Bizarre Patents
User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8084576 | Cancer associated glucose transporter 8 variant The present invention provides the amino acid and nucleic acid sequences of heavy chain and light chain complementarity determining regions of a cancer specific antibody. In addition, the invention provides cancer specific antibodies and immunoconjugates comprising ... | 12/27/2011 |
| 8026055 | Materials and methods for prognosing lung cancer survival The invention provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups. The invention also includes kits for use in the methods of the invention. ... | 09/27/2011 |
| 7956162 | Cancer-associated antigen The present invention provides a novel cancer-associated antigen that can be used in the treatment and diagnosis of cancer. Further, the invention provides amino acid and nucleic acid sequence of the novel antigen, binding proteins, and immuno-conjugates. The invent... | 06/07/2011 |
| 7947265 | Fusion proteins and methods for modulation of immune response A fusion protein comprising GM-CSF and IL-15 is described. The fusion protein has unexpected immune suppressive properties and is useful in a variety of therapeutic applications. ... | 05/24/2011 |
| 7932085 | Modified leukotoxin gene and protein The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, pr... | 04/26/2011 |
| 7902151 | Methods and compositions for modulating immunity Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a CD200 protein or a nucleic acid encoding a CD200 protein. The methods are useful in preventing graft rejection, fetal loss, autoimmune ... | 03/08/2011 |
| 7887798 | Methods of treating cancer by administering antibodies to CD200 Methods and compositions for regulating immunity are disclosed. For enhancing an immune response, agents that inhibit OX-2 are administered. Such methods are useful in treating cancer. For suppressing an immune response, an OX-2 protein or a nucleic acid encoding an... | 02/15/2011 |
| 7868153 | Cinnamic acid 4-hydroxylase After-cooking darkening is a gray-black discoloration of the potato tuber, formed after cooking by the oxidation of an iron-chlorogenic acid complex. Cinnamic acid 4-hydroxylase (C4H) is a key enzyme involved in the biosynthesis of chlorogenic acid. The full-length ... | 01/11/2011 |
| 7833785 | Method for chemical dissociation of cells from physical surfaces The invention provides a novel method of dissociating anchorage independent and dependent cell aggregates. The invention also includes the cells resulting from the methods of the invention and the use of the cells in various applications requiring the generation of ... | 11/16/2010 |
| 7790170 | Modified leukotoxin protein The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, pr... | 09/07/2010 |
| 7732564 | Serum tumor marker in rodent prostate cancer models The present invention relates to a rodent serum marker for prostate cancer comprising b-microseminoprotein (PSP94) and diagnostic methods thereof. The present invention also relates to a recombinant sequence to raise a ligand of a specific binding affinity to a rode... | 06/08/2010 |
| 7723047 | Method for the discrimination and isolation of mammary epithelial stem and colony-forming cells The present invention relates to an improved method that permits the differential isolation of mouse mammary stem cells and colony forming cells (CFCs). The method involves depletion of non-epithelial cells from freshly dissociated mouse mammary tissue by incubation... | 05/25/2010 |
| 7666628 | Preparation of heterologous proteins on oil bodies The present invention relates to the use of a class of genes called oil body protein genes that have unique features. The discovery of these features allowed the invention of methods for the production of recombinant proteins wherein a protein of interest can be eas... | 02/23/2010 |
| 7638285 | Method of the discrimination and isolation of mammary epithelial stem and colony-forming cells The present invention relates to an improved method that permits the differential isolation of mouse mammary stem cells and colony forming cells (CFCs). The method involves depletion of non-epithelial cells from freshly dissociated mouse mammary tissue by incubation... | 12/29/2009 |
| 7575925 | Cell preparations comprising cells of the T cell lineage and methods of making and using them The invention relates to cell preparations comprising cells of the T cell lineage, methods for preparing same, and uses of the cell preparations. ... | 08/18/2009 |
| 7553811 | Methods and compositions for modulating immunity Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a CD200 protein or a nucleic acid encoding a CD200 protein. The methods are useful in preventing graft rejection, fetal loss, autoimmune ... | 06/30/2009 |
| 7553661 | Stromal antigen-presenting cells and use thereof There is provided a stromal antigen-presenting cell capable of antigen presentation in the context of MHC II. When stimulated with IFNγ the stromal cell expresses B7-H1 and/or CD80. These stromal cells can be used to generate an immune response in an animal. ... | 06/30/2009 |
| 7547821 | Methods for the production of insulin in plants Commercial production of human insulin can be affected via transgenic expression in plant seeds. Thus, levels of insulin accumulation exceeding 0.1% of total cellular protein can be achieved recombinantly, through expression of the insulin with a single-chain antibo... | 06/16/2009 |
| 7531325 | Method for cleavage of fusion proteins An improved method for recovering recombinantly produced polypeptides is described. The method involves expressing the recombinant polypeptide as a fusion protein with a pro-peptide. The pro-peptide-polypeptide fusion protein can be cleaved and the recombinant polyp... | 05/12/2009 |
| 7524500 | Method of stimulating stem cells Methods and compositions for stimulating the growth, proliferation, differentiation and/or mobilization of stem and/or progenitor cells are described. The method involves administering an effective amount of a substance which can activate the CD163 hemoglobin scaven... | 04/28/2009 |
