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Attorney: Fishman; Bella


Number of patents: 210
Last date: May 08, 2012

1            
NumberTitleIssue Date
8175369Multi-nucleated cell classification and micronuclei scoring
Methods and systems for counting nuclei for cells in a cell-containing sample are disclosed, such as carried out on a computer. The methods comprise: receiving a raw image of the cell-containing sample; transforming the raw image into a segmented image comprising on...
05/08/2012
8121881Project management method and system
The method and system for managing a project with multiple tasks and milestones by defining probabilities of key project events and assessing their performance risk. Each task of the project is described as a waveform propagating from this task to an assigned milest...
02/21/2012
8119066Multimode reader
A cartridge and cartridge system for use in an apparatus for analyzing a sample are provided. The cartridge has one or more light sources and/or optical systems and other components that are specific for a certain type of application such as fluorescence, absorbance...
02/21/2012
8048289Parallel patch clamp system
A system for high-throughput analysis of membranous samples having ion channels including at least one membranous sample, a multi-compartment structure including an extracellular chamber, an opposing intracellular chamber and a partition separating the extracellular...
11/01/2011
7855361Detection of positive and negative ions
An ion detector comprises an ion guide with electrodes arranged about a first axis; a positive ion detection device with an ion inlet at a first side of the ion output section offset from and at an angle to the first axis; and a negative ion detection device with an...
12/21/2010
7842918Chemical structure-insensitive method and apparatus for dissociating ions
In a method for exciting a precursor ion in an ion trap, the ion is trapped in a nonlinear trapping field that includes a quadrupolar field and a multipole field. The quadrupolar field is generated by applying a radio-frequency (RF) trapping voltage to the ion trap ...
11/30/2010
7817277Fiber optic probe and related apparatus, systems and methods for making optics-based measurements of liquid samples
A fiber-optic probe includes first and second optical fibers disposed in a body, a liquid sampling region between ends of the fibers and a reflector, and apertures communicating with the sampling region. The probe may be inserted in media in a vessel. Optical signal...
10/19/2010
7812606Demountable cryogenic NMR connection assembly systems and methods
In some embodiments, a NMR spectrometer includes a NMR probe circuit component (e.g. RF coil insert, capacitor, inductor) in thermal and electrical contact with a cryogenically-cooled NMR probe support through a collet assembly. The collet assembly includes a collet...
10/12/2010
7800369Hybrid automatic tuning/matching for NMR probes
Remote adjustment of a selected one of a plurality of adjustable NMR probe circuit components is achieved with a plurality of selectable linear actuators, the selected one of which urges a platen against a respective driven gear, azimuthally locked to its shaft, to ...
09/21/2010
7791339RF-switched superconducting resonators and methods of switching thereof
A multimode resonator resonating at two or more frequencies is operated at cryogenic temperatures and composed of a superconducting material or a normal metal with a superconducting section serving as a RF superconducting switch. The multimode resonator is coupled t...
09/07/2010
7779528Test gas leak detection using a composite membrane
A leak detector includes a leak detector inlet to receive a test gas; a vacuum pump coupled to the leak detector inlet; a test gas sensing unit connected through a passage to the leak detector inlet; and a membrane that is permeable to the test gas disposed in the p...
08/24/2010
7749772Antibody and immunoassays for determining the presence of Δ-Tetrahydrocannabinol
Antibodies having specific binding for the parent THC (Δ9-THC) and its major metabolites are provided which present a significant increase in sensitivity of immunoassays such as lateral flow immunoassays and ELISA for THC. The present invention also prov...
07/06/2010
7745781Real-time control of ion detection with extended dynamic range
In a method controlling an ion detector, one or more ion input signals are received at the ion detector. A data point indicative of an intensity of at least one of the received ion input signals is acquired. Asynchronously with acquiring the data point, a drive volt...
