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| Number | Title | Issue Date |
| 5543559 | Process for the enantioselective hydrogenation of ketosiophorone derivatives The present invention is concerned with a process for the manufacture of optically active compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy, phenyl, benzyl or --NR21, R1 signifies lower a... | 08/06/1996 |
| 5428071 | Prevention and treatment of premalignant epithelial lesions and malignant tumors of epithelial origin The compound 9-cis-retinoic acid, its pharmaceutically acceptable salts or its pharmaceutically acceptable esters can be used in the treatment of precancerous or premalignant epithelial lesions as well as in the treatment of malignant tumors of an epithel... | 06/27/1995 |
| 5352599 | Co-enzyme-independent L-sorbosone dehydrogenase of gluconobacter oxydans: isolation, characterization, and cloning and autologus expression of the gene A novel coenzyme independent L-sorbosone dehydrogenase originating from a microorganism belonging to the genus Gluconobacter oxydans which acts on L-sorbosone to produce 2-keto-L-gulonic acid. The enzyme has the following physico-chemical properties: a) optimu... | 10/04/1994 |
| 5310663 | Affinity peptides Fusion proteins and a process for their purification by means of metal chelate affinity chromatography on NTA resins are provided by this invention.... | 05/10/1994 |
| 5302738 | Chiral phosphines Novel, racemic and optically active phosphorus compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy or protected hydroxy, R1 signifies lower alkoxy, phenoxy, benzyloxy, chlorine or bromine, R2 stands f... | 04/12/1994 |
| 5298616 | Sulfated O-polysaccharide-trehaloses Sulphated O-Polysaccharide-trehaloses which can be used as medicaments, especially for the treatment of arteriosclerotic disorders.... | 03/29/1994 |
| 5284933 | Affinity peptides Fusion proteins and a process for their purification by means of metal chelate affinity chromatography on NTA resins are provided by this invention.... | 02/08/1994 |
| 5283346 | Dioxolanes Alcohols of the formula ##STR1## wherein R1 and R2 are each independently methyl or ethyl or together signify pentamethylene, formed by the enzymatic hydrolysis of a corresponding (RS) alkanoic acid ester are intermediates for V... | 02/01/1994 |
| 5274125 | Chirale phosphines Novel, racemic and optically active phosphorus compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy or a protected hydroxy group, R1 signifies a five membered heteroaromatic ring, R2 stands for lower a... | 12/28/1993 |
| 5232852 | Process for the production of dioxolanes Alcohols of the formula ##STR1## wherein R1 and R2 are each independently methyl or ethyl or together signify pentamethylene, formed by the enzymatic hydrolysis of a corresponding (RS) alkanoic acid ester are intermediates for V... | 08/03/1993 |
| 5229163 | Process for preparing a microtiter tray for immunometric determinations A microtiter plate containing a plurality of reaction wells for conducting immunogenic reactions the bottom wall of the reaction well has an inner surface which is substantially hydrophilic, and the side wall of the reaction well has an inner surface whic... | 07/20/1993 |
| 5210220 | Method for preparing derivatives of ascorbic acid The invention is concerned with a process for the manufacture of ascorbyl phosphates, namely of phosphates of the formula ##STR1## wherein Mk.sym. denotes a cation, k.sym. denotes the valency and m denotes the equivalents, wit... | 05/11/1993 |
| 5149829 | Method of preparing dry, concentrated salts of ascorbate 2-polyphosphate A method of preparing dried, concentrated ascorbate 2-polyphosphate salts is provided wherein a starting aqueous solution containing the desired 2-polyphosphate species (as well as contaminating inorganic phosphates) as sodium and potassium salts is subje... | 09/22/1992 |
| 5141748 | Implant drug delivery device A drug delivery device for subcutaneous implantation in animals having the ability to deliver drug at a controlled rate over a prolonged period of time, comprising a rod shaped polymeric inner matrix with an elongated body and two ends, said matrix having... | 08/25/1992 |
| 5096695 | Radioiodine benzodiazepines as brain imaging agents Radioiodine 5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine derivatives and their use as brain imaging agents.... | 03/17/1992 |
| 5085993 | Coenzyme-independent L-sorbosone dehydrogenase from Pseudomonas putida A coenzyme-independent L-sorbosone dehydrogenase has been prepared from a microorganism belong to the genus Pseudomonas, which acts on L-sorbosone to produce 2-keto-L-gulonic acid. The enzyme is membrane bound and has a molecular weight of about 47,000 kD... | 02/04/1992 |
| 4925784 | Expression and purification of an HTLV-III gag/env gene protein Methods and compositions are provided for the cloning and expression of plasmids bearing genes encoding a novel protein derived from HTLV-III. This protein, which is called the gag/env protein and which contains antigenic determinants from both the core a... | 05/15/1990 |
| 4921699 | Polypeptides having interferon activity A polypeptide having interferon activity which has an amino acid sequence corresponding to an amino acid sequence of an interferon selected from rIFN-, hybrid rIFN-, rIFN-ଲ and rIFN-γ interferons in which at least one cysteine residue... | 05/01/1990 |
