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| Number | Title | Issue Date |
| 7192740 | Recombinant viral nucleic acids The present invention relates to a recombinant viral nucleic acid selected from a (+) sense, single stranded RNA virus possessing a native subgenomic promoter encoding for a first viral subgenomic promoter, a nucleic acid sequence that codes for a viral coat protein... | 03/20/2007 |
| 7179638 | Microarrays and their manufacture by slicing Microarrays are prepared by using a separate fiber for each compound being used in the microarray. The fibers are bundled and sectioned to form a thin microarray that may be glued to a backing. ... | 02/20/2007 |
| 7133544 | Reference database Data acquisition and cataloging are used to classify polypeptides into a reference index or database. The database can be used to identify previously unidentified samples. New polypeptides are characterized and added to the database. ... | 11/07/2006 |
| 7130459 | Reference database Data acquisition and cataloging are used to classify polypeptides into a reference index or database. The database can be used to identify previously unidentified samples. New polypeptides are characterized and added to the database. ... | 10/31/2006 |
| 7084256 | Self antigen vaccines for treating B cell lymphomas and other cancers A polypeptide self-antigen useful in a tumor-specific vaccine mimics one or more epitopes of an antigen uniquely expressed by cells of the tumor. The polypeptide is preferably produced in a plant that has been transformed or transfected with nucleic acid encoding th... | 08/01/2006 |
| 7070739 | Detection and characterization of microorganisms A method for separating microorganisms, especially infectious agents, from a mixture by two dimensional centrifugation on the basis of sedimentation rate and isopycnic banding density, for sedimenting such microorganisms through zones of immobilized reagents to whic... | 07/04/2006 |
| 7056740 | Mismatch endonucleases and methods of use We describe here restriction endonucleases and their uses. Restriction endonucleases are useful in finding single nucleotide polymorphisms. They are also useful in an in vitro method of redistributing sequence variations between non-identical polynucleotide sequence... | 06/06/2006 |
| 7049134 | Rolling circle replicon expression vector A rolling circle DNA replicon which replicates in a host eukaryotic cell is disclosed which has a truncated replication cycle. The rolling circle DNA replicon comprises the following elements present on the same DNA molecule. It contains a Rep gene open reading fram... | 05/23/2006 |
| 7033835 | Production of peptides in plants as viral coat protein fusions The present invention relates to foreign peptide sequences fused to recombinant plant viral structural proteins and a method of their production. Fusion proteins are economically synthesized in plants at high levels by biologically contained tobamoviruses. The fusio... | 04/25/2006 |
| 7034128 | Method for recovering proteins from the interstitial fluid of plant tissues A method for extracting proteins from the intercellular space of plants is provided. The method is applicable to the large scale isolation of many active proteins of interest synthesized by plant cells. The method may be used commercially to recover recombinantly pr... | 04/25/2006 |
| 6980674 | Reference database Data acquisition and cataloging are used to classify polypeptides into a reference index or database. The database can be used to identify previously unidentified samples. New polypeptides are characterized and added to the database. ... | 12/27/2005 |
| 6939453 | Electrophoresis process using ionic liquids Highly hydrophobic compounds and hydrophobic proteins are solubilized in a non-aqueous solvent containing an electrolyte for electrophoretic separation. The non-aqueous solvent is an ionic liquid or a mixture of an organic solvent containing an ionic liquid in an am... | 09/06/2005 |
| 6932895 | Automated electrophoresis gel manipulation apparatus An automated, computer controlled assembly is provided for continuously processing a large number of electrophoresis gels. The assembly includes a loading assembly for loading a gel onto a carrier, a gel staining assembly and a scanning and cutting assembly. The sta... | 08/23/2005 |
| 6933109 | Rapid particle detection Methods and reagents for rapid purification and/or identification of particles in a liquid sample are described. The technique uses centrifugation to concentrate particles against a slanted surface having an agent specifically binding to the particles. This method i... | 08/23/2005 |
| 6890748 | Production of lysosomal enzymes in plants by transient expression The invention relates to α-galactosidase truncated at the carboxy terminus and the production of enzymatically active recombinant human and animal lysosomal enzymes involving construction and expression of recombinant expression constructs comprising coding sequenc... | 05/10/2005 |
| 6887701 | Microarrays and their manufacture The microarrays of the present invention are prepared by using a separate fiber for each compound being used in the microarray. The fibers are bundled and sectioned to form a thin microarray that is glued to a backing. ... | 05/03/2005 |
| 6887696 | Production of lysosomal enzymes in plants by transient expression The invention relates to α-galactosidase truncated at the carboxy terminus and the production of enzymatically active recombinant human and animal lysosomal enzymes involving construction and expression of recombinant expression constructs comprising coding sequenc... | 05/03/2005 |
| 6852846 | Viral amplification of recombinant messenger RNA in transgenic plants A novel method of over expressing genes in plants is provided. This method is based on the RNA amplification properties of plus strand RNA viruses of plants. A chimeric multicistronic gene is constructed containing a plant promoter, viral replication origins, a vira... | 02/08/2005 |
| 6846968 | Production of lysosomal enzymes in plants by transient expression The invention relates to the production of enzymatically active recombinant human and animal lysosomal enzymes involving construction and expression of recombinant expression constructs comprising coding sequences of human or animal lysosomal enzymes in a plant expr... | 01/25/2005 |
| 6800748 | Cytoplasmic inhibition of gene expression and expression of a foreign protein in a monocot plant by a plant viral vector The present invention relates to recombinant viral vectors encoding a transcriptional unit, that encodes a fusion protein, or a foreign protein or a gene of interest to be silenced, which can be expressed in a host. The present invention also relates to the use of t... | 10/05/2004 |
| 6656726 | Viral expression vectors The present invention provides nucleic acid sequences having an altered viral movement protein and 126/183 kDa replicase proteins further characterized in its ability to stabilize a transgene contained in a virus that expresses the altered movement protei... | 12/02/2003 |