06/29/2010
7743790Shutter and gate valve assemblies for vacuum systems
A shutter and gate valve assembly includes a valve housing that defines a passage therethrough, a valve member having a valve aperture, the valve member movable between a non-operating position that seals the passage and an operating position that aligns the valve a...
06/29/2010
7701228Switchable manual/motor-driven NMR tuning systems and methods
According to some embodiments, motor-tuned nuclear magnetic resonance (NMR) probes may be tuned manually without overcoming the tuning motor holding force. An NMR probe includes a switchable manual-mode/motor-driven mode capacitance-adjustment assembly for adjusting...
04/20/2010
7701219Capacitor switches for NMR
NMR (Nuclear Magnetic Resonance) capacitor switches allow for adjusting the resonant frequency ranges of NMR measurement circuits by inserting or removing capacitors having different values into the circuits. A change of position of a single switching member is used...
04/20/2010
7701217NMR spiral RF probe coil pair with low external electric field
RF electric fields produced by electric potential differences in NMR probe coil windings may penetrate the NMR sample and sample tube causing sensitivity loss and noise in NMR spectroscopy. Counter-wound spiral coils placed on the opposite surfaces of a planar subst...
04/20/2010
7701123Electron source for ionization with leakage current suppression
An electron source includes a first electrode, a second electrode, a thermionic element interposed between and electrically isolated from the first electrode and the second electrode, and a guard electrode interposed between and electrically isolated from the first ...
04/20/2010
7651762Methods and devices using a shrinkable support for porous monolithic materials
Articles of manufacture and devices and methods of forming and using the same are provided, wherein the article comprises a porous inorganic substrate contained in or bounded by a support made from an inorganic material are provided, wherein said porous substrate an...
01/26/2010
7629868Cryogenic cooling of superconducting magnet systems below temperature of 4.2 K
A superconducting magnet system comprises a cryogenic vessel (1), a superconducting magnet (11) contained in an inner reservoir (16) within the vessel (1) to be cooled by liquid helium within the inner reservoir (16), and an outer ...
12/08/2009
7629575Charge control for ionic charge accumulation devices
A method for controlling charge flux into a charge accumulation device includes determining a charge accumulation time during which charges are to be accumulated in the charge accumulation device, measuring a charge flux of a first ion beam produced from an ion sour...
12/08/2009
7628915Metal cyano bonded phases
A composition for use in chromatography is provided comprising a substrate modified with a metal-cyano bonded phase. This novel cyano bonded phase provides superior performance in high performance liquid chromatography (HPLC) and provides superior selectivity, impro...
12/08/2009
7628577Vacuum pumps with improved pumping channel configurations
A vacuum pump includes a housing having an inlet port and an exhaust port, at least one molecular drag stage within the housing, the molecular drag stage including a rotor and a stator that defines a tangential flow channel which opens onto a surface of the rotor, a...
12/08/2009
7621721Vacuum pumping device with electronic control of the motor
An oil mechanical vacuum pump, which is equipped with an electric motor comprises an electronic control device for supplying the electric motor with power. The electronic control device comprises a frequency converter for controlling the excitation frequency Fe...
11/24/2009
7598738Complete structure elucidation of molecules utilizing single NMR experiment
The complete structure of a molecule of interest is determined from a single NMR experiment utilizing a single NMR pulse sequence. The experiment utilizes the same pulse sequence for acquiring various one-dimensional and multi-dimensional spectra, with independent r...
10/06/2009
7597013Device and method for detecting the presence of test gas
A device and a method provide a detection of a presence of a test gas. The device comprises a vacuum chamber connected to a vacuum pump equipped with an electronic power supply unit. At least one portion of the chamber is separated from a surrounding outside environ...
10/06/2009
7595641Electronic NMR reference signal systems and methods
According to some embodiments, a synthetic nuclear magnetic resonance (NMR) reference signal is injected into the receive path of an NMR spectrometer, after the NMR probe and before the receive amplifier. The synthetic signal is generated using a transmit path for t...
