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| Number | Title | Issue Date |
| 5536657 | Recombinant DNA encoding human receptor for interleukin-12 This invention relates to substantially pure Interleukin-12 receptor cDNAs and protein and uses therefore. The Interleukin-12 receptor is shown to be a member of the cytokine receptor superfamily and has a high homology to human gp130.... | 07/16/1996 |
| 5525481 | Enzymatic Reagents for ethanol assay containing diamino compounds An enzymatic assay assemblage for ethanol determination is provided. A diamino compound acts as a buffer and a trapping agent for a product of the enzymatic reaction. Long stability of the assay composition is achieved.... | 06/11/1996 |
| 5523400 | Cephalosporin antibiotics The present invention relates to compounds of the formula ##STR1## wherein R1 is an acyl group derived from a carboxylic acid, hydrogen, or an amino protecting group; R2 is hydrogen, hydroxy, lower alkyl-Qp -, cycloalkyl, ... | 06/04/1996 |
| 5510343 | Bicyclic and tricyclic ଲ-lactams There are described compounds of the formula ##STR1## in which R signifies lower alkoxycarbonyl, lower alkoxycarbonylamino, the acyl residue of an - or ଲ-amino acid or a residue of the general formula Q--X--Y-- ... | 04/23/1996 |
| 5494666 | ଲ-lactam compounds Compounds of the formula ##STR1## where Z, A, and R are as disclosed herein and pharmaceutically compatible, readily hydrolyzable esters and salts of these compounds are disclosed. The compounds have ଲ-lactamase inhibiting properties and are useful ... | 02/27/1996 |
| 5487817 | Process for tocopherols and sterols from natural sources A novel process for the recovery of tocopherols and sterols from natural, especially vegetable, sources. This process is especially a process for the separation of tocopherols and sterols from deodorizer sludges by distillation of these deodorizer sludges... | 01/30/1996 |
| 5486466 | Process for the preparation of DNA gyrase inhibitors Bicyclic derivatives of the general formula ##STR1## wherein X1 is --S-- or --SO--; X2 is --CO-- or --CS--; R1 is hydrogen, halogen or lower alkyl optionally substituted by halogen or lower alkoxy; R2 and R... | 01/23/1996 |
| 5464617 | ଲ-lactam compounds Compounds of the formula ##STR1## where Z, A, and R are as disclosed herein and pharmaceutically compatible, readily hydrolyzable esters and salts of these compounds are disclosed. The compounds have ଲ-lactamase inhibiting properties and are useful ... | 11/07/1995 |
| 5399741 | DNA gyrase inhibitors, process for their manufacture and pharmaceutical preparations containing same Compounds of the formula ##STR1## in which P is hydroxy and T is the group -X2 -CR7a R7b -CHR8 -OH or T is hydrogen and P is the group O-CHR8 -CR7a R7b -X2 -OH an... | 03/21/1995 |
| 5399585 | Carboxamides and sulfonamides compounds which have useful pharmaceutical utility Novel carboxamides and sulfonamides are described having of the formula R1 --A--(W)a --X--(CH2)b --(Y)c --B--Z--COOR(I), in which R1, A, W, X, Y, B, Z, R, a, b and c are as provided in the descriptio... | 03/21/1995 |
| 5336768 | Antibacterial cephalosporin compounds There are presented antibacterial cephalosporine having broad antimicrobial activity, having the formula ##STR1## wherein R is hydrogen or a carboxylic acid-protecting group: R1 represents a substituted piperazinyl group of formula ##... | 08/09/1994 |
| 5336683 | Antioxidants The invention is concerned with novel antioxidants, namely the [R] and, respectively, [S] compounds of the formula ##STR1## wherein R1 and R2 together represent the --S(O)-- group and R3 and R4 represent hy... | 08/09/1994 |
| 5329002 | Antibacterial cephalosporin compounds There are presented antibacterial cephalosporins having broad antimicrobial activity as well as intermediates for their formation, such compounds having the formula ##STR1## wherein R is hydrogen or a carboxylic acid-protecting group; R1 i... | 07/12/1994 |
