Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 7595329 | Benzimidazolone carboxylic acid derivatives This invention relates to compounds of the formula (I): wherein R1, R2, R3, A and m are each as described herein or a pharmaceutically acceptable salt or solvate thereof, and compositions co... | 09/29/2009 |
| 7589109 | Oxyindole derivatives This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: A, R1, R2, R3, R4 and R5 are each as described... | 09/15/2009 |
| 7517909 | Amino acids with affinity for the α2δ-protein This invention relates to certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. ... | 04/14/2009 |
| 7491835 | Prodrugs of amino acids with affinity for the α2δ-protein This invention relates to prodrugs of certain amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorde... | 02/17/2009 |
| 7439236 | Pharmaceutical composition for the treatment of CNS and other disorders The present invention relates to compounds of formula I The substituent designations are as disclosed. At least one of B, Q, D and E is nitrogen. The present invention also provides a method of treating disorders of the Centr... | 10/21/2008 |
| 7220867 | Solid-state form of celecoxib having enhanced bioavailability The selective cyclooxygenase-2 inhibitory drug celecoxib is provided in amorphous form. Also provided is a celecoxib drug substance wherein the celecoxib is present, in at least a detectable amount, as amorphous celecoxib. Also provided is a celecoxib-crystallizatio... | 05/22/2007 |
| 7220434 | Dual-release compositions of a cyclooxygenase-2 inhibitor Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility, for example celecoxib, in an immediate-release fraction and a controlled-release, slo... | 05/22/2007 |
| 7172769 | Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility in a therapeutically effective amount, wherein the drug is present in the form of soli... | 02/06/2007 |
| 7141678 | Synthesis of diaryl pyrazoles A process for the qualitative preparation of 3-haloalkyl-1H-pyrazoles suitable for efficient, high payload commercial application. ... | 11/28/2006 |
| 7135489 | Crystalline form of 4-[5-methyl-3-phenylisoxazol-4-yl] benzenesulfonamide A stable crystalline form of 4-[5-methyl-3-phenylisoxazol-4-yl]benzenesulfonamide is described. This crystal structure, designated Form B, is more stable, has favorable handling properties and is characterized by its melting point, x-ray and other physical character... | 11/14/2006 |
| 7012094 | Substituted furans and furanones for the treatment of inflammation A class of 3,4-diaryl substituted thiophene, furan and pyrrole derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are defin... | 03/14/2006 |
| 6964978 | Solid-state form of celecoxib having enhanced bioavailability The selective cyclooxygenase-2 inhibitory drug celecoxib is provided in amorphous form. Also provided is a celecoxib drug substance wherein the celecoxib is present, in at least a detectable amount, as amorphous celecoxib. Also provided is a celecoxib-crystallizatio... | 11/15/2005 |
| 6956052 | Substituted pyrazolyl compounds for the treatment of inflammation The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthri... | 10/18/2005 |
| 6864373 | Stable amorphous celecoxib composite and process therefor A process is provided for preparing a celecoxib-crystallization inhibitor composite wherein at least a detectable amount of celecoxib is in amorphous form. Also provided are compositions prepared according to such a process. Also provided is a method of treating a m... | 03/08/2005 |
| 6849653 | Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation The present invention relates to substituted pyrazolyl derivatives, compositions comprising such, intermediates, methods of making substituted pyrazolyl derivatives, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthri... | 02/01/2005 |
| 6809111 | Prodrugs of COX-2 inhibitors A compound of Formula (I), or a pharmaceutically-acceptable salt thereof, suitable for use in the treatment of a cyclooxygenase-2 mediated disease is provided. Also provided is a pharmaceutical composition comprising a... | 10/26/2004 |
