...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 8092395 | Guide wire for use in re-canalising a vascular occlusion in a human or animal subject A guidewire (1) for re-canalizing a vascular occlusion comprises a core wire (5) which terminates at its distal end (4) in a terminal member (7) for opening the occlusion. A helical coil sleeve (10) extends around the core wire ( | 01/10/2012 |
| 8048972 | Nanohybrid polymers for ophthalmic applications The present invention relates to novel materials particularly useful for ophthalmic applications and methods for making and using the same. More particularly, the present invention relates to relatively soft, optically transparent, foldable, high refractive index ma... | 11/01/2011 |
| 8034106 | Interfacial refraction accommodating lens (IRAL) This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any othe... | 10/11/2011 |
| 7893080 | Method of restoring the incretin effect The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon l... | 02/22/2011 |
| 7857850 | Interfacial refraction accommodating lens (IRAL) This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any othe... | 12/28/2010 |
| 7857848 | Infinite refractive index gradient (IRIG) polymers for ocular implant and contact lens applications Infinite gradient refractive index ophthalmic devices and methods of making same. The method involves diffusing a monomer which polymerizes to a lower or higher corresponding opposite refractive index polymer into a lower or higher index polymer structure and polyme... | 12/28/2010 |
| 7842367 | Ultra violet, violet, and blue light filtering polymers for ophthalmic applications Opthalmic devices, particularity intraocular lenses (IOL), with improved contrast sensitivity and methods of making same. In one aspect, blue light blocking chromophores (BLBC) are diffused into, e.g. an IOL lens body to create a BLBC gradient in the lens. Orange dy... | 11/30/2010 |
| 7807191 | Apparatus and methods for preventing or treating failure of hemodialysis vascular access and other vascular grafts This invention is a prosthetic device generally placed on the outside surface of the vessel or graft which then elutes antiproliferative drugs or agents from a drug-eluting matrix material. Methods of perivascular antiproliferative drug administration also are discl... | 10/05/2010 |
| 7789839 | Guide wire for use with a catheter A guide wire (1) for use with a catheter for accessing a remote site in the venal or other system of the body of a human or animal subject comprises a core wire (2) extending from a proximal end (5) to a distal end (6). The core wire (... | 09/07/2010 |
| 7745555 | Nanohybrid polymers for ophthalmic applications The present invention relates to novel materials particularly useful for ophthalmic applications and methods for making and using the same. More particularly, the present invention relates to relatively soft, optically transparent, foldable, high refractive index ma... | 06/29/2010 |
| 7446157 | Nanohybrid polymers for ophthalmic applications The present invention relates to novel materials particularly useful for ophthalmic applications and methods for making and using the same. More particularly, the present invention relates to relatively soft, optically transparent, foldable, high refractive index ma... | 11/04/2008 |
| 7399811 | Nanohybrid polymers for ophthalmic applications The present invention relates to novel materials particularly useful for ophthalmic applications and methods for making and using the same. More particularly, the present invention relates to relatively soft, optically transparent, foldable, high refractive index ma... | 07/15/2008 |
| 7354980 | High refractive index polymers for ophthalmic applications This invention relates to novel copolymers preferably for intraocular lenses (“IOL”), contact lens, and other ophthalmic and optical applications. This invention, in one aspect, relates to copolymer compositions comprising limited amounts of a monomer hav... | 04/08/2008 |
| 7067511 | Pyrrolobenzodiazepines Compounds of the formulae Ia and Ib: wherein: A is CH2, or a single bond; R2 is selected from: R, OH, OR, CO2H, CO2R, COH,... | 06/27/2006 |
| 7008771 | Multiplex amplification of short tandem repeat loci Methods and materials are disclosed for use in simultaneously amplifying at least thirteen loci of genomic DNA in a single multiplex reaction, as are methods and materials for use in the analysis of the products of such reactions. Included in the present invention a... | 03/07/2006 |
| 6884233 | Thrombolysis catheter system with fixed length infusion zone A thrombolysis catheter system having a fixed length infusion zone is disclosed. The invention contemplates apparatus, method and kit aspects. The apparatus, which has the capability to track a guidewire, uses a multilumen catheter to deliver radially thrombolytic a... | 04/26/2005 |
| 6844152 | Detection of microsatellite instability and its use in diagnosis of tumors Methods and kits are disclosed for use in the analysis of microsatellite instability in genomic DNA. Methods and kits are also disclosed which can be used to detect microsatellite instability DNA present in biological materials, such as tumors. The methods and kits ... | 01/18/2005 |
| 6806362 | pH dependent ion exchange matrix and method of use in the isolation of nucleic acids Disclosed are pH dependent ion exchange matrices, methods of making, and methods of use. ... | 10/19/2004 |
| 6787307 | Lysate clearance and nucleic acid isolation using silanized silica matrices A method is provided for using a silanized silica matrix to isolate a target nucleic acids, such as plasmid DNA, fragments of DNA, chromosomal DNA, or RNA from contaminants, including proteins, lipids, cellular debris, or non-target nucleic acids. The silanized sili... | 09/07/2004 |
| 6767703 | Materials and methods for identifying and analyzing intermediate tandem repeat DNA markers The present invention is directed to materials and methods for the identification and analysis of intermediate tandem repeat sequences in DNA, wherein an intermediate tandem repeat (ITR) sequence is a region of a DNA sequence containing at least one five to seven ba... | 07/27/2004 |