| 5308549 | Stabilizers for thermo plastic materials Stabilizing mixtures for a plastic material are disclosed. The mixture is comprised of (a) about one part by weight of a tocopherol compound; and (b) from about 1.4 to about 5.0 parts by weight of a secondary antioxidant.... | 05/03/1994 |
| 5294609 | DNA gyrase inhibitors and pharmaceutical preparations therefor Bicyclic derivatives of the formula ##STR1## wherein X1, X2, R1, R2, R3, R4, R5, R6, R7a, R7b, and R8 are as defined in the speci... | 03/15/1994 |
| 5292648 | Microorganism of genus eupenicillium The compound of the formula ##STR1## and its tautomer are obtained from cultures of Eupenicillium sp. The compound has antifungal activity.... | 03/08/1994 |
| 5258373 | Anticoccidial compositions Compositions comprising a mixture of the antibiotic frenolicin B with a potentiated sulfonamide anticoccidial agent, useful for the treatment and prevention of coccidiosis in animals and methods of treating coccidiosis are disclosed.... | 11/02/1993 |
| 5256812 | Carboxamides and sulfonamides Novel carboxamides and sulfonamides are described having of the formula R1 --A--(W)a --X--(CH2)b --(Y)c --B--Z--COOR(I), in which R1, A, W, X, Y, B, Z, R, a, b and c are as provided in the descriptio... | 10/26/1993 |
| 5250517 | Renin inhibiting compounds Compounds which are amino acid derivatives and have the formula ##STR1## in which R1 is hydrogen or methyl, R2 is ethyl, propyl or imidazol-4-yl, R3 is isobutyl, cyclohexylmethyl or benzyl, and A is defined as herein ... | 10/05/1993 |
| 5229123 | Antifungal agents The compound of the formula ##STR1## and its tautomer are obtained from cultures of Eupenicillium sp. The compound has antifungal activity.... | 07/20/1993 |
| 5215993 | Anticoccidial compositions Compositions comprising a mixture of the antibiotic frenolicin B with halofuginone hydrobromide the anticoccidial agent, useful for the treatment and prevention of coccidiosis in animals and methods of treating coccidiosis are disclosed.... | 06/01/1993 |
| 5214046 | Substituted aminoalkoxybenzene anti-fungicidal compositions and use The compound of the formula ##STR1## wherein each of R1 and R2 individually is hydrogen, lower alkyl or lower alkenyl or together signify straight-chain alkylene with 2 to 4 carbon atoms, R3 is hydrogen, halogen or lo... | 05/25/1993 |
| 5200549 | Antipsoriatic agents The invention relates to compounds of the formula ##STR1## wherein R1 is hydrogen or methyl; ##STR2## wherein R2 is lower alkyl; R3 is phenyl, or phenyl substituted by 1 to 3 substituents selected from the group ... | 04/06/1993 |
| 5196438 | Amino acid derivatives Compounds having the formula ##STR1## wherein R is benzyloxycarbonyl or 2-quinolylcarbonyl, and their pharmaceutically acceptable acid addition salts inhibit proteases of viral origin and can be used as medicaments for the treatment of prophylaxis of... | 03/23/1993 |
| 5189157 | Antibacterial cephalosporin compounds There are presented antibacterial cephalosporins having broad antimicrobial activity as well as intermediates for their formation, such compounds having the formula ##STR1## wherein X is ##STR2## R is hydrogen or a carboxylic acid protectin... | 02/23/1993 |
| 5162523 | Cephalosporin antibacterial compounds Antibacterial compounds of the formula ##STR1## in which R1 is a cyclic or secondary acyclic amino group which independently has antibacterial activity; R2 is hydrogen, lower alkoxy, lower alkylthio or formamido; R3 is hyd... | 11/10/1992 |
| 5159077 | Penam antibacterial compounds Antibacterial compounds of the formula ##STR1## in which R1 is a cyclic or secondary acyclic amino group which independently has antibacterial activity: R2 is hydrogen, lower alkoxy, lower alkylthio or formamido; R3 is hyd... | 10/27/1992 |
