Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 6395473 | Adenoviral based promoter assay Adenoviral vectors are used to transfer a promoter/reporter gene construct to mammalian cell cultures. The promoter/reporter gene construct is used to determine if a candidate inducing agent has promoter-inducing activity; or can be used to determine if a... | 05/28/2002 |
| 6358744 | Stabilized human papillomavirus formulations Human papillomavirus (HPV) antigen formulations are disclosed which prevent protein aggregation and show prolonged stability as aqueous solutions. These formulations comprise a salt (such as sodium chloride) and a non-ionic surfactant (Polysorbate 80 such... | 03/19/2002 |
| 6350595 | Synthesis of polynucleotides having random sequences Subject of this invention is a process for the chemical synthesis of polynucleotides having totally or partially random sequences, based on the utilization, as synthesis monomer units for the random sequence part, or presynthesized mononucleotides and din... | 02/26/2002 |
| 6290965 | DNA encoding human papillomavirus type 6A The present invention is directed to DNA molecules encoding purified human papillomavirus type 6a and compounds derived therefrom.... | 09/18/2001 |
| 6280740 | Formulations of recombinant papillomavirus vaccines Vaccine formulations comprising recombinant early (E) and late (L) proteins of papillomavirus and oxidized mannan as well as methods of making and using the formulations are provided.... | 08/28/2001 |
| 6251678 | Human papillomavirus vaccine formulations New human papilloma virus (HPV) vaccine formulations exhibit enhanced long-term stability. Formulation components can include: virus-like particles (VLPs) absorbed onto aluminum, a salt, non-ionic surfactant, and a buffer. Additional formulations also con... | 06/26/2001 |
| 6159729 | Synthetic HPV6/11 hybrid L1 DNA encoding human papillomavirus type 11 L1 protein The present invention is directed to a synthetic DNA molecule encoding purified human papillomavirus type 11 L1 protein and derivatives thereof.... | 12/12/2000 |
| 5952216 | Synthetic HPV 16 virus-like particles A series of synthetic virus-like particles useful in the characterization of human papillomavirus type 16 (HPV16) infection and assays employing the synthetic particles are provided.... | 09/14/1999 |
| 5922588 | Synthetic HPV16 virus-like particles The invention is a series of synthetic virus-like particles useful in the characterization of human papillomavirus infection and assays employing the synthetic virus-like particles.... | 07/13/1999 |
| 5895754 | Nucleic acids encoding a truncated mouse ଲ integrin subunit The full-length mouse 댣 integrin has been cloned and sequenced. A new form of 댣 integrin (댣 trunc ) has also been cloned and sequenced.... | 04/20/1999 |
| 5888516 | Recombinant papillomavirus vaccines Recombinant expression vectors encoding the L1 and L2 proteins of papillomavirus, methods of making and using the recombinant proteins and purified virus-like particles comprised of the recombinant proteins are provided.... | 03/30/1999 |
| 5866553 | Polynucleotide vaccine for papillomavirus DNA constructs encoding papilloma virus gene products, capable of being expressed upon direct introduction into animal tissues, are novel prophylactic pharmaceuticals which can provide immune protection against infection by papilloma virus.... | 02/02/1999 |
| 5856186 | Method for producing a highly enriched population of osteoclast cells Methods of obtaining enriched populations of osteoclast precursor cells which can be released from tissue culture dishes and used for biochemical studies are described. Osteoblastic cells and bone marrow cells are co-cultured. Next a v &... | 01/05/1999 |
| 5821087 | Production of recombinant human papillomavirus type II protein utilizing papillomavirus 6/11 hybrid DNA The present invention is directed to a recombinant human papillomavirus type 11 L1 protein encoded by a synthetic DNA molecule and methods of making and using the protein.... | 10/13/1998 |
| 5820870 | Recombinant human papillomavirus type 18 vaccine The present invention is directed to vaccines for human papillomavirus type 18 and derivatives thereof.... | 10/13/1998 |
| 5795754 | Synthetic HPV11 virus-like particles The present invention is a series of synthetic virus-like particles useful in the characterization of human papillomavirus infection and assays employing the synthetic virus-like particles.... | 08/18/1998 |
| 5738853 | Synthetic HPV11 virus-like particles The present invention is a series of synthetic virus-like particles useful in the characterization of human papillomavirus infection and assays employing the synthetic virus-like particles. The synthetic virus-like particles are generated from constructs ... | 04/14/1998 |
| 5728557 | Method of making herpes simplex type 1 mutants and mutants so produced A method for introducing a mutation into a desired site in Herpes Simplex Virus Type 1 uses a set of starting vectors, where each starting vector has a fragment of the substantially complete HSV-1 genome and also DNA which overlaps with a sequential genom... | 03/17/1998 |
| 5721120 | Method of disrupting cultured cells using an impinging jet device A novel method of disrupting cells which do not have a cell wall comprises passing suspended cells through a low pressure impinging jet device. This method disrupts the cells, but does not harm the cell products which are liberated.... | 02/24/1998 |
| 5719058 | Method for producing a highly enriched population of osteoclast cells Methods of obtaining enriched populations of osteoclast precursor cells which can be released from tissue culture dishes and used for biochemical studies are described. Osteoblastic cells and bone marrow cells are co-cultured. Next a v &... | 02/17/1998 |
| 5660989 | DNA polymerase extension assay for influenza virus endonuclease An assay for the influenza virus endonuclease has been developed which involves DNA polymerase-catalyzed extension of the viral endonuclease cleavage product using labeled nucleotides and a DNA template containing a 3' region complementary to the product ... | 08/26/1997 |
| 5623057 | Pneumococcal polysaccharide conjugate vaccine A novel conjugate vaccine comprising partially hydrolyzed, highly purified, capsular polysaccharide (Ps) from Streptococcus pneumoniae bacteria (pneumococci, Pn) linked to an immunogenic carrier protein, is produced by a new process. The conjugate is usef... | 04/22/1997 |
| 5618685 | Activation of herpes simplex virus protease by kosmotropes Native Herpes Simplex Virus type 1 (HSV type 1) protease has a rather low activity. It has been found however, that the presence of a kosmotropic anion can increase the activity of the protease over 10-fold. This has many advantages, as now assays for pro... | 04/08/1997 |
| 5606030 | Coconjugates of OMPC, HIV related peptides and anionic moieties A novel coconjugate comprising an immunogenic protein or protein complex having a first set of covalent linkages to low molecular weight moieties, --a--, which have an anionic or polyanionic character at physiological pH, and a second set of co... | 02/25/1997 |
| 5494808 | Defined medium OMPC fermentation process A new fermentation process for the culture of Neisseria meningitidis incorporates a wholly synthetic medium and event based processing decisions. This process is capable of generating cells at production scale for the extraction and purification of outer ... | 02/27/1996 |
| 5486470 | Purified herpes simplex virus protease and methods of purification A method of purifying proteases from the Herpes Simplex Virus 1 and 2 is taught. A precursor protease is cloned in a host cell and then separated from the cell culture using cation exchange chromatography. The resulting protease is subjected to autoproces... | 01/23/1996 |
