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Attorney: Grassler; Frank P., DiPrima; Joseph F.


Number of patents: 8
Last date: April 13, 1993

NumberTitleIssue Date
52024348a-aza-8a-homoerythromycin lactams
Lactams of the general structural formula: ##STR1## wherein R is hydrogen or C1-10 alkyl. These compounds are macrolides useful as antibiotics and as intermediates for the synthesis of other macrolide antibiotics....
04/13/1993
51891598a-AZA-8a-homoerythromycin cyclic iminoethers
Cyclic iminoethers of the general structural formula wherein one of the R groups is hydrogen and the other R group represents a bond between the oxygen atom at C-6 or C-12 and the imino carbon at C-9; ##STR1## These compounds are macrolides useful as...
02/23/1993
51751593-substituted-1,4-benzodiazepines as oxytocin antagonists
Compounds of Formula I are antagonists of oxytocin and are useful in the treatment of preterm labor and dysmenorrhea, and for stoppage of labor prepatory to Caesarean delivery. ##STR1##...
12/29/1992
51515211-aminoethyl phosphonic acid derivatives
New phosphonic acid derivatives are described which display antibacterial activity....
09/29/1992
5147868Thienamycin renal peptidase inhibitors
Novel chemical compounds are provided which selectively inhibit the metabolism of dipeptidase (E.C.3.4.13.11) and therefore are useful in combination with antibacterial products. These chemical compounds are z-2-acylamino-3-monosubstituted propenoates....
09/15/1992
5147867Phosphorus containing enzyme inhibitors
Dipeptide mimics which contain phosphorus and their pharmaceutical use and preparation are disclosed. The compounds have dehydropeptidase (DHP) enzyme inhibitor activity....
09/15/1992
5145990Phosphorous containing dhp enzyme inhibitors
Compounds of the formula: ##STR1## wherein R1 is C2- C12 linear or branched unsubstituted alkyl; C1- C12 linear or branched substituted alkyl; C2 -C12 linear or branched mon...
09/08/1992
5143908Antibacterial agents and potentiators of carbapenem antibiotics
New 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids are described which display antibacterial activity and potentiate carbapenem antibiotics....
09/01/1992
 
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