| 5147871 | Anti-bacterial cephalosporin compounds There are presented anti-bacterial cephalosporins having broad antimicrobial activity of the formula ##STR1## wherein R1 is an antibiotically active quinolonyl; R2 is selected from the group consisting of hydrogen, lower alkoxy,... | 09/15/1992 |
| 5141854 | Enzymatic composition for ethanol assay An enzymatic assay composition for ethanol determination is provided. A compound of the formula H2 N--(CH2)n --CHR--CH2 --NH2 where R is H, CH3, or OH and N is 0-4 acts as a buffer and a trapping age... | 08/25/1992 |
| 5137920 | Method of treating fungal infections Compunds having the formula ##STR1## wherein each of R1 and R2 individually is hydrogen, lower alkyl, or lower alkenyl, R3 is hydrogen, halogen or lower alkyl, Q is alkylene with 2 to 11 carbon atoms and at least 2 ca... | 08/11/1992 |
| 5135924 | Therapeutic treatment of animals with oral administration of ormetoprim-potentiated sulfonamides Systemic bacterial infections caused by aerobic and anaerobic organisms in companion animals such as dogs can be treated effectively and conveniently by the oral administration on a once a day basis of an antibacterial combination of ormetoprim and a sulf... | 08/04/1992 |
| 5112967 | Process for synthesizing antibacterial cephalosporin compounds A process for synthesizing 3-acryloxymethyl antibacterialcephalosporin compounds of formula ##STR1## wherein R is hydrogen or a carboxylic acid protecting group; R1 is hydrogen or an acyl group; R2 is hydrogen or lower alkoxy; a... | 05/12/1992 |
| 5112856 | Therapeutic treatment of intestinal inflammation by administration of 3,4-dihydro-2H-1-benzopyran derivatives Inflammatory bowel disease and other leukotriene-mediated inflammation of the intestinal mucosa are treated therapeutically by the oral, rectal or parenteral administration of racemic-6-acetyl-7-[5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyloxy]-3,4-d ... | 05/12/1992 |
| 5110955 | Tocopherol synthesis: chromane cyclization and catalysis The invention relates to a process for the manufacture of vinylchromanes. This process is concerned with the manufacture of the compounds having the formula ##STR1## wherein Ro is hydrogen or a cleavable protecting group, and comprises ... | 05/05/1992 |
| 5106878 | Use of substituted aminoalkoxybenzene derivatives in the control or prevention of fungal infections The compound of the formula ##STR1## wherein each of R1 and R2 individually is hydrogen, lower alkyl or lower alkenyl or together signify straight-chain alkylene with 2 or 4 carbon atoms, R3 is hydrogen, halogen or lo... | 04/21/1992 |
| 5089503 | Temperature stable 5-fluorouracil compositions Temperature stable 5-fluorouracil compositions are disclosed. A solution of 5-fluorouracil and a base forms the composition. The pH of the composition is about 9.1 to about 9.3. The composition is less prone to precipitate at temperatures below 60° F.... | 02/18/1992 |
| 5084476 | Tetrahydronaphthalene and indane derivatives The compounds of the formula ##STR1## wherein X and Y are independently --CH2 -- or >C(CH3)2 ; Z is --CHR8 --, >CO, >CR8 OR7, --CHR8 --CHR8 --, --CHOR7... | 01/28/1992 |
| 5082589 | Liquid crystalline esters Compounds of the formula ##STR1## wherein m represents is the number of 0 to 1; A is a single convalent bond, --CH2 --CH2 --, --OCH2 --, --COO-- or --OOC--; rings B, C and D are 1,4-phenylene optionally substituted wi... | 01/21/1992 |
| 5081014 | Method of measuring a co-enzyme The method makes use of the action of the co-enzyme in the production of H2 O2 associated with the reaction of a hydroxylase with a decoupling agent in the presence of air or oxygen, the H2 O2 being subsequently... | 01/14/1992 |
| 5075447 | Ruthenium complexes useful as carriers for immunologically active materials The invention relates to a ruthenium complex having the formula Ru2+ L1 L2 L3 I wherein L1, L2 and L3 are the same or different are equal to a bi- or polycyclic li... | 12/24/1991 |
