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Lawrence Welk, the bandleader who entertained millions of Americans over a generation of broadcasting his TV show, once received a patent: for a music-themed design of an ashtray.
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| Number | Title | Issue Date |
| 8173180 | Stabilized anthocyanin compositions The invention describes stabile anthocyanin compositions, methods to prepare such compositions and also methods of use of such compositions to treat various afflictions. The present invention describes unique compositions of an anthocyanin and a stabilizing compound... | 05/08/2012 |
| 8168848 | Access openings in vacuum bandage A wound dressing member is provided for use in a vacuum bandage connected to a vacuum source and for use with a wound having a wound surface. The member may include a top surface and a bottom surface adapted to be in contact with and generally conform to the wound s... | 05/01/2012 |
| 8163881 | Immunoglobulin molecules with improved characteristics The present invention provides for IgG1 molecules with improved characteristics. In particular, substitution mutations are provided that, in combination, facilitate improved placental transfer, improved serum half-life and improved FcRn binding. Substitution mutatio... | 04/24/2012 |
| 8163709 | TAK1-D mediated induction of cell death in human cancer cells by specific sequence short double-stranded RNAS The splicing variant D of the TAK1 gene is activated by short double-stranded RNAs in a sequence specific manner. Activation of TAK1-D leads to the downstream activation of the p38 MAPK and of SAPK/JNK but not the NFκB pathway. The current invention therefore provi... | 04/24/2012 |
| 8153368 | Four-jointed box (FJX1) in cancer diagnosis and treatment The present invention relates to a new tumor suppressor, designated FJX1. Also described are diagnostic, prognostic and therapeutic uses of the FJX1 protein and the FJX1 gene, alone or in combination with traditional cancer therapies. ... | 04/10/2012 |
| 8153168 | Stabilized anthocyanin Compositions The invention describes stabile anthocyanin compositions, methods to prepare such compositions and also methods of use of such compositions to treat various afflictions. The present invention describes unique compositions of an anthocyanin and a stabilizing compound... | 04/10/2012 |
| 8147881 | Stabilized anthocyanin compositions The invention describes stabile anthocyanin compositions, methods to prepare such compositions and also methods of use of such compositions to treat various afflictions. The present invention describes unique compositions of an anthocyanin and a stabilizing compound... | 04/03/2012 |
| 8142501 | Artificial ligaments and tendons comprising multifilaments and nanofibers and methods for making Prosthetic ligaments and tendons comprising ligament- or tendon-mimicking nanofibers and methods of making such nanofibers and prosthetic ligaments and tendons. ... | 03/27/2012 |
| 8142365 | Apparatus and method for accessing the bone marrow of the sternum An apparatus and method for accessing the bone marrow of a human's sternum is provided. The apparatus includes a tissue penetrator configured to penetrate the sternum, a trigger mechanism configured to engage when the tissue penetrator contacts the sternum and a dep... | 03/27/2012 |
| 8129506 | Modulation of the interaction of MUC1 with MUC1 ligands The present invention provides for chimeric proteins comprising a MUC1 extracellular (MUC1-EC) polypeptide and a carrier polypeptide that function as traps for MUC1 ligands. ... | 03/06/2012 |
| 8129345 | MUC1-IκB kinase complexes and their activities The disclosure provides methods of identifying and making compounds and pharmaceutical compositions containing the compounds that inhibit the interaction between MUC1 and an IKK. The disclosure also provides in vivo and in vitro methods of inhibiting such an interac... | 03/06/2012 |
| 8129161 | Bardet-Biedl susceptibility gene and uses thereof The present invention relates to the identification of a gene, now designated negevin (ngvn), that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypertension, mental retardation,... | 03/06/2012 |
| 8128970 | Sesame seed derived pigments The invention describes reduced sesame seed derived pigments and methods to prepare such pigments. ... | 03/06/2012 |
| 8124355 | Detection and identification of groups of bacteria The present invention concerns a method for the simultaneous detection of different bacteria, comprising the following steps: coupling one or more species of bacteriophage tail proteins onto a support, incubating the support coupled with the bacteriophage tail prote... | 02/28/2012 |
| 8119691 | Method for treating airway hyper-responsiveness with lipoxin analogs The use of lipoxin analogs for the treatment or prevention of asthma and asthma related diseases is described. In particular, acetylenic lipoxin analogs are effective for the treatment and prevention of eosinophil recruitment involved with the inflammation processes... | 02/21/2012 |
| 8119656 | Inhibitors of the influenza virus non-structural 1 protein The present invention generally relates to compounds to treat viral infections and methods of their use. In particular, compounds of the present invention inhibit the activity of NS1 protein, thereby mitigating viral infection and, in particular, influenza virus inf... | 02/21/2012 |
| 8119365 | Insertion sequence-free bacteria A bacteria lacking genomic and non-genomic IS elements is provided. The bacteria may be more stable and useful for the production of amino acids, polypeptides, nucleic acids and other products. ... | 02/21/2012 |
| 8107714 | Methods for detecting and tagging scene changes Methods for determining a difference between a reference scene and a test scene are provided. An automated process calculates a power of the reference scene and a power of the test scene. The difference between the power of the reference scene and the test scene det... | 01/31/2012 |
| 8104753 | Support means Support means are provided for supporting one or more items in use. The support means includes at least first and second members and at least one of said first and second member movable relative to the other member to allow clamping and/or unclamping on an item loca... | 01/31/2012 |
| 8101371 | Methods for the diagnosis of genitourinary cancer Methods for the diagnosis of genitourinary (GU) cancer are provided. In particular, urine has been found to contain significant levels of thromboxane receptor β (TPβ) methods for diagnosing GU cancer. Methods for assessing treatment, prognosing and staging GU canc... | 01/24/2012 |
