Did You Know...
...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7230075 | Coccidiosis poultry vaccine This invention relates to novel Eimeria proteins with immunogenic properties as well as to DNA sequences encoding these proteins. These proteins can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding thes... | 06/12/2007 |
| 6218365 | Serine protease inhibitors The invention relates to a cornound having formula (I), wherein A, B, X, Y and r are as defined in the description, or a prodrug thereof or a pharnnaceutically acceptable salt thereof. The compounds of the invention have anticoagulant activity and can be ... | 04/17/2001 |
| 6177420 | 20-aralkyl-5-pregnane derivatives The invention relates to 20-aralkyl-5-pregnane derivative having general formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 is (H,OR), (H,OSO3 H) or NOR; R is H, (C1-6)alkyl or (C1-6)a... | 01/23/2001 |
| 6150548 | Linkers The invention relates to a compound having the formula I ##STR1## wherein R1 is hydroxy, (1-6C)alkoxy or NR4 R5, R4 and R5 being independently hydrogen, (1-6C)alkyl, (3-7C)cycloalkyl, (2-6C)alken... | 11/21/2000 |
| 6150353 | Therapeutic combinations of mirtazapine and antipsychotic agents, for the treatment or prophylaxis of psychotic disorders This application relates to a combination of the antidepressant mirtazapine and an antipsychotic agent such as haloperidol for the treatment of psychotic disorders.... | 11/21/2000 |
| 6143865 | Epstein-Barr virus peptides and antibodies against these peptides The invention relates to peptides or fragments thereof which are immunochemically reactive with Epstein-Barr Virus (EBV) antibodies. New antibodies directed to said peptides or fragments thereof are also part of the invention.... | 11/07/2000 |
| 6129920 | Inactivated infectious bursal disease vaccine The present invention is concerned with Infectious bursitis virus (IBDV) vaccines containing IBDV antigen material which is derived from a mammalian cell line infected with IBDV.... | 10/10/2000 |
| 6127425 | Oral liquid medicine solution Found is a pharmaceutical preparation which provides Tamoxifen Citrate in a liquid dosage form, viz. as an oral solution. The finding is based on a solvent comprising the following components: (a) of from 10% to 20% by weight of ethanol, (b) of from 10% t... | 10/03/2000 |
| 6114324 | Oral liquid antidepressant solution For the oral administration of the anti-depressant mirtazapine an aqueous solution or suspension is found which is preferably stabilized by methionine, is thickened, and which has a pH of from 2.5 to 3. By the formulation according to the invention, an un... | 09/05/2000 |
| 6114131 | Methods for the detection of antibodies to ornithobacterium rhinotracheale The present invention relates to a novel bacterial respiratory poultry disease and the identification of the causative agent. A vaccine derived from this agent was effective in preventing the disease in chickens challenged with the virulent field strains.... | 09/05/2000 |
| 6106836 | Container with freeze-dried vaccine components The present invention relates to a vaccine container that contains one or more freeze-dried vaccine components. The vaccine component or components are present in two or more freeze-dried bodies, at least one of which is a lyosphere. Furthermore, the inve... | 08/22/2000 |
| 6100241 | Coccidiosis poultry vaccine This invention relates to Eimeria proteins with immunogenic properties as well as to DNA sequences encoding these proteins. These proteins can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding these ... | 08/08/2000 |
| 6086892 | Poultry vaccine This invention relates to a novel infectious bronchitis virus (IBV) serotype and to attenuated IBV strains derived therefrom, and also to live or inactivated vaccines made using such IB virus. This invention also relates to a method for protecting poultry... | 07/11/2000 |
| 6080773 | Benzylamine derivatives which are useful in treating psychiatric disorders The present invention relates to certain novel benzylamine derivatives, to processes for their preparation, to pharmaceutical formulations containing them and to their use in medical therapy, particularly in the treatment of depression.... | 06/27/2000 |
