Number of patents: 107
Last date: March 04, 2003

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NumberTitleIssue Date
6528249Protein activity screening of clones having DNA from uncultivated microorganisms
Disclosed is a process of screening clones having DNA from an uncultivated microorganism for a specified protein, e.g. enzyme, activity by screening for a specified protein, e.g. enzyme, activity in a library of clones prepared by (i) recovering DNA from ...
03/04/2003
6511811Protein kinase C antagonist related to insulin receptor
Methods and compositions are provided for the treatment of insulin-resistance through the inhibition of protein kinase C-mediated phosphorylation of the amino acid residue Ser1270 of the insulin receptor. Methods for testing candidate compounds...
01/28/2003
6498147Suppression of nuclear factor-.kappa.b dependent processes using oligonucleotides
Antisense oligonucleotides which hybridize with nuclear factor-.kappa. B(NF-.kappa. B) mRNA and methods of using these oligonucleotides....
12/24/2002
6495332Methods and compositions for ameliorating the symptoms of sepsis
The present invention concerns a method of treating sepsis comprising administering a therapeutically effective amount of anti-CD14 antibody molecules. A therapeutic composition comprising anti-CD14 antibody molecules in a pharmaceutically acceptable exci...
12/17/2002
6489145Method of DNA shuffling
Disclosed is a method of producing random polynucleotides by introducing two or more related polynucleotides into a suitable host cell such that a hybrid polynucleotide is generated by recombination and reductive reassortment. Also provided are vector and...
12/03/2002
6479258Non-stochastic generation of genetic vaccines
This invention provides methods of obtaining vaccines by use of non-stochastic methods of directed evolution (DirectEvolution™). These methods include non-stochastic polynucleotide site-satuaration mutagenesis (Gene Site Saturation Mutagenesis™) and n...
11/12/2002
6465429Antimicrobial cationic peptides
A novel class of cationic peptides having antimicrobial activity is provided. Examples of such peptides include [NH2 ]kWKSFIKKLTTAVKKVLTTGLPALIS[COOH] (SEQ ID NO:1) and [NH2 ]KWKSFIKKLTSAAKKVVTTAKPLISS[COOH] (SEQ ID NO:2). Also provi...
10/15/2002
6462190Polynucleotides and kits for detection of an age-related mutation
Provided are polynucleotide sequences useful in detecting age related mutations in a subject as well as methods to identify mutations in mitochondrial sequences....
10/08/2002
6455254Sequence based screening
Provided is a method of obtaining a nucleic acid profile of a sample. The method includes creating a DNA library from a plurality of nucleic acid sequences of a mixed population of organisms and sequencing at least one clone in the DNA library. The sequen...
09/24/2002
6451569Synthetic molecules that specifically react with target sequences
The present invention features biarsenical molecules. Target sequences that specifically react with the biarsenical molecules are also included. The present invention also features kits that include biarsenical molecules and target sequences. Tetraarsenic...
09/17/2002
6444206Methods and compositions for inhibiting CD14 mediated cell activation
This invention provides hybridoma cell lines producing monoclonal antibodies which inhibit CD14 mediated cell activation. Monoclonal antibodies produced by these cell lines also are provided. The antibodies are useful for the detection of the presence of ...
09/03/2002
6444661Detection and treatment of duplex polynucleotide damage
Duplex polynucleotides containing damage or errors are detected with hindered intercalating compounds which are capable of intercalating only in the presence of such damage or error. Conditions characterized by the presence of polynucleotide errors or dam...
09/03/2002
6440668Method of DNA shuffling with polynucleotides produced by blocking or interrupting a synthesis or amplification process
Disclosed is a process of performing Sexual PCR which includes generating random polynucleotides by interrupting or blocking synthesis or amplification process to slow or halt synthesis or amplification of at least one polynucleotides, optionally amplifyi...
08/27/2002
6436673Polynucleotides encoding a novel neuronal cell growth factor
A novel neuronal cell growth factor, neuronal-activity regulated pentraxin, Narp, is provided, as well as polynucleotides encoding Narp. Narp is useful for induction of dendritic neurite outgrowth as well as promotion of neuronal migration. Methods for tr...
08/20/2002
6403374Long wavelength engineered fluorescent proteins
Engineered fluorescent proteins, nucleic acids encoding them and methods of use are provided....
06/11/2002
6388076Protein tyrosine phosphatase-inhibiting compounds
Y--X--C(R').dbd.C(R")COOR'" (A1) The present invention relates to novel protein tyrosine phosphatase modulating compounds having the general structure shown in Formula (A1), to methods for their preparation, to compositions comprising the compounds, to t...
05/14/2002
6380358Guanidinylation reagents
Trisubstituted N-protected guanidines and methods for use as guanidinylating reagents to yield N-protected guanidine derivatives....
04/30/2002
6368798Screening for novel bioactivities
Disclosed is a process for identifying clones having a specified enzyme activity by screening for the specified enzyme activity in a library of clones prepared by (i) selectively isolating target nucleic acid from nucleic acid derived from at least one mi...
04/09/2002
6368844Glycosidase enzymes
A thermostable glycosidase enzymes derived from various Thermococcus, Staphylothermus and Pyrococcus organisms is disclosed. The enzymes are produced from native or recombinant host cells and can be utilized in the food processing industry, pharmaceutical...
04/09/2002
6358709End selection in directed evolution
This invention provides methods of obtaining novel polynucleotides and encoded polypeptides by the use of non-stochastic methods of directed evolution (DirectEvolution™). A particular advantage of end-selection-based methods is the ability to recover fu...
