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| Number | Title | Issue Date |
| 5366972 | 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection Disclosed are novel 5,11-dihydro-6H-dipyrido[3,2-b; 2',3'-e][1,4]diazepines. These are useful in the prevention or treatment of HIV infection.... | 11/22/1994 |
| 5358954 | Benzimidazoline-2-oxo-1-carboxylic acid derivatives useful as 5-HT receptor antagonists Pharmacologically active benzimidazoline-2-oxo-1-carboxylic acid compounds which are useful for treating a human host suffering from anxiety.... | 10/25/1994 |
| 5354659 | Method for detecting pathological pregnancy A method for the detection of the presence of inflammation in a patient by measuring the amount of circulating intercellular adhesion molecule (cICAM-1) in a sample of one or more bodily fluids of the patient and then comparing the amount of cICAM-1 in th... | 10/11/1994 |
| 5347020 | Process for the preparation and purification of thermolabile compounds The invention relates to a new process for the preparation and purification of thermolabile compounds.... | 09/13/1994 |
| 5302693 | Process for preparing poly-D,L-lactide and the use thereof as a carrier for active substances The invention relates to a process for preparing poly-D,L-lactide and its use as a carrier for active substances.... | 04/12/1994 |
| 5302694 | Process for preparing polyesters based on hydroxycarboxylic acids The present invention relates to a method of producing polyesters based on hydroxycarboxylic acids, more particularly based on -hydroxycarboxylic acids.... | 04/12/1994 |
| 5292753 | Separation of enantiomers of cimaterol, (-)-cimaterol and the use thereof in pharmaceutical compositions and animal feeds The invention relates to the separation of enantiomers of cimaterol, (-)-cimaterol, the addition salts thereof and processes for preparing them and their use in pharmaceutical compositions and animal feeds.... | 03/08/1994 |
| 5270322 | Imidazo[1,2-a]pyridines, pharmaceutical compositions containing these compounds and processes for preparing them Imidazo[1,2-a]pyridines of the formula ##STR1## wherein Ra to Re are as defined herein, the enantiomers and the salts thereof, which are useful as angiotensin antagonists and for treating conditions treatable with angiotensin an... | 12/14/1993 |
| 5264573 | Process for preparing 2-chloro-1,7-dihydropurin-6-one and a process for its purification A process for the preparation of 2-chloro-1,7-dihydropurin-6-one which comprises the steps of: a) suspending 2-thioxanthine in concentrated hydrocloric acid, to produce a suspension; and b) contacting the suspension with chlorine, to produce 2-chloro-1,7-... | 11/23/1993 |
| 5248695 | Separation of enantiomers of cimaterol, (-)-cimaterol and the use thereof in animal feeds The invention relates to the separation of enantiomers, of cimaterol, (-)-cimaterol, the addition salts thereof and processes for preparing them and their use in pharmaceutical compositions and animal feeds.... | 09/28/1993 |
| 5232946 | Phenylethanolamines, their use as pharmaceuticals and as performance enhancers in animals The invention relates to new phenylethanolamines of general formula ##STR1## wherein A represents a straight-chained or branched alkylene group, B represents a bond, an alkylene group, a carbonyl or hydroxymethylene group, R1 represents a hydro... | 08/03/1993 |
| 5223511 | Benzimidazoline-2-oxo-1-carboxylic acid compounds useful as 5-HT receptor antagonists New pharmacologically active benzimidazoline-2-oxo-1-carboxylic acid derivatives which are 5-HT receptor antagonists useful as antiemetic agents and as gastric prokinetic agents of the following formula: ##STR1## wherein R is hydrogen, C1-6 alk... | 06/29/1993 |
| 5212321 | Process for the preparation of trimethylene carbonate A process for producing trimethylene carbonate wherein 1,3-propanediol is reacted with diethylcarbonate in the presence of zinc powder, zinc oxide, tin powder, tin halide or an organo-tin compound, at an elevated temperature.... | 05/18/1993 |
| 5175157 | Cyclic amine derivatives, pharmaceutical compositions containing these compounds and methods for preparing them Disclosed are new cyclic amine derivatives of the formula I ##STR1## wherein the substituents are defined in the specification. These compounds are useful as for treating sinus tachycardia.... | 12/29/1992 |
| 5175291 | Process for preparing 1,3-dipropyl-8-(3-oxocyclopentyl)-xanthine A process for preparing 1,3-dipropyl-8-(3-oxocyclopentyl)-xanthine.... | 12/29/1992 |
| 5164386 | R(-)3-quinuclidinol derivatives Pharmacologically active R(-) 3-quinuclidinol derivatives are described which are muscarinic receptor blocking agents useful for the treatment of gastrointestinal and respiratory tract disorders of the following formula (I) ##STR1## wherein R re... | 11/17/1992 |
| 5135929 | Feed additive for improving growth in agricultural animals By using -mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilization of ... | 08/04/1992 |
