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| Number | Title | Issue Date |
| 6821732 | Methods and compositions in breast cancer diagnosis and therapeutics The present invention is directed to compositions regarding a specific mutation in estrogen receptor alpha and their use as diagnostic markers in breast tissue, such as premalignant lesions, for the development of breast cancer. More specifically, cells of breast ca... | 11/23/2004 |
| 6656512 | Pet food product with coconut endosperm fiber The present invention relates to the use of coconut endosperm fiber as a dietary fiber component in a pet food product, to the use of coconut endosperm fiber in the manufacture of a pet food product, to a pet food product which comprises coconut endosperm... | 12/02/2003 |
| 6632656 | Microfabricated apparatus for cell based assays Apparatus and methods are provided for performing cell growth and cell based assays in a liquid medium. The apparatus comprises a base plate supporting a plurality of micro-channel elements, each micro-channel element comprising a cell growth chamber, an ... | 10/14/2003 |
| 6605711 | NY-ESO-1 peptide derivatives, and uses thereof The invention relates to variant peptides which bind to HLA molecules, leading to lysis of cells via cytolytic T cell lines. The variants are based upon NY-ESO-1 peptides. The peptides can be incorporated into immune tetramers, which are useful as T cell ... | 08/12/2003 |
| 6573100 | DNA vectors without a selection marker gene The use of a circular vector DNA to produce a pharmaceutical agent for the treatment of mammals or humans by gene therapy wherein the vector DNA contains a selection marker gene and a DNA sequence that is heterologous for the vector which causes a modulat... | 06/03/2003 |
| 6538174 | Animal model for transplantation The invention relates to an animal model of cancer. The animal carries a tumor xenograft and is immunosuppressed by administration of cyclosporin and ketoconazole. The model is useful for studying cancer and treatment thereof.... | 03/25/2003 |
| 6531280 | Method for identifying or isolating a molecule and molecules identified thereby The invention described methods for identifying a molecule of interest, as well as nucleic acid molecules which encode it, and binding partners for it. A cDNA library from a cell expressing the target is prepared, and expressed in host cells. Lysates of t... | 03/11/2003 |
| 6518415 | Recombinant human anti-Lewis Y antibodies The invention provides for the production of several humanized murine antibodies specific for the antigen Lewis Y, which is recognized by the murine antibody Lewis Y. The Lewis Y antigen is expressed in normal tissues but the level of expression is higher... | 02/11/2003 |
| 6509172 | Isolated, truncated nucleic acid which are members of the gage, and uses thereof The invention relates to new members of the GAGE family referred to as GAGE-7B and GAGE-8. There are differences between these two molecules and the previously described members of the GAGE family on the genomic DNA, complementary DNA, and amino acid leve... | 01/21/2003 |
| 6506875 | Isolated peptides which bind to HLA-C molecules and uses thereof The invention teaches peptide epitopes which bind to HLA-Cw3 and HLA-Cw6 molecules on the surface of cells. The peptides are useful diagnostically and therapeutically, as are DNA molecules which encode them, and the cytolytic T lymphocytes specific to the... | 01/14/2003 |
| 6117233 | Formation of single-crystal thin SiC films Thin, single-crystal SiC films are obtained by means of a pyrolysis process, the substrate to be coated being covered with a carbonaceous polysilane, the adhering layer being pyrolyzed in an inert atmosphere and the amorphous layer of SiC obtained in this... | 09/12/2000 |
| 6062658 | Method and apparatus for controlling the brake system of a vehicle In a vehicle having a duty brake and a sustained-action brake (retarder), the actual braking moment produced by the sustained-action brake, as well as the braking command of the driver, are taken into consideration in the electrically controlled adjustmen... | 05/16/2000 |
| 6013481 | Isolated, nucleic acid molecules which code for gage tumor rejection antigen, the tumor rejection antigen, and uses thereof A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules whic... | 01/11/2000 |
| 5997872 | Isolated nucleic acid molecule coding for tumor rejection antigen precursor MAGE-C1 and uses thereof The invention relates to an isolated DNA sequence which codes for an antigen expressed by tumor cells which maybe recognized by cytotoxic T cells, leading to lysis of the tumor cells which express it. This invention also relates to vectors which are desig... | 12/07/1999 |