| 6764689 | High level expression and facile purification of proteins, peptides and conjugates for immunization, purification and detection applications A process for producing and purifying peptides and for producing peptide/protein antigens for antibody production is described. The process utilizes fusion proteins and specifically fusion proteins in which the fusion protein carrier segment includes an amino acid s... | 07/20/2004 |
| 6747144 | Collections of compounds A compound of formula (I), wherein: R2 and R3 are independently selected from H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2 | 06/08/2004 |
| 6726923 | Apparatus and methods for preventing or treating failure of hemodialysis vascular access and other vascular grafts This invention is a prosthetic device generally placed on the outside surface of the vessel or graft which then elutes antiproliferative drugs or agents from a drug-eluting matrix material. Methods of perivascular antiproliferative drug administration also are discl... | 04/27/2004 |
| 6725090 | Electrotransport system having flexible means An apparatus for the electrically assisted delivery of therapeutic agent is described. An apparatus of the invention has rigid zones or regions which are physically connected by flexible means such as a web. The flexible means permits the rigid zones to move indepen... | 04/20/2004 |
| 6711949 | Remote fluid level detection system A remote two-module electronic fluid monitoring system to be used as an agricultural aid in the application of a fluid to a field. A tank module sits atop a field tank and monitors internal fluid level. Fluid level detection is achieved by tracking the position of a... | 03/30/2004 |
| 6698056 | Butterfly sponge mop with angle-adjustable handle A butterfly sponge mop (1) which has a mop handle (2) which can be set at a desired angle with respect to the wings (12,14) of the mop. The handle is attached to a swivel housing (34) which is provided between the wings, by a swivel connector (32) provide... | 03/02/2004 |
| 6694559 | Toilet brush A toilet brush having a frame member (1), a handle portion (3) and a brush portion (5). The brush portion includes front bristles (13) for cleaning a toilet bowl and rearwardly extending bristles (15) for cleaning the lip of a toilet. The bristles and a s... | 02/24/2004 |
| 6694823 | Apparatus and method for testing material performance There is provided an apparatus (LCPA) for measuring a load applied to a quantity of material. The LCPA includes a load cell assembly sandwiched between an inner plate and an outer plate. The load cell assembly measures the load applied to the quantity of ... | 02/24/2004 |
| 6670393 | Carbamate-based cationic lipids The present invention provides novel carbamate-based cationic lipids of the general structure: ##STR1## or a salt, or solvate, or enantiomers thereof, wherein (a) R1 is a lipophilic moiety; (b) R2 is a positively charged moiety; ... | 12/30/2003 |
| 6664269 | Isoquinolinone derivatives Derivatives of isoquinolinone and dihydrolisoquinolinone, and related compounds, and their use as pharmaceuticals in the treatment of a disease by inhibition of the enzyme poly(ADP-ribose)polymerase ("PARP") are disclosed.... | 12/16/2003 |
| 6638529 | Amide-based cationic lipids The present invention provides novel amide-based cationic lipids of the general structure: ##STR1## or a salt, or solvate, or enantiomers thereof wherein; (a) Y is a direct link or an alkylene of 1 to about 20 carbon atoms; (b) R1 is H or a ... | 10/28/2003 |
| 6635732 | Water plasticized high refractive index polymer for ophthalmic applications A high refractive index, foldable polymer suitable for use in ophthalmic devices, such as intraocular lenses, is provided. The polymer may be produced from a polymerization reaction of first, second and third monomeric components and a crosslinking agent.... | 10/21/2003 |
| 6613192 | Process for producing biokraft pulp from eucalyptus chips A method for producing paper pulp for use in the making of paper from eucalyptus wood chips. The method comprises inoculating wood chips with white rot fungi, fermenting the wood chips so as to cause a propagation of the fungus through the wood chips and ... | 09/02/2003 |
| 6610657 | Alkyl peptide amides and applications Disclosed are alkyl peptide amides capable of inhibiting or reducing sperm cell motility. Methods of inhibiting or reducing sperm motility using certain alkyl peptide amides are also disclosed.... | 08/26/2003 |
| 6238863 | Materials and methods for indentifying and analyzing intermediate tandem repeat DNA markers The present invention is directed to materials and methods for the identification and analysis of intermediate tandem repeat sequences in DNA, wherein an intermediate tandem repeat (ITR) sequence is a region of a DNA sequence containing at least one five ... | 05/29/2001 |
| 6113576 | Thrombolysis catheter system with fixed length infusion zone A thrombolysis catheter system having a fixed length infusion zone is disclosed. The invention contemplates apparatus, method and kit aspects. The apparatus, which has the capability to track a guidewire, uses a multilumen catheter to deliver radially thr... | 09/05/2000 |
| 6069230 | High level expression and facile purification of proteins, peptides and conjugates for immunization, purification and detection applications A process for pro and purifying peptides and for producing peptide/protein antigens for antibody production is described. The process utilizes fusion proteins and specifically fusion proteins in which the fusion protein carrier segment includes an amino a... | 05/30/2000 |
| 6034135 | Dimeric cationic lipids The present invention provides novel dimeric cationic lipids. The present invention further provides compositions of these lipids with anionic or polyanionic macromolecules, methods for interfering with protein expression in a cell utilizing these composi... | 03/07/2000 |
| 5981235 | Methods for isolating nucleic acids using alkaline protease Solutions containing nucleic acids are treated with an alkaline protease to digest proteins such as nucleases that degrade the nucleic acids. In the isolation of nucleic acids, a biological sample containing nucleic acids is suspended in a solution contai... | 11/09/1999 |
| 5983130 | Electrotransport agent delivery method and apparatus An electrotransport agent delivery device for delivering a therapeutic agent through a body surface, and a method for increasing agent delivery efficiency, is provided. The device includes a current controller which delivers a pulsating electrotransport c... | 11/09/1999 |