09/29/2009
7595026Solid phase extraction pipette
Solid phase extraction devices for sample preparation are disclosed, comprising a hollow conical tube having one narrower opening and one broader opening, wherein the narrower opening of the tube contains a solid phase extraction material comprising a functionalized...
09/29/2009
7588426Oil rotary vacuum pump and manufacturing method thereof
An oil rotary vacuum pump of mechanical type (100) is filled with a requested amount of oil at the end of the manufacturing process, then it is stored and then shipped to the user, letting the user to avoid an operation of introducing the proper amount of oil...
09/15/2009
7561268Evaporative light scattering detector
An improved evaporative light scattering detector apparatus for volatile samples is provided. Conventionally incomplete evaporation of the mobile phase (solvent) cannot be achieved for volatile samples as solvent cannot be fully removed at low temperature because th...
07/14/2009
7561266Calibrated spectroscopy instrument and method
A calibrated spectroscopy instrument and a method for calibrating a spectroscopy instrument are disclosed. The spectroscopy instrument includes a monochromator having a drive mechanism comprising a pair of spur gears for rotating a diffraction grating of the monochr...
07/14/2009
7560922Low temperature susceptibility compensation
The NMR device with a magnet utilizes a composition exhibiting a desired value of magnetic susceptibility, wherein the composition comprises a metal ion selected from the group consisting of Gd+3, Fe+3 and Mn+2 and an amorphous mater...
07/14/2009
7557578Low loss NMR sample holder
An elongate sample volume matching an elongate region of uniform RF magnetic field established by a saddle coil, is approximated by at least one pair of cylindrical sample tubes in parallel orientation with the geometric axis of the saddle coil. The displacement of ...
07/07/2009
7554660Plasma spectroscopy system with a gas supply
A spectroscopy system for spectro-chemical analysis of a sample includes a plasma torch (50) for generating a microwave induced plasma (90) as a spectroscopic source. The plasma forming gas is nitrogen which can contain an oxygen impurity. Thus the sys...
06/30/2009
7553123Annular support for rolling bearings
A support ring (1) for rolling bearings (11), especially for rolling bearings applied to rotors with very high rotation speed, such as rotors of rotary vacuum pumps, the ring comprising a pair of concentric cylindrical shells (3, 5) connected to...
06/30/2009
7547555Use of temperature and flow profiles in gradient elution based analytical process
A method and apparatus are provided for optimizing a liquid chromatography/mass spectrometry system for gradient elution. A temperature profile is determined according to which a gas is flowed into an atmospheric pressure ionization interface for vaporizing a matrix...
06/16/2009
7541807Rotor drive apparatus and methods utilizing center-fed radial-outflow gas
A rotor drive apparatus includes a rotor and a stator. The stator has a gas injection orifice located on the axis about which the rotor spins. The gas injection orifice communicates with a bearing gap formed between a tapered surface of the rotor and an axially spac...
06/02/2009
7540962Method of preparing spheroid polymer particles having a narrow size distribution by dispersion polymerization, particles obtainable by the method and use of these particles
The invention relates to a method of preparing spheroid polymer particles having a narrow size distribution by dispersion polymerization. This method comprises the steps of: providing a two-phase system in the form of a dispersion comprising an organic phase of drop...
06/02/2009
7512192Phase conjugated vectoring of signals in telephone cables
A phase conjugation vectoring (PCV) of signals propagating in telephone cables of twisted pairs provides crosstalk free transmission therethrough. The cable is considered a non-uniform physical media, and criteria for phase conjugation of electromagnetic fields are ...
03/31/2009
7501828Switchable birdcage coil
A switchable birdcage coil functioning as a transmitter coil and a separate RF surface coil functioning as the receiver coil are utilize in NMR and MRI apparatus. To prevent the switchable birdcage coil from absorbing energy by coupling to the receiver coil or by ab...
03/10/2009
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