| 8093053 | Methods and compositions for culturing of neural precursor cells The present invention provides methods and compositions for the propagation and expansion of neural precursor cells (NPCs). NPCs may be used in the clinical implementation of stem cell therapy to treat disorders such as Parkinson's disease, Huntington's disease, neu... | 01/10/2012 |
| 8092881 | Multi-layered fuel tubing The invention describes a flexible tubular article for transport of volatile hydrocarbons comprising: (a) an inner layer of a polyvinylidene difluoride (PVDF) polymer or a polyvinylidene difluoride copolymer; (b) an intermediate thermoplastic polyurethane (TPU) laye... | 01/10/2012 |
| 8092842 | Extraction of phytochemicals by enzymatic hydrolysis A process for extracting phytochemicals from plants. The process generally comprises controllably slurrying a selected plant material in a volume, adding a selected enzyme the slurry while it is controllably agitated, then heating the controllably agitated slurry-en... | 01/10/2012 |
| 8071152 | Methods involving whey protein isolates The present invention concerns methods and compositions that involve whey protein isolates. Methods of the invention include purification processes for preparing whey proteins that are substantially nondenatured across a range of pH, including their isoelectric poin... | 12/06/2011 |
| 8058225 | Proteins for use in human and animal infections The present invention relates to a polypeptide termed ply_pitti26 comprising the sequence as depicted in SEQ ID NO:1 as well as variants of this polypeptide. Furthermore, the present invention relates to nucleic acids and vectors encoding for said polypeptide and va... | 11/15/2011 |
| 8056624 | In Situ heavy oil and bitumen recovery process The present invention is directed to an in situ reservoir recovery process that uses a horizontal well located near the top of a reservoir and an inclined production well to extract bitumen or heavy oil from a reservoir. In a first stage, the top well is used for co... | 11/15/2011 |
| 8043842 | Bacteria with reduced genome The present invention provides a bacterium having a genome that is genetically engineered to be at least 2 to 14% smaller than the genome of its native parent strain. A bacterium with a smaller genome can produce a commercial product more efficiently. The present in... | 10/25/2011 |
| 8039243 | Insertion sequence-free bacteria The present invention provides a bacterium having a genome that is genetically engineered to be smaller than the genome of its native parent strain. A bacterium with a smaller genome can produce a commercial product more efficiently. The present invention also provi... | 10/18/2011 |
| 8034983 | Process for the preparation of xanthophyll crystals The invention describes the preparation and isolation of xanthophylls from plant sources, whereby a transesterification process is utilized without the necessity of an aqueous format. ... | 10/11/2011 |
| 8034143 | Cyclone A cyclone includes a cylindrical housing and has an inner diameter D. An inlet is near a first end of the housing. A deflection member can be positioned within the first end or the second end of the housing, depending on whether the cyclone is uniflow or reverse flo... | 10/11/2011 |
| 8031338 | Measuring Forster resonance energy transfer with polarized and depolarized light The present invention provides improved methods for assessing Förster resonance energy transfer using polarized light. Specifically, the methods rely on measuring depolarized light emitted by fluorescent acceptor molecules. ... | 10/04/2011 |
| 8022105 | Prevention of neutrophil recruitment Aspirin (ASA) triggers a switch in the biosynthesis of lipid mediators, inhibiting prostanoid production and initiating 15-epi-lipoxin generation, through the acetylation of cyclooxygenase II. ... | 09/20/2011 |
| 8021348 | Wound treatment apparatus An apparatus comprising a housing, a controller, a fluid source, a negative pressure source, and a canister. The controller, the fluid source, the negative pressure source, and the canister are carried by the housing. The fluid source is couplable to the bandage. Th... | 09/20/2011 |
| 8017315 | Mitochondrial localization of MUC1 The invention provides methods of identifying and making compounds that inhibit the interaction between MUC1 and either or both of HSP70 and HSP90. Also embraced by the invention are in vivo and in vitro methods of inhibiting such an interaction. ... | 09/13/2011 |
| 8012695 | Methods and compositions relating to promoter regulation by MUC1 and KLF proteins This invention relates to regulation of cell signaling, cell growth, and more particularly to the regulation of cancer or inflammatory cell growth and/or activation. The invention provides methods of, and compositions useful for, inhibiting interactions between MUC1... | 09/06/2011 |
| 8012483 | Phosphorylcholine conjugates and corresponding antibodies IgG and IgM autoantibody levels against phosphorylcholine in subjects with hypertension (diastolic pressure >95 mmHg) were determined at baseline in order to determine the importance of antibodies for the development of atherosclerosis. The results show that increas... | 09/06/2011 |
| 8009278 | Customizable spectral profiles for filtering Computer program products comprising tangible computer-readable media having instructions that are executable by a computer to generate a customized spectral profile, which can be used to generate a corresponding filter. The instructions can comprise: generating a t... | 08/30/2011 |
| 8008282 | Lipoxin analogs as novel inhibitors of angiogenesis The present invention is directed to methods for the prevention or inhibition of angiogenesis. The method is accomplished by the administration of an effective amount of 15-epi-16-(para-fluoro)-phenoxy-lipoxin A4, LXA4, 15-epi-LXA4 o... | 08/30/2011 |
| 8008013 | Predicting and diagnosing patients with autoimmune disease The present invention provides methods for the prediction and diagnosis of autoimmune diseases, including Systemic Lupus Erythematosus, using single nucleotide polymorphism in TNFAIP3 (A20). ... | 08/30/2011 |
| 8007994 | Compositions and methods of modulating cholesterol metabolism The present invention relates to compositions and methods for reducing cholesterolemia and its effects. More specifically, the invention is directed, in one embodiment, to methods for screening for compounds that affect cholesterol levels generally, and in particula... | 08/30/2011 |
