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| Number | Title | Issue Date |
| 5770689 | Hepatitis E virus ORF Z peptides An antigen composition hepatitis E virus (HEV) infection are disclosed. The antigen composition includes peptides corresponding to carboxyl terminal end regions of the second and third open reading frames of the HEV genome.... | 06/23/1998 |
| 5693506 | Process for protein production in plants This invention provides for the secretion of heterologous protein in plant systems. In particular, this invention provides for the production of heterologous proteins in plant cultu1res and seeds. Where seeds are the source of the protein, the heterologou... | 12/02/1997 |
| 5643718 | Transfection and genetic manipulations in obligate intracellular parasites A method of transient transfection of obligate intracellular parasites is described. This method is exploited to develop a system for stable transformation utilizing selectable genes. For example, introduction of the chloramphenicol acetyl transferase (CA... | 07/01/1997 |
| 5538865 | Hepatitis C virus epitopes Peptide antigens which are immunoreactive with sera from individuals infected with hepatitis C virus (HCV) are disclosed. Several of the antigens are immunologically reactive with antibodies present in individuals identified as having chronic and acute HC... | 07/23/1996 |
| 5521063 | Polynucleotide reagent containing chiral subunits and methods of use The present invention describes an assay system wherein target polynucleotide molecules are captured on a support by base-specific binding to support-bound polymers, which are themselves substantially uncharged, and the target polynucleotides can be detec... | 05/28/1996 |
| 5506098 | In situ hybridization method A method of identifying the presence of a known target sequence in double-stranded DNA contained in a fixed cellular or subcellular biological structure. By adding a stable, reporter-labeled RecA/single-stranded probe complex to the structure, the target ... | 04/09/1996 |
| 5470974 | Uncharged polynucleotide-binding polymers A composition of polymer molecules effective to bind, with substantially uniform binding affinity, to a single-stranded polynucleotide containing a target sequence of bases. The polymer molecules are composed of a sequence of base-pairing moieties effecti... | 11/28/1995 |
| 5443965 | Hepatitis C virus epitopes Peptide antigens which are immunoreactive with sera from individuals infected with hepatitis C virus (HCV) are disclosed. Several of the antigens are immunologically reactive with antibodies present in individuals identified as having chronic and acute HC... | 08/22/1995 |
| 5436318 | Hepatitis C virus epitopes Peptide antigens which are immunoreactive with sera from individuals infected with hepatitis C virus (HCV) are disclosed. Several of the antigens are immunologically reactive with antibodies present in individuals identified as having chronic and acute HC... | 07/25/1995 |
| 5415874 | Natural killer cell lines and clones with antigen specificity Lymphocytes of NK phenotype were cultured with stimulator cell lines in the presence of growth factor containing medium. The resulting lines and clones derived from these lines expressed CD16 and/or Leu 19, but lacked detectable CD3 or T cell receptor γ/... | 05/16/1995 |
| 5378841 | Alpha-morpholino ribonucleoside derivatives and polymers thereof Alpha-morpholino subunits and polymer compositions composed of alpha-morpholino subunits are disclosed. These subunits can be linked together by uncharged linkages, one to three atoms in length, joining the morpholino nitrogen of one subunit to the 5' exo... | 01/03/1995 |
| 5283257 | Method of treating hyperproliferative vascular disease This invention provides a method of preventing or treating hyperproliferative vascular disease in a mammal by administering an amount of mycophenolic acid effective to inhibit intimal thickening.... | 02/01/1994 |
| 5264101 | Capillary electrophoresis molecular weight separation of biomolecules using a polymer-containing solution A capillary tube with a charged inner surface for use in capillary electrophoresis and methods. The tube is filled with an electrolyte solution containing 0.05-30% weight/weight of a hydrophilic polymer which is characterized by (A) a molecular weight of ... | 11/23/1993 |
| 5258289 | Method for the selecting of genes encoding catalytic antibodies The present invention describes methods of screening for or selecting a catalytic antibody effective to cleave a target peptide. In particular, in the selection method of the present invention a phage gene is selected that encodes a gene product necessary... | 11/02/1993 |
| 5142047 | Uncharged polynucleotide-binding polymers A composition of polymer molecules effective to bind, with substantially uniform binding affinity, to a single-stranded polynucleotide containing a target sequence of bases. The polymer molecules are composed of a sequence of base-pairing moieties effecti... | 08/25/1992 |
