Apparatus for Simulating a High Five
A self-righting hand-arm configuration which is adapted to pivot when struck by a user, thereby simulating a "high five."
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| Number | Title | Issue Date |
| 8445497 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 05/21/2013 |
| 8445490 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV... | 05/21/2013 |
| 8436000 | Substituted carbamate derivatives as modulators of corticotropin-releasing factor receptor activity The disclosure provides compounds of formula (I), including their salts, as well as compositions and methods of using the compounds. The compounds are CRF receptor antagonists and may be useful for treating disorders associated with abnormal CRF levels or aberrant f... | 05/07/2013 |
| 8431568 | Aromatic heterocyclic fused indolobenzadiazepine HCV NS5B inhibitors The disclosure provides compounds of formula (I), including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. | 04/30/2013 |
| 8383821 | NK-1 and serotonin transporter inhibitors The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating disorders associated with an excess or imbalance of tachykinins or serotonin or both. | 02/26/2013 |
| 8383639 | HIV integrase inhibitors The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also enco... | 02/26/2013 |
| 8372847 | Pyrazinone modulator of corticotropin-releasing factor receptor activity The invention relates to the compound (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile, pharmaceutical compositions of the compound, and methods of using the compound for the treatmen... | 02/12/2013 |
| 8354410 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 01/15/2013 |
| 8324212 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 12/04/2012 |
| 8314117 | CGRP receptor antagonists The disclosure generally relates to the novel compounds of formula I, including pharmaceutically acceptable salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of... | 11/20/2012 |
| 8309577 | Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervou... | 11/13/2012 |
| 8309558 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 11/13/2012 |
| 8293909 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. | 10/23/2012 |
| 8278320 | Azabicyclo[2.2.1]heptane compounds as alpha-7 nicotinic acetylcholine receptor ligands The disclosure provides compounds of formula I, including Ia, Ib, Ic, or Id, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various di... | 10/02/2012 |
| 8198449 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. | 06/12/2012 |
| 8178523 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula (I), including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 05/15/2012 |
| 8148382 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 04/03/2012 |
| 8143403 | CGRP receptor antagonists The disclosure generally relates to the novel compounds of formula I, including their salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of CGRP related disorder... | 03/27/2012 |
| 8143244 | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 03/27/2012 |
| 8143243 | Compounds for the treatment of hepatitis C The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. ... | 03/27/2012 |
| 8138171 | Dioxolane and dioxolanone fused indolobenzadiazepine HCV NS5B inhibitors The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. I. ... | 03/20/2012 |
| 8133884 | Compounds for the treatment of hepatitis C The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. ... | 03/13/2012 |
| 8129398 | HIV integrase inhibitors The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also enco... | 03/06/2012 |
| 8129367 | Compounds for the treatment of Hepatitis C The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. ... | 03/06/2012 |
| 8124601 | Compounds for the treatment of Hepatitis C The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. ... | 02/28/2012 |
| 8119629 | Carboxamide GABAα2 modulators The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders. ... | 02/21/2012 |
| 8119628 | Pyrrolidine fused indolobenzadiazepine HCV NS5B inhibitors The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. | 02/21/2012 |
| 8071778 | Substituted heterocyclic ethers and their use in CNS disorders The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders. ... | 12/06/2011 |
| 8048887 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 11/01/2011 |
| 8044043 | CGRP receptor antagonists The disclosure generally relates to the novel compounds of formula I, including their salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of CGRP related disorder... | 10/25/2011 |
| 8039458 | HIV integrase inhibitors The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharm... | 10/18/2011 |
| 8026257 | Substituted heterocyclic ethers and their use in CNS disorders The invention encompasses compounds of Formula I, including pharmaceutically acceptable salts, their pharmaceutical compositions, and their use in treating CNS disorders. ... | 09/27/2011 |
| 7998951 | HCV NS5B inhibitors The invention encompasses compounds of Formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. ... | 08/16/2011 |
| 7994171 | Compounds for the treatment of hepatitis C The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV. ... | 08/09/2011 |
| 7968555 | Intermediates in the preparation of entecavir via carbon-silicon oxidation Processes for preparing entecavir and novel intermediates thereof using carbon-silicon oxidation. ... | 06/28/2011 |
| 7968541 | Crystalline form of N-[[4-fluoro-2-(5-methyl-1H-1,2,4-triazol-1-yl)phenyl]methyl]-4,6,7,9-tetrahydro-3-hydroxy-9,9-dimethyl-4-oxo-pyrimido[2,1-C][1,4]-oxazine-2-carboxamide, sodium salt monohydrate Disclosed is a crystalline form of N-[[4-fluoro-2-(5-methyl-1H-1,2,4-triazol-1-yl)phenyl]methyl]-4,6,7,9-tetrahydro-3-hydroxy-9,9-dimethyl-4-oxo-pyrimido[2,1-c][1,4]oxazine-2-carboxamide, sodium salt monohydrate. Also disclosed are at least one pharmaceutical compos... | 06/28/2011 |
| 7932256 | ()-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile: a pyrazinone modulator of corticotropin-releasing factor receptor activity The invention relates to the compound (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-(6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile, pharmaceutical compositions of the compound, and methods of using the compound for the treatmen... | 04/26/2011 |
| 7902182 | HIV integrase inhibitors The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharm... | 03/08/2011 |
| 7897593 | HIV integrase inhibitors The invention encompasses series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmac... | 03/01/2011 |
| 7897592 | HIV integrase inhibitors The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharm... | 03/01/2011 |