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| Number | Title | Issue Date |
| D599499 | Cosmetic skin removal device | 09/01/2009 |
| 7566348 | Method for coloring hair A two step high lift method for oxidatively coloring hair comprising a first step of applying to the hair a lifting mixture comprised of an aqueous oxidizing agent composition and a lifting composition to the hair for a period of time sufficient to lift the hair, fo... | 07/28/2009 |
| 7494514 | Method and compositions for coloring hair An oxidative dye composition comprising one or more oxidative dyes, at least one glyceryl ester, and at least one surfactant, a method for coloring hair, and a method for coloring First Grays and hair that has been chemically processed with a mild, easy to use, hair... | 02/24/2009 |
| D572604 | Combined mascara brush and package | 07/08/2008 |
| D566892 | Cosmetic applicator | 04/15/2008 |
| D560854 | Skin smoothing implement | 01/29/2008 |
| D552485 | Tube with cap | 10/09/2007 |
| 7278431 | Device for smoothing keratinous surfaces A skin grooming device comprising a planar surface for removable attachment to a stationary surface, having affixed thereto an undulating abrasive block for use in abrading rough, dead, or dry skin from keratinous surfaces and a method for grooming skin using the de... | 10/09/2007 |
| D546697 | Bottle | 07/17/2007 |
| D545497 | Nail care implement and case | 06/26/2007 |
| D545496 | Implement for skin and nail care | 06/26/2007 |
| 7078572 | Process for the synthesis of intermediates useful for the synthesis of tubulin inhibitors The invention is a process for the preparation of compounds of the Formula I: where R1, R2, R3, R4 and R5 are defined in the specification, which are interme... | 07/18/2006 |
| 6995001 | Processing for preparing monoprotected diols from symmetric diols This invention provides a two-step enzymatic process for the synthesis of monoprotected diols from symmetric diols. ... | 02/07/2006 |
| 6951955 | Process for the synthesis of intermediates useful for the synthesis of tubulin inhibitors The invention is a process for the preparation of compounds of the Formula I: where R1, R2, R3, R4 and R5 are defined in the specification, which are intermediates... | 10/04/2005 |
| 6933388 | Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolones There is provided a process for the preparation of 3-cyano-6-alkoxy-7-nitro-4-quinolone intermediates useful for the preparation of protein tyrosine kinase (PTK) inhibitors which are useful in the treatment of cancer of the formula: | 08/23/2005 |
| 6821988 | 3-cyanoquinolines as inhibitors of EGF-R and HER2 kinases This invention provides compounds of Formula (I), represented by the structure wherein G1, G2, G3, G4, Z, X and n are defined herein, or a pharmaceutically acceptable salt th... | 11/23/2004 |
| 6780996 | Process for the preparation of 7-substituted-3 quinolinecarbonitriles There is provided a process for the preparation of 7-substituted-3-quinolinecarbonitriles and intermediates useful in a process to prepare 7-substituted-3-quinolinecarbonitriles and pharmaceutically acceptable salts is described. Where 7-fluoro-4-oxo-1,4-dihydro-3-q... | 08/24/2004 |
| 6689772 | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors This invention provides compounds of Formula (I), having the structure ##STR1## where T, Z, X, A, R1, R2a, R2b, R2c, R3, R4, and n are defined herein, or a pharmaceutically acceptable salt there... | 02/10/2004 |
| 6608048 | Tricyclic protein kinase inhibitors This invention provides compounds of Formula (I), ##STR1## where A", Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.... | 08/19/2003 |
| 6555561 | Diaminopyridine-containing thiourea inhibitors of herpes viruses This invention provides compounds of formula I having the structure ##STR1## Wherein substitutions at X, G, R1, R2, R3, R4, R5 are set forth in the specification.... | 04/29/2003 |
| 6548524 | Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors This invention provides, non-peptide inhibitors of matrix metalloproteinases (e.g. gelatinases, stromelysins and collagenases) and TNF- converting enzyme (TACE. tumor necrosis factor- converting enzyme) which arc useful for the treatment of ... | 04/15/2003 |
| 6548496 | Substituted 3-cyano-[1.7], [1.5], and [1.8] naphthyridine inhibitors of tyrosine kinases This invention provides compounds of formula I having the structure ##STR1## Wherein substitutions at A", Z, n, and X are set forth in the specification.... | 04/15/2003 |
| 6534491 | Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors This invention provides, non-peptide inhibitors of matrix metalloproteinases (e.g. gelatinases, stroinelysins and collagenases) and TNF- converting enzyme (TACE, tumor necrosis factor-댜onverting enzyme) which are useful for the treatment of ... | 03/18/2003 |
| 6498167 | Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and tace inhibitors This invention provides low molecular weight, non-peptide inhibitors of matrix metalloproteinases and TNF- converting enzyme (TACE, tumor necrosis factor- converting enzyme) of formula (B) as shown herein or a pharmaceutically acceptable sal... | 12/24/2002 |
| 6462073 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors Matrix metalloproteinases (MMPs) are a group of enzymes that have been implicated in the pathological destruction of connective tissue and basement membranes. These zinc containing endopeptidases consist of several subsets of enzymes including collagenase... | 10/08/2002 |
| 6462055 | Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group Compounds having the formula: ##STR1## wherein R1 -R5 are independently selected from hydrogen, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkynyl of 2 to 6 carbon atoms, perhaloalkyl of 1 to 6 carbon atoms, cycloa... | 10/08/2002 |
| 6444704 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors Matrix metalloproteinases (MMPs) are a group of enzymes that have been implicated in the pathological destruction of connective tissue and basement membranes. These zinc containing endopeptidases consist of several subsets of enzymes including collagenase... | 09/03/2002 |
| 6441023 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors Matrix metalloproteinases (MMPs) are a group of enzymes that have been implicated in the pathological destruction of connective tissue and basement membranes. These zinc containing endopeptidases consist of several subsets of enzymes including collagenase... | 08/27/2002 |
| 6426355 | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group Compounds having the formula: ##STR1## wherein R1 -R5, X and G are described herein and which are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Bar... | 07/30/2002 |