| 6054145 | Making dosage units using low shear granulation Disclosed is a process for the preparation of pharmaceutical dosage units containing as an active substance of from 0.005 to 1.0% by weight of micronised Org 30659, comprising (a) a mixing step comprising bringing into association the active substance and... | 04/25/2000 |
| 6046023 | Microbial 11-hydroxylation of steroids The invention relates to a microbial method of in vitro transformation of a steroid into its corresponding 11-hydroxy analogue using oxygen and a microorganism selected from the Aspergillus ochraceus, Aspergillus niger, Rhizopus stolonifer, Rhizopu... | 04/04/2000 |
| 6040301 | Oral liquid antidepressant solution For the oral administration of the anti-depressant mirtazapine an aqueous solution or suspension is found which is preferably stabilized by methionine, is thickened, and which has a pH of from 2.5 to 3. By the formulation according to the invention, an un... | 03/21/2000 |
| 6034067 | Serine protease inhibitors The invention relates to a compound having formula (I), wherein A, B, X, N, Z and Q are defined as described in the description. The compounds of the invention have anticoagulant activity and can be used in treating or preventing thrombin-related diseases... | 03/07/2000 |
| 6033844 | Porcine reproduction respiratory syndrome diagnostic The present invention is directed to the identification of the causative agent of Porcine Reproductive Respiratory Syndrome virus and vaccines derived therefrom. The present invention is also directed to viral antigens produced by tissue culture cells inf... | 03/07/2000 |
| 6013266 | Live attenuated bacteria of the species Actinobacillus pleuropneumoniae The present invention relates to live attenuated bacteria of the genus Actinobacillus pleuropneumoniae that have a mutation in an apxIV gene such that no functional ApxIV toxin can be produced. The invention also relates to methods for the production of s... | 01/11/2000 |
| 6011025 | 11-(substituted phenyl)-estra-4,9-diene derivatives The invention relates to a 11-(substituted phenyl)-estra-4,9-diene derivative of formula I ##STR1## wherein A, X, R1 and R2 are as defined by the specification. The compounds of the invention have anti-glucocorticoid activity an... | 01/04/2000 |
| 6008327 | Peptides and nucleic acid sequences related to the Epstein Barr virus The present invention relates to peptides immunochemically reactive with antibodies to the Epstein-Barr virus (EBV), comprising at least part of the VCA-p18 or VCA-p40 protein, encoded within the EBV open reading frames BFRF3 and BdRF1 respectively, or a ... | 12/28/1999 |
| 6005124 | Method for the preparation of steroid derivative ketal The invention relates to a method for the preparation of a steroid derivative ketal of formula I: ##STR1## characterized in that a compound of formula II: ##STR2## is treated with an alcohol in the presence of an orthoester, wherein R1... | 12/21/1999 |
| 6001363 | Coccidiosis poultry vaccine This invention relates to a novel Eimeria protein with immunogenic properties as well as to DNA sequences encoding these proteins. This protein can be administered to poultry thereby protecting the birds against coccidiosis. In addition the DNA encoding t... | 12/14/1999 |
| 5998639 | Sulfatation of estrogen mixtures The invention relates to a method for the preparation of a mixture of sulfated estrogens containing delta(8,9)-dehydro estrone [delta(8,9)DHE] or derivatives thereof.... | 12/07/1999 |
| 5994080 | Method of diagnosing an increased risk of thrombus associated disease by detecting a certain t-PA polymorphism Blood clot formation is the key event in myocardial infarction. Besides increased coagulation, failure in blood clot lysis can induce undesired coronary thrombosis. Plasmin is essential for degradation of fibrin clots. Tissue-type plasminogen activator (t... | 11/30/1999 |
| 5977099 | Pharmaceutical composition comprising mirtazapine and one or more selective serotonin reuptake inhibitors The invention relates to a pharmaceutical composition comprising mirtazapine, a selective serotonin reuptake inhibitor (SSRI) and pharmaceutically acceptable auxiliaries. In particular the SSRI is selected from fluoxetine, fluvoxamine, citalopram, cericla... | 11/02/1999 |