| 5992322 | Waterless lithographic printing plate having a cyanoacrylate image A substrate is coated with a first material which is soluble in a first solvent, whereupon a second material which is strongly adherent to the first material and insoluble in the first solvent is selectively applied by an ink jet printer. The substrate is... | 11/30/1999 |
| 5972646 | Isolated nucleic acid molecule which codes for a 32 kDa protein having 11-cis retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor In accordance with this invention, an RPE cell membrane associated protein which has a molecular weight of about 32 kd, as determined by SDS-PAGE, has been discovered. This protein, referred to an "p32," forms an oligomeric protein complex with the previo... | 10/26/1999 |
| 5970213 | Apparatus for heating a transparent substrate utilizing an incandescent lamp and a heating disk emitting infrared wavelengths A heating disk is located inside a vacuum chamber between a substrate holder inside the chamber and a lamp outside the chamber. The lamp emits radiation in a wavelength range which passes through a glass plate in the chamber wall but is absorbed by the he... | 10/19/1999 |
| 5962115 | Pane of transparent material having a low emissivity A system of layers applied to a transparent substrate includes a first layer of an oxide such as ZnO or SnO2, a second layer of a substoichiometric oxide of Zn or Ta, a third layer of Ag or Cu, a fourth layer of a substoichiometric oxide of Ti,... | 10/05/1999 |
| 5955271 | Method and kits for determining messenger RNA molecules in a sample The invention involves methods and kits useful in determining specific mRNA molecules. The methods can be carried in a single reaction vessel, in that both reverse transcriptase and amplification can be carried out in the same, heat stable reaction vessel... | 09/21/1999 |
| 5952799 | Electrical brake system An electronic brake system for a vehicle which has control modules for adjusting the braking force at the wheels of the vehicle, a control module which determines at least the driver's braking command, and at least one communications system which connects... | 09/14/1999 |
| 5952484 | Recombinant human anti-LK26 antibodies The invention provides for the production of several humanized murine antibodies specific for the antigen LK26, which is recognized by the murine antibody LK26. This antigen is expressed on all choriocarcinoma, teratocarcinoma and renal cancer cell lines ... | 09/14/1999 |
| 5952228 | Isolated cytolytic T cells which are specific for complexes OF HLA- B35 molecules and the peptide PHE Pro Ser Asp Ser Trp Cys Tyr PHE, and uses thereof The invention relates to isolated cytolytic T cells which recognize complexes of HLA-B35 molecules and the peptide defined by SEQ ID NO: 2, as well as methods for identifying HLA-B35 positive cells. The method involves contacting the cytolytic T cells to ... | 09/14/1999 |
| 5944967 | Dual target cathode assembly with shielding A dual magnetron cathode assembly includes a pair of elongate, parallel targets in coplanar relationship fixed to respective magnetic yokes with associated rows of permanent magnets for producing a magnetic field over the targets. A common back plate is p... | 08/31/1999 |
| 5939175 | Method of finishing heat-reinforced plate glass and edge regions thereof Diclosed is a plate glass wherein surfaces (3a) of plate glass (3) are formed flat and finished with a maximum surface ruggedness not exceeding 0.05 mm, and boundaries (3c) between end surfaces (3a) and front and back surfaces (3b) of the plate glass (3) ... | 08/17/1999 |
| 5935929 | Methods for treating interstitial lung disease by using interleukin-9 and its antagonists A method for the treatment and prevention of immune disorders and fibrosis associated disorders is disclosed. The method involves administering interleukin-9 in an effective amount to the subject. Among the conditions treatable are thyroiditis, autoimmune... | 08/10/1999 |
| 5932249 | Budesonide pellets with a controlled released pattern and process for producing the same Disclosed are budesonide pellets with a controlled release pattern containing, from the inside to the outside: a) neutral pellets; b) an active principle layer of micronized budesonide and one or more water-soluble auxiliaries; c) a first lacquer coating ... | 08/03/1999 |
| 5933566 | Film analyzer A film analyzer for displaying print images simulated from picture frames of a photographic film on a video display. The analyzer includes a film reader for picking up image data of the picture frames, a first memory for storing the picked-up image data, ... | 08/03/1999 |
