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Attorney: Genieser; Lars H.


Number of patents: 24
Last date: May 22, 2012

NumberTitleIssue Date
8183274Treatment of hyperproliferative disorders with diarylhydantoin compounds
The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer. ...
05/22/2012
8110594Diarylthiohydantoin compounds
The present invention relates to diarylthiohydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer. ...
02/07/2012
8057682Green synthesis of nanometals using plant extracts and use thereof
The present invention relates to methods of making and using and compositions of metal nanoparticles formed by green chemistry synthetic techniques. For example, the present invention relates to metal nanoparticles formed with solutions of plant extracts and use of ...
11/15/2011
8034548Methods and materials for assessing prostate cancer therapies
Using microarray-based profiling of isogenic prostate cancer xenograft models, we found that a modest (2-5 fold) increase in androgen receptor (AR) mRNA was the only expression change consistently associated with developing resistance to antiandrogen therapy. Increa...
10/11/2011
7998923Bioactivation of particles
Particles are bioactivated by attaching bioactivation peptides to the particle surface. The bioactivation peptides are peptide-based compounds that impart one or more biologically important functions to the particles. Each bioactivation peptide includes a molecular ...
08/16/2011
7976241Soil remediation method and composition
A method for in-situ reduction of contaminants in soil. ...
07/12/2011
7964247Process and apparatus for the manufacture of a sputtering target
A process for the manufacture of sputtering target comprises the steps of i) providing a substrate; ii) plasma melting of a material selected to form the sputtering target, yielding droplets of molten material; and iii) deposition of the droplets onto the substrate,...
06/21/2011
7963720Polymer coated nanoparticle activation of oxidants for remediation and methods of use thereof
Methods of decreasing the amount of one or more contaminants in contaminated soil comprise introducing polymer-coated nanoparticles into the contaminated soil, optionally with other reagents. The polymer-coated nanoparticles exhibit an enhanced ability to migrate th...
06/21/2011
7943396Peptide-coated nanoparticles with graded shell compositions
A peptide-coated nanoparticle that includes a nanocrystal core surrounded by a graded shell that is composed of at least two different semiconductor molecules. At least one peptide is attached to the surface of the graded shell to render the nanoparticle biocompatib...
05/17/2011
7910048Apparatus for plasma synthesis of rhenium nano and micro powders
The process for the synthesis of rhenium powders comprises the injection of ammonium perrhenate powder through a carrier gas in a plasma torch of a plasma reactor operated using a mixture including hydrogen as the plasma gas, yielding metallic rhenium under the foll...
03/22/2011
7718684Methods and materials for assessing prostate cancer therapies and compounds
A modest (2-5 fold) increase in androgen receptor (AR) mRNA is the only expression change consistently associated with developing resistance to antiandrogen therapy. Increased levels of AR confer resistance to anti-androgens by amplifying signal output from low leve...
05/18/2010
7709517Diarylhydantoin compounds
The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer. ...
05/04/2010
7687628Method of preparing 4-amino-1-imidazo(4,5-)quinolines and acid addition salts thereof
The present invention provides a method of preparing a 4-(arylmethyl)amino-1H-imidazo(4,5-c)quinoline of formula (4) by reacting an arylmethylamine of formula (3) with a 4-chloro-1H-imidazo(4,5-c)quinoline of formula (2). The present invention further provides a met...
03/30/2010
7590942System, method and computer program product for documenting and managing execution of procedures in a graphical interface environment
A system, method and computer program product for describing a process visually, converting the visual description to an intermediate format, and directing the process. ...
09/15/2009
7494527Process for plasma synthesis of rhenium nano and micro powders, and for coatings and near net shape deposits thereof and apparatus therefor
The process for the synthesis of rhenium powders comprises the injection of ammonium perrhenate powder through a carrier gas in a plasma torch of a plasma reactor operated using a mixture including hydrogen as the plasma gas, yielding metallic rhenium under the foll...
02/24/2009
7371413Antioxidant and anti-inflammatory activity of compounds and preparations from African nutmeg seeds
The present invention provides methods for reducing the production of nitric oxide, inducible nitric oxide synthase protein and mRNA, and cyclooxygenase-2 protein and mRNA in cells both in vivo and in vitro via the administration of extracts and compounds derived fr...
05/13/2008
7363922Flat chisel
The invention relates to a flat chisel, in particular an insertion chisel for power-driven drill and chisel hammers for working stone, having a chisel head which has a main tip disposed transversely to a chisel longitudinal axis, a front and rear striking surface, a...
04/29/2008
7355697Flow-through, thermal-expansion-compensated cell for light spectroscopy
Optical cells are non-actively compensated to ensure that a sample gap of a sample space remains nearly constant upon a change in temperature. Fluids can be flowed through the sample space of the optical cells. ...
04/08/2008
7329608Method of processing a substrate
The invention is embodied in a plasma flow device or reactor having a housing that contains conductive electrodes with openings to allow gas to flow through or around them, where one or more of the electrodes are powered by an RF source and one or more are grounded,...
02/12/2008
7288660Process for preparing ondansetron hydrochloride dihydrate having a defined particle size
The invention provides a process for preparing ondansetron hydrochloride dihydrate particles in which at least about 70% of the particles have a particle size of less than 250 μm, comprising the steps of: (a) preparing a solution ...
10/30/2007
7199592Method and apparatus for applying microwaves to measure the moisture content of material
Apparatus for ascertaining the mass and/or the moisture content of successive increments of a running rod containing tobacco and/or filter material for tobacco smoke has a resonator housing with a cylindrical internal chamber which is disposed between an inlet and a...
04/03/2007
D527266Bottle dome
08/29/2006
D494473Bottle dome
08/17/2004
6756379Non-sedating barbiturate compounds as neuroprotective agents
Methods of providing neuroprotection are disclosed comprising administering a non-sedative barbiturate compound in an amount sufficient to achieve neuroprotection in a mammalian subject. Preferred compounds are in the family of diphenylbarbituric acid and analogs. P...
06/29/2004
 
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