03/19/2002
6350369Method and system for determining analyte activity
Chemical sensors for detecting the activity of a molecule or analyte of interest is provided. The chemical sensors comprise and array or plurality of chemically-sensitive resistors that are capable of interacting with the molecule of interest, wherein the...
02/26/2002
6348329Nucleic acids encoding rat connective tissue growth factor (CTGF) and methods of use
The present invention provides rat connective tissue growth factor (CTGF), means for producing CTGF and therapeutic methods for using CTGF or derivatives therof....
02/19/2002
6349160Detector and screening device for ion channels
The present invention is relates to an optical fiber assembly which may be used in an optical detection system. The optical fiber assembly may comprise a trifurcated cable and a ball lens in optical communication with the trifurcated cable. The trifurcate...
02/19/2002
6347247Electrically induced vessel vasodilation
The invention provides methods for inducing or increasing the vasodilation of a vessel. The invention further provides methods for inducing or increasing the flow of fluid through a vessel. An electrical impulse is applied to the vessel in order to induce...
02/12/2002
6342379Detection of transmembrane potentials by optical methods
Methods and compositions are provided for detecting changes in membrane potential in membranes biological systems. In one aspect, the method comprises; a) providing a living cell with a first reagent comprising a charged hydrophobic molecule which is typi...
01/29/2002
6342595Oncoprotein protein kinase
The present invention provides an isolated polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set fort in SEQ ID NO: 10 or conservative variations thereof. The invention also provides a method for producing a pepti...
01/29/2002
6335179Directed evolution of thermophilic enzymes
Thermostable enzymes are subjected to mutagenesis to produce a thermophilic enzyme which is stable at thermophilic temperature and which has increased activities at least two-fold higher than the activity of the wild-type thermostable enzyme at lower temp...
01/01/2002
6335435Human gene RecQ4 encoding helicase
A gene encoding: (a) a protein comprising an amino acid sequence of SEQ ID NO: 2; or (b) a protein having deletion, substitution or addition of at least one amino acid residue in the amino acid sequence of SEQ ID NO: 2, which has a helicase activity....
01/01/2002
6331406Human enbryonic germ cell and methods of use
Primordial germ cells extracted from post blastocyst human embryos, such as from the gonadal ridges of a 8-11 week LMP human embryo, are disclosed. The primordial germ cells are cultured in long term culture (more than 30 days) resulting in cells that res...
12/18/2001
6329506Template-assisted triple helical collagen-like structures
Synthetic collagen in triple helical conformation and comprising amino acid chains of repeating trimers of highly populated collagen sequences as well as those sequences wherein the proline or hydroxyproline residue is replaced with a peptoid residue. The...
12/11/2001
6329187Endoglucanases
A purified thermostable enzyme is derived from the archael bacterium AEPII1a. The enzyme has a molecular weight of about 60.9 kilodaltons and has cellulase activity. The enzyme can be produced from native or recombinant host cells and can be used to aid i...
12/11/2001
6288048Cholesterol and hedgehog signaling
The present invention sterol-modified hedgehog polypeptides and functional fragments thereof. Methods of identifying compositions which affect hedgehog activity based on inhibition of cholesterol modification of hedgehog protein are described. In one aspe...
09/11/2001
6284461Use of inhibitors in reporter assays
The present invention relates to methods for increasing the signal-to-noise ratio of an enzyme assay by contacting a sample comprising a membrane compartment with an inhibitor of an enzyme, contacting the sample with a substrate for the enzyme, and determ...
09/04/2001
6281332Hedgehog-derived polypeptides
The present invention provides two novel polypeptides, referred to as the "N" and "C" fragments of hedgehog, or N-terminal and C-terminal fragments, respectively, which are derived after specific cleavage at a G.dwnarw. CF site recognized by th...
08/28/2001
6268188Transaminases and aminotransferases
Thermostable transaminase and aminotransferase enzymes derived from various ammonife and aquifex organisms are disclosed. The enzymes are produced from native or recombinant host cells and can be utilized in the pharmaceutical, agricultural and other indu...
07/31/2001
6265171Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguish modified methylated and non-methylated nucleic acids
The present invention provides a method for detecting a methylated CpG-containing nucleic acid present in a specimen by contacting the specimen with an agent that modifies unmethylated cytosine and amplifying the CpG-containing nucleic acid using CpG-spec...
07/24/2001
6266560Electrically assisted transdermal method and apparatus for the treatment of erectile dysfunction
A non-invasive method is provided for treating erectile dysfunction using electroporation enhanced with delivery of a vasoactive or androgenic composition applied to the penis which affords an alternative treatment for patients afflicted with erectile dys...
07/24/2001
6262235Leptospiral outer membranes protein, LipL46
An antigenic preparation is provided containing an outer membrane protein associated with pathogenic strains of Leptospira. The protein has been designated "LipL46" for "lipoprotein from Leptospira" and because the isolated polypeptide migrates to a posit...
07/17/2001
6235470Detection of neoplasia by analysis of saliva
Methods for detection of a cell proliferative disorder, such as cancer, are provided utilizing analysis of target mutant nucleic acids in saliva specimens are described. The presence of target mutant nucleic acids is indicative of a neoplastic disorder of...
05/22/2001
6231852Method for reducing BCL-2 expressing cells resistance to death
Methods for controlling cell death when the cell is exposed to one or more potentially lethal cellular insults. In one method, cell death is inhibited by introducing a reactive oxygen species limiter into the cell which prevents the build up of lethal lev...
05/15/2001
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