| 5135932 | 2-hydroxypropylamino-alkyl-benzimidazoly-5-yl derivatives and their use in the treatment of heart disease The invention relates to new 2-hydroxy-n-propylamines of the formula R1 --O--CH2 --CHOH--CH2 --NH--A--R2 (I) wherein R1, R2 and A are defined as in claim 1, the tautomers, enantiomers and acid add... | 08/04/1992 |
| 5120442 | Process for the simultaneous chemical and biological elimination of solid and liquid organic waste There is described a process for the simultaneous chemical and biological elimination of solid and liquid waste and apparatus for performing this process in the form of a loop reactor corresponding to FIG. 1 in conjunction with a specially designed nozzle... | 06/09/1992 |
| 5106851 | Benzofused-N-containing heterocycle derivatives Compounds of the formula (I) ##STR1## wherein R represents H or C1-6 alkyl; R1 and R2 represent H, halogen, C1-6 alkyl, C1-6 alkoxy, C1-6 alkythio, C1-6 alkoxycarbonyl, carboxyl,... | 04/21/1992 |
| 5087625 | Pyridodiazepines and their use in the prevention or treatment of HIV infection Disclosed are novel pyridodiazepines. These compounds, as well as certain known 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-ones are useful in the treatment of AIDS, ARC and related disorders associated with HIV infection.... | 02/11/1992 |
| 5056623 | Process for the controlled release of metered quantities of lubricant when coating pressing tools with lubricating liquids and suspensions and apparatus for carrying out the process The specification describes a new process and apparatus for the controlled release of metered quantities of lubricating liquids or suspensions for applying a coating of lubricant to mechanically stressed zones of pressing tools in tablet-making machines, ... | 10/15/1991 |
| 5049587 | Ophthalmic solution for intraocular pressure adjustment Disclosed are novel opthalmic solutions useful for the treatment of ocular hypertension and glaucoma. These contain mabuterol as a preferred active ingredient.... | 09/17/1991 |
| 5008273 | Amino acid derivatives and their pharmaceutical use Amino acid derivatives of general formula ##STR1## (the definitions of the various symbols being explained in the specification) are suitable for treating high blood pressure and for cardioprotection. The new compounds are prepared and used in the us... | 04/16/1991 |
| 4990222 | Process for the purification of thermolabile compounds by distillation The invention relates to a new process for the purification, by distillation, of thermolabile compounds wherein a thermolabile compound is introduced into a twin screw extruder which is heated, in at least one zone, to the boiling temperature of the compo... | 02/05/1991 |
| 4970208 | Feed additive for improving growth in agricultural animals By using -mimetics, particularly compounds of general formulae I to III and the compounds listed in Table I, as feed additives in fattening animals, it has surprisingly been possible to improve the daily weight gain, the utilization of fodder and t... | 11/13/1990 |
| 4954516 | Use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants The invention relates to the use of 1-benzyl-aminoalkyl-pyrrolidinones as antidepressants.... | 09/04/1990 |
| 4948812 | 1-phenoxy-3-amino-2-propanols use thereof Compounds of formula ##STR1## (the substituents R1, R2, R3, R4 and R5 are explained in the specification) may be prepared by conventional methods. Owing to their favorable activity profile the compoun... | 08/14/1990 |
| 4931436 | Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds New condensed diazepinones of general formula I are described ##STR1## wherein B represents one of the divalent groups ##STR2## and X1, X2, A, R1 to R10 and Z are defined as in the specification.... | 06/05/1990 |
| 4910215 | Pharmaceutical formulations designed to stimulate the release of somatotropic hormone The use of 2,6-dichlorophenyl compounds as active principles in pharmaceutical formulations designed to stimulate the secretion or release of somatotropic hormone in man and animals is described.... | 03/20/1990 |
| 4886812 | Tetrahydro-benzthiazoles, the preparation thereof and their use as intermediate products or as pharmaceuticals This invention relates to new tetrahydrobenzthiazoles of general formula ##STR1## wherein R1 represents a hydrogen atom, an alkyl group, an alkenyl or alkynyl group, an alkanoyl group, a phenyl alkyl or phenyl alkanoyl group, while the abo... | 12/12/1989 |
| 4886801 | Diazine-ethenylphenyl oxamic acids and esters and salts thereof Compounds of the formula ##STR1## wherein R1 is hydrogen or alkyl of 1 to 4 carbon atoms; R2 is hydrogen, methyl, hydroxyl, alkoxy of 1 to 4 carbon atoms, di(alkyl of 1 to 2 carbon atoms)amino-(alkoxy of 1 to 4 carbon atoms) or ... | 12/12/1989 |
| 4873236 | Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds There are described new condensed diazepinones of general formula ##STR1## wherein .circle.B represents one of the divalent groups ##STR2## and D represents the groups ##STR3## and X1, X2 represents a .dbd.CH-- grou... | 10/10/1989 |
