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| Number | Title | Issue Date |
| 6492494 | Method of making a fibrin sealant comprising alpha-2-antiplasmin The invention provides a kit for preparing a fibrin sealant either (A) comprising: (a) a fibrin monomer preparation; (b) a stabilizing preparation containing a clot-preserving effective amount of a fibrinolysis-inhibiting protein; and (c) a non-enzymatic ... | 12/10/2002 |
| 6348423 | Multilayered wound dressing A novel wound dressing includes a fibrous absorbent layer for absorbing wound exudate, an odor layer for absorbing odor and a barrier layer interposed the fibrous absorbent and barrier layers. Preferably the barrier layer is vacuum perforated and the fibr... | 02/19/2002 |
| 6270794 | Method and composition for absorbing wound fluids An absorbent wound filler having high capacity for absorbing wound exudate comprising a polymeric matrix having absorbing powders dispersed within the matrix and method of treating an exudating wound by applying the wound filler to the wound. The absorbin... | 08/07/2001 |
| 6268544 | Knitted wound dressings and method for making same The present invention provides a wound dressing comprising a mixture of textile fibres and gel forming fibres wherein the dressing is a knitted fabric comprising support yarn and in-laid yarn, the support yarn being substantially free of gel-forming fibre... | 07/31/2001 |
| 6268483 | Compositions useful as fibrin sealants Novel fibrin monomer compositions which are solutions including additional coharvested components, such as prothrombin and Factor XIII, are useful in fibrin sealant applications. Preferably, the compositions are autologous to the patient receiving the sea... | 07/31/2001 |
| 6235964 | Wound dressing An improved wound dressing is provided which comprises a backing layer bearing a reference marking, a hydrocolloid layer and a release layer. The hydrocolloid swells in use. This swelling can be seen or felt through the backing layer. When the swelling ex... | 05/22/2001 |
| 6179818 | Ostomy bags and vessels for biological materials The invention provides a vessel for biological materials comprising a multilayer polymeric barrier material that has very low permeability to small molecules, such as water and oxygen, high flexibility and softness, and is resistant to tearing. The invent... | 01/30/2001 |
| 6175054 | Water soluble films A water soluble film having a thickness of from 0.03 mm to 0.5 mm comprising a water soluble polymer and an active substance.... | 01/16/2001 |
| 6083902 | Recombinant fibrin chains, fibrin and fibrin-homologs The invention is directed to fibrin materials for use in fibrin compositions and methods that avoid the need to use thrombin as an activating agent for fibrin monomer-based sealants. The invention provides for substantially pure fibrin chains, fibrin chai... | 07/04/2000 |
| 6077507 | Method of making a composition comprising a fibrin monomer The subject invention relates to fibrin sealants. More specifically, the subject invention relates to the use of a fibrin sealant wherein a composition comprising fibrin monomer or a composition comprising noncrosslinked fibrin is utilized as a component ... | 06/20/2000 |
| 6066773 | Thin film dressing with absorbent border A thin film device for medical applications such as a wound dressing including an occlusive layer having an edge portion about at least a portion of the thin film device and a non-continuous, hydrocolloid-containing polymeric support layer overlying the e... | 05/23/2000 |
| 5998155 | Stable composition of immobilized protein having affinity for biotin Compositions and methods for avidin or protein having affinity for biotin immobilized on an inert support material, e.g., agarose, are disclosed. The compositions have high activity levels for binding biotin and may include a bulking agent, e.g., maltose,... | 12/07/1999 |
| 5962026 | Solid compositions of fibrin monomer This invention is directed to solid compositions, for example, lyophilized forms, of fibrin monomer. These compositions are useful wherever fibrin monomer could be employed, e.g., as a surgical sealant to provide hemostasis.... | 10/05/1999 |
| 5962420 | Fibrin sealant compositions and methods for utilizing same The subject invention relates to fibrin sealants. More specifically, the subject invention relates to the use of a fibrin sealant wherein a composition comprising fibrin monomer or a composition comprising noncrosslinked fibrin is utilized as a component ... | 10/05/1999 |
| 5942406 | Gel, slurry or suspension containing immobilized avidin having high biotin binding activity Compositions and methods for avidin immobilized on an inert support material, e.g., agarose, are disclosed. The compositions have high activity levels of avidin and may further include a bulking agent, e.g., maltose, and a protectant to maintain the stabi... | 08/24/1999 |
| 5858253 | Blood separation process In a process of separating a liquid sample having phase portions of different densities by centrifugal separation, a phase separator container is employed. The phase separator container comprises a housing having concentric inner and outer cylindrical wal... | 01/12/1999 |
| 5804428 | Fibrin sealant compositions and methods for utilizing same The invention relates to fibrin sealants. More specifically, the invention relates to the preparation of a fibrin polymer wherein the polymer is substantially free of the enzyme.... | 09/08/1998 |
| 5795780 | Method of use of autologous thrombin blood fraction in a cell culture with keratinocytes The subject invention relates to the use of thrombin in a medical procedure in an animal. More specifically, the subject invention relates to such use of thrombin wherein the thrombin is a thrombin blood fraction, is autologous to that animal.... | 08/18/1998 |
| 5795571 | Composition containing autologous thrombin blood fraction for use in a medical procedure The subject invention relates to the use of thrombin in a medical procedure in an animal. More specifically, the subject invention relates to such use of thrombin wherein the thrombin is a thrombin blood fraction is autologous to that animal.... | 08/18/1998 |