| 5928938 | Isolated peptides which complex with HLA-Cw*16 molecules, and uses thereof The invention involves the identification of peptides which complex with HLA-Cw.sup.* 16 molecules, and which may then provoke lysis of the cells to which they bind, by cytolytic T cells. Diagnostic and therapeutic uses are described.... | 07/27/1999 |
| 5923405 | Method and system for specifying position of frame to be printed in film piece A film holder holds a plurality of film pieces which are obtained by cutting a film having a plurality of frames between the forward and rear longitudinal ends. The film pieces are cut from the film in such a manner that the first and the last two pieces ... | 07/13/1999 |
| 5916478 | Heat-accumulating microcapsule dispersion Heat-accumulating microcapsule dispersion includes a microcapsule provided as a small-diameter heat-accumulating material including organic compound functioning as heat accumulating material in association with a phase change thereof accommodated within a... | 06/29/1999 |
| 5913654 | Lateral shifting system for floor transport vehicles Disclosed is a lateral shifting system for a floor transport vehicle, which has a lift carriage with a base frame with one upper and one lower hook edge for mounting fork tines and has a lateral shift frame. The lateral shift frame has two horizontal fram... | 06/22/1999 |
| 5913321 | One-handed control stick umbrella A stick umbrella capable of being opened and closed by one hand having a stem, a crown, a runner, main ribs, and stretchers constituting a frame; an elongated slide which is slidably arranged along the stem and carries at the upper end a notch member to w... | 06/22/1999 |
| 5910239 | Potentiometric CO2 sensor having an open titanate- or stannate-based reference electrode The invention relates to a a reference electrode for electrolytic cells, comprising a combination of (a) titanium dioxide and an alkali-metal or alkaline-earth-metal titanate or (b) tin dioxide and an alkali-metal or alkaline-earth-metal stannate as a hom... | 06/08/1999 |
| 5906991 | Process for the manufacture of flavanolignan preparations with improved release and absorbability, compositions obtainable thereby and their use for the preparation of pharmaceuticals The present invention provides a process for the production of a flavanolignan preparation with an improved liberation in comparison with one of the pure flavanolignans, characterized in that a) an aqueous-alcoholic solution of pharmaceutically-acceptable... | 05/25/1999 |
| 5902733 | Test system for determining the activity of natural killer cells The invention concerns a method for determining the action of effectors on target cells, wherein thawed cryopreserved mammalian cells are used without prior culture as target cells which have a vitality of at least 85% after storage at -70° C. for a peri... | 05/11/1999 |
| 5902397 | Crystal holder In an apparatus for the production of single crystals (103) by the Czochralski melt drawing method, a gripping device (125a, 125b) is provided, by means of which the crystal (103) is held during the growing process by a pressure which is exerted radially ... | 05/11/1999 |
| 5898127 | Apparatus for shielding against high-frequency electromagnetic radiation A cover fitted about the periphery of an opening in a chamber wall is provided with a channel having therein both high frequency sealing elements which prevent escape of electromagnetic radiation, and a vacuum sealing element. The HF sealing elements are ... | 04/27/1999 |
| 5897141 | File stiffener The invention relates to a file stiffener for stiffening a file of the type having a pair of opposed covers hinged to and spaced apart from one another by a spine, in particular for ring binder and lever arch-type files. The file stiffener comprises at le... | 04/27/1999 |
| 5888751 | Method for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells The invention involves the recognition of a previously identified protein, SCP-1, as a marker for cell transformation. Diagnostic and therapeutic uses of this protein and related molecules are taught. Also disclosed is a method for identifying substances ... | 03/30/1999 |
| 5874060 | Recombinant human anti-Lewis Y antibodies The invention provides for the production of several humanized murine antibodies specific for the antigen Lewis Y, which is recognized by the murine antibody Lewis Y. The Lewis Y antigen is expressed in normal tissues but the level of expression is higher... | 02/23/1999 |