| 7501265 | Method for producing and cleaving a fusion proteins with an n-terminal chymosin pro-peptide An improved method for recovering recombinantly produced polypeptides is described. The method involves expressing the recombinant polypeptide as a fusion protein with a pro-peptide. The pro-peptide-polypeptide fusion protein can be cleaved and the recombinant polyp... | 03/10/2009 |
| 7452536 | Methods of treating cancer by administering antibodies to CD200 Methods and compositions for regulating immunity are disclosed. For enhancing an immune response, agents that inhibit OX-2 are administered. Such methods are useful in treating cancer. For suppressing an immune response, an OX-2 protein or a nucleic acid encoding an... | 11/18/2008 |
| 7407762 | Diagnosis of gynecological neoplasms by detecting the levels of oviduct-specific glycoprotein The present invention provides a method for detecting cancer in a patient. A sample from the patient is provided, and the level of oviduct-specific glycoprotein (OGP) in the sample is determined and compared to a control sample. Increased levels of OGP in the sample... | 08/05/2008 |
| 7393637 | Methods for detecting cancer and monitoring cancer progression Mutant BNIP3 plays a functionally important role in the development of solid tumors and in resistance to chemotherapy and radiation treatments. The invention relates to methods of detecting cancer, methods of monitoring the progression of cancer, methods of identify... | 07/01/2008 |
| 7390936 | Commercial production of chymosin in plants A method for the commercial production of chymosin which involves the recombinant expression of chymosin in plant seeds, that enables chymosin to accumulate to at least 0.5% (w/w) of total seed protein is described. An improved method for the isolation of chymosin f... | 06/24/2008 |
| 7387897 | Tetrameric antibody complexes for blocking non-specific labeling of antigens A method for preventing or inhibiting non-specific binding reactions between a detection reagent and an antigen in an immunological assay is described. The method involves using tetrameric antibody complexes that can bind to the antigen and are comprised of two mono... | 06/17/2008 |
| 7375186 | Ricin-like toxin variants for treatment of cancer, viral or parasitic infections The present invention provides a protein having an A chain of a ricin-like toxin, a B chain of a ricin-like toxin and a heterologous linker amino acid sequence, linking the A and B chains. The linker sequence contains a cleavage recognition site for a disease specif... | 05/20/2008 |
| 7368535 | CD200 receptors The present invention relates to CD200 receptor isoforms and modulators thereof and their use in methods of immune modulation and pharmaceutical compositions. ... | 05/06/2008 |
| 7348008 | Ricin-like toxins for treatment of cancer The present invention provides a protein having chain of a ricin-like toxin, a B chain of a ricin-like toxin and a novel heterologous linker amino acid sequence, linking the A and B chains. The linker sequence contains a cleavage recognition site for a specific prot... | 03/25/2008 |
| 7332587 | Oil bodies and associated proteins as affinity matrices A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetical... | 02/19/2008 |
| 7316932 | Method for separating cells The present invention is related to a method for separating a first population of cells from a second population of cells in a sample by discontinuous density gradient separation using dense particles to target the first population of cells and a density separation ... | 01/08/2008 |
| 7304151 | Modified leukotoxin gene and protein The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, pr... | 12/04/2007 |
| 7291330 | MD-1 inhibitors as immune suppressants Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of an agent that inhibits MD-1 with or without an OX-2 protein or a nucleic acid encoding an OX-2 protein. The methods are useful in prevent... | 11/06/2007 |
| 7267959 | Drug target within the sulfonylurea receptor It has been found that syntaxin binds and regulates the nucleotide binding folds (NBFs) of sulfonylurea receptors (SURs) in a ATP- and ADP-dependent manner. The present invention therefore provides methods for identifying compounds that effect the binding between a ... | 09/11/2007 |
| 7247715 | Ricin-like toxin variants for treatment of cancer, viral or parasitic infections The present invention provides a protein having an A chain of a ricin-like toxin, a B chain of a ricin-like toxin and a heterologous linker amino acid sequence, linking the A and B chains. The linker sequence contains a cleavage recognition site for a disease specif... | 07/24/2007 |
| 7238352 | Methods and compositions for modulating tumor growth Methods and compositions for regulating immunity are disclosed. For enhancing an immune response, agents that inhibit OX-2 are administered. Such methods are useful in treating cancer. For suppressing an immune response, an OX-2 protein or a nucleic acid encoding an... | 07/03/2007 |
| 7223729 | Methods of treating allergy by administering a CD200 protein Methods and compositions for inducing immune suppression are disclosed. The methods involve administering an effective amount of a CD200 protein or a nucleic acid encoding a CD200 protein. The methods are useful in preventing graft rejection, fetal loss, autoimmune ... | 05/29/2007 |
| 7205386 | Truncated CD200 A truncated form of the full-length, immunosuppression-inducing molecule, CD200, CD200tr, was expressed in CHO cells and the transduced cells used to produce mAbs to CD200tr. These mAbs detect simultaneous expression of full-length CD200 and CD... | 04/17/2007 |
| 7196185 | Bovine germline D-genes and their application The present invention relates to a bovine VDJ cassette (BF1H1) that provides the novel ability to develop chimeric immunoglobulin molecule capable of incorporating both linear T cell epitope(s) (CDR1H and CDR2H) as well as conformational B cell epitope(s) (exception... | 03/27/2007 |
| 7196243 | Transgenic animal containing CD200 and uses therefor The present invention is directed toward a transgenic non-human animal and uses thereof, wherein each of the cells of the animal contain a transgene comprising a nucleic acid sequence encoding CD200. ... | 03/27/2007 |