| 5773418 | Fibrin sealant compositions and methods for utilizing same The subject invention relates to fibrin sealants. More specifically, the subject invention relates to the use of a fibrin sealant wherein a composition comprising fibrin monomer or a composition comprising noncrosslinked fibrin is utilized as a component ... | 06/30/1998 |
| 5770194 | Fibrin sealant compositions and methods for utilizing same The subject invention relates to fibrin sealants. More specifically, the subject invention relates to the use of a fibrin sealant wherein a composition comprising fibrin polymer is utilized as a component of the fibrin sealant.... | 06/23/1998 |
| 5763410 | Kit for preparing a fibrin sealant Novel kits for the preparation of a fibrin sealant are disclosed. In one kit a first component is fibrin monomer which can be polymerized to form a fibrin sealant when combined with the second component which is distilled water or an alkaline buffer.... | 06/09/1998 |
| 5763411 | Nondynamic fibrin monomer on bandages, sutures, prostheses and dressings The present invention relates to a solid support, e.g., a suture, bandage, dressing or prosthesis, and a nondynamic fibrin monomer. The nondynamic fibrin monomer is readily capable of being converted to a fibrin polymer which has sealant and hemostasis pr... | 06/09/1998 |
| 5739288 | Fibrin sealant compositions The invention relates to fibrin sealants. More specifically, the invention relates to the use of a fibrin sealant wherein a composition comprising fibrin monomer or a composition comprising noncrosslinked fibrin is utilized as a component of the fibrin se... | 04/14/1998 |
| 5716987 | Prophylactic and therapeutic treatment of skin sensitization and irritation Methods, compositions and systems for preventing an adverse reaction of the skin to the presence of a skin-sensitizing and/or skin-irritating agent by administering an effective amount of phenoxyacetic acid and/or a lower alkyl ester thereof to a warm blo... | 02/10/1998 |
| 5714543 | Water soluble polymer additives for polyurethane-based pressure sensitive adhesives In accordance with the present invention novel polyurethane PSAs containing water soluble polymer additives have enhanced water uptake. The water soluble polymer additives suitable for use herein have a solubility parameter in poorly hydrogen-binding solv... | 02/03/1998 |
| 5714232 | Alginate fabric, its use in wound dressings and surgical haemostats and a process for its manufacture The invention is a wound dressing prepared from alginate fibers which have good structural integrity, whereby layers are firmly joined together, e.g. by stitching or calendering at a plurality of points to produce a composite fabric.... | 02/03/1998 |
| 5691152 | Stable avidin composition Compositions and methods for avidin immobilized on an inert support material, e.g., agarose, are disclosed. The compositions have high activity levels of avidin and may further include a bulking agent, e.g., maltose, and a protectant to maintain the stabi... | 11/25/1997 |
| 5690955 | Sustained release alginate fibre and process for the preparation thereof An alginate fibre is provided which includes one or more medicaments incorporated into the fibre core such that the one or more medicaments can be released in a sustained manner over time and, optionally, one or more medicaments attached to the surface of... | 11/25/1997 |
| 5670169 | Wound hydrating gel with novel preservative system and low cytotoxicity The present invention relates to a preserved, yet non-cytotoxic alginate based hydrating gel system for the purpose of treating wounds that need moisture. Sodium carboxymethylcellulose and an alginate polymer blend impart sufficient viscosity to an aqueou... | 09/23/1997 |
| 5618557 | Prophylactic treatment of allergic contact dermatitis Methods and devices for preventing an adverse reaction of the skin to the presence of a skin-sensitizing agent by administering an effective amount of a potassium-sparing diuretic.... | 04/08/1997 |
| 5605541 | Fibrin sealant applicatoor A novel device and method for the application of two or more components of a fibrin sealant using a gas is disclosed. The novel device and method involve the concentric arrangement of annular apertures for each of the components concentric with and radial... | 02/25/1997 |
| 5603845 | Liquid separation apparatus and method In a process of separating a liquid sample having phase portions of different densities by centrifugal separation, a phase separator container is employed. The phase separator container comprises a housing having concentric inner and outer cylindrical wal... | 02/18/1997 |
| 5603946 | Wound dressing A novel two piece dressing having a baseplate and wound fluid absorbing material is provided according to the present invention. The baseplate is provided with slits or incisions for covering, examining and/or treating the wound without removing the basep... | 02/18/1997 |
| 5599289 | Medical dressing with semi-peripheral delivery system In accordance with the present invention novel medical dressing systems and methods are disclosed using a semiperipheral support design which provides at least one conformal, unsupported dressing edge upon application. The dressing system disclosed herein... | 02/04/1997 |
| 5591820 | Polyurethane pressure-sensitive adhesives Pressure-sensitive adhesives which possess absorptivity and/or permeability properties to remove transepidermal water loss and/or other bodily fluids that come into contact with the adhesive, in combination with a fine balance of cohesion and adhesion pro... | 01/07/1997 |
| 5580573 | Temperature activated controlled release A polymeric device for the controlled release of active agents contained in the device in which the polymer has a glass transition temperature greater than the normal storage or non use temperature of the device. When heated to or above the glass transiti... | 12/03/1996 |