| 5965134 | Immunogenic composition against Classical Swine Fever Virus (CSFV) This application is concerned with immunogenic polypeptides of pestiviruses, specifically Classical Swine Fever Virus (CVFV), specifically the nonstructural protein p10, more specifically T-cell epitopes from this protein and nucleic acid molecules encodi... | 10/12/1999 |
| 5965106 | In vivo binding pair pretargeting A method for in-vivo targeting a functional moiety in a patient by administering a targeting moiety coupled to an affinity component, wherein the targeting moiety has affinity for binding sites in a target area, and administering a binding partner to the ... | 10/12/1999 |
| 5965353 | Epstein-Barr virus peptides and antibodies against these peptides The invention relates to a peptide or fragment thereof which is immunochemically reactive with Epstein-Barr Virus (EBV) antibodies. A new monoclonal antibody directed to said peptide or fragment thereof is also part of the invention. The invention also re... | 10/12/1999 |
| 5955622 | Method for the preparation of steroid derivative ketal The invention relates to a method for the preparation of a compound of formula II: ##STR1## wherein a compound of formula V: ##STR2## is condensed with a compound of the formula CH3 -C(OR4 O)-(CH2)3 | 09/21/1999 |
| 5939073 | Fish pancreatic disease virus There is described a novel virus which is the causative agent of fish pancreatic disease, which is a serious disease affecting Atlantic salmon. A method of isolating the virus through co-cultivation of infected tissues following by passage is described an... | 08/17/1999 |
| 5935582 | Hog cholera virus vaccine and diagnostic The present invention is concerned with a hog cholera virus vaccine comprising a polypeptide characteristic of hog cholera virus. Vector vaccines capable to express a nucleic acid sequence encoding such a polypeptide also from part of the present inventio... | 08/10/1999 |
| 5929028 | Liquid gonadotropin containing formulations The invention concerns a liquid gonadotropin-containing formulation characterised in that the formulation comprises a gonadotropin and stabilising amounts of a polycarboxylic acid or a salt thereof and of a thioether compound. The particular proteins (e.g... | 07/27/1999 |
| 5925361 | Ornithobacterium rhinotracheale vaccines The present invention relates to a novel bacterial respiratory poultry disease and the identification of the causative agent. A vaccine derived from this agent was effective in preventing the disease in chickens challenged with the virulent field strains.... | 07/20/1999 |
| 5925518 | Nucleic acid primers for amplification of a mycobacteria RNA template Disclosed is a pair of primers to amplify a homologous region of the 16S rRNA of Mycobacteria. The primer pair performs better than a number of other primer pairs in a transcription-based amplification system. The amplified RNA can be detected with known ... | 07/20/1999 |
| 5925347 | Viral vector vaccines comprising nucleic acids encoding eimeria proteins for poultry vaccination against coccidiosis The invention is concerned with novel Eimeria proteins with immunogenic properties as well as with DNA sequences encoding these proteins. These proteins can be administered to chickens thereby protecting the chickens against coccidiosis. In addition the D... | 07/20/1999 |
| 5916593 | Process of making dosage units by wet granulation The invention relates to a process of making pharmaceutical dosage units comprising at least desogestrel or Org 30659 (17-17-hydroxy-11-methylene-19-norpregna-4,15-dien-20-yn-3-one), present in an amount of about 0.005 to 1.0 percent by weight of e... | 06/29/1999 |
| 5916888 | Imidazo1,5A!pyridine derived serine protease inhibitors The invention relates to an imidazole1,5a!pyridine derived serine protease inhibitor comprising a unit having general formula (I) ##STR1## wherein R1 is hydrogen, lower alkyl or an acyl group; R2 is hydrogen or lower alkyl; R | 06/29/1999 |
| 5914260 | Fish pancreatic disease virus There is described a novel virus which is the causative agent of fish pancreatic disease, which is a serious disease affecting Atlantic salmon. A method of isolating the virus through co-cultivation of infected tissues following by passage is described an... | 06/22/1999 |
