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| Number | Title | Issue Date |
| 7887896 | Fabric fillet A fillet is disclosed for enhancing the appearance of a frame or mat and comprises a flexible material, an elastomeric cord and an adhesive securing the fabric to the cord. The flexible material may have one or more flairs which may have a tape adhesive which adhere... | 02/15/2011 |
| 7842791 | Dispersible pharmaceutical compositions A pharmaceutical composition is provided comprising a vehicle that comprises (a) an amphipathic oil that is water dispersible and ethanol insoluble, (b) microcrystalline wax, and (c) a pharmaceutically acceptable non-aqueous carrier; and having an antibacterial subs... | 11/30/2010 |
| 7829100 | Pharmaceutical composition having modified carrier A composition comprising: (a) one to three bioactive agents; and (b) a modified liquid vehicle; wherein immediately after manufacture of the composition, said composition can be administered to a host such that the one to three bi... | 11/09/2010 |
| 7659061 | Pharmaceutical compositions having a modified vehicle A composition comprising: (a) one to three bioactive agents; and (b) a vehicle comprising; (i) a modified liquid carrier, and (ii) an unmodified liquid carrier ... | 02/09/2010 |
| 7642350 | Purine derivatives This invention relates to purine derivatives, to processes for their preparation, to compositions containing them and to their use. The present invention provides compounds of formula (I) whe... | 01/05/2010 |
| 7638537 | Pyrazole compounds as transforming growth factor (TGF) inhibitors Novel pyrazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of transforming gro... | 12/29/2009 |
| 7462634 | N-(pyridin-2-yl)-sulfonamide derivatives The present invention relates to novel compounds, to pharmaceutical compositions comprising the compounds described herein, their pharmaceutically acceptable salts, hydrates and solvates, as well as to the use of the compounds in medicine and for the preparation of ... | 12/09/2008 |
| 7417041 | Imidazopyrimidines as transforming growth factor (TGF) inhibitors Novel fused heteroaromatic compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of tran... | 08/26/2008 |
| 7378436 | Compounds A compound of Formula (I) and pharmaceutically and/or veterinarily acceptable derivatives thereof, wherein R1 is H, C1-6alkyl, —C(X)Y, C3-8cycloalkyl, aryl, het, aryl-C1-4alkyl ... | 05/27/2008 |
| 7378408 | Methods of treatment and formulations of cephalosporin Formulations containing an antibacterial alkali metal salt of a cephalosporin compound and methods of treating bacterial infections in dogs and cats. ... | 05/27/2008 |
| 7355040 | Process for the preparation of cephalosporin compounds and synthetic intermediates There is provided a process for the preparation of a compound according to Formula (II): which includes the step of cyclizing a compound of Formula (III): wherein R1, R... | 04/08/2008 |
| 7351687 | Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated antibiotic 107891 which is produced by fermentation of Microbispora sp. ATCC PTA-5024, the pharmaceutically acceptable salts and compositions thereof, and their use ... | 04/01/2008 |
| 7335689 | Dihydroxyl compounds and compositions for cholesterol management and related uses The present invention relates to novel dihydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascula... | 02/26/2008 |
| 7319088 | Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated antibiotic 107891 which is produced by fermentation of Microbispora sp. ATCC PTA-5024, the pharmaceutically acceptable salts and compositions thereof, and their use ... | 01/15/2008 |
| 7307057 | Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated antibiotic 107891 which is produced by fermentation of Microbispora sp. ATCC PTA-5024, the pharmaceutically acceptable salts and compositions thereof, and their use ... | 12/11/2007 |
| 7304093 | Ketone compounds and compositions for cholesterol management and related uses The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a com... | 12/04/2007 |
| 7220770 | Heterocyclo-substituted imidazoles for the treatment of inflammation A class of imidazolyl compounds is described for use in treating inflammation. Compounds of particular interest are defined by formula (V), wherein R3 is a radical selected from hydrido, alkyl, haloalkyl, aralkyl, heterocycloalkyl, heteroaralkyl, acyl, cy... | 05/22/2007 |
| 7067670 | Sulfamato hydroxamic acid metalloprotease inhibitor A sulfamato hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a process for preparing the same, intermediate compounds useful in those syntheses, and a treatment process that comprises administering a contemplated ... | 06/27/2006 |
| 6972286 | Oxazolidinones having a benzannulated 6- or 7-membered heterocycle The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents. ... | 12/06/2005 |
| 6960662 | Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones The present invention relates to a process for preparing 2-(pyridin-4-ylamino-pyrido [2,3-d]pyrimidine of Formula II by reacting a 4-aminopyridine of the formula with a 2... | 11/01/2005 |
| 6875784 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives The present invention provides certain [3.1.0] bicyclic oxazolidinone derivatives of Formulea I and II, described herein, or pharmaceutically acceptable salts or prodrugs thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for... | 04/05/2005 |
| 6870070 | Process to prepare 2-aminoindan derivatives The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: and a novel process for the preparation of them. ... | 03/22/2005 |
| 6861521 | Stereoselective transacetalization of steroidal C-22 acetonide The present invention is a process for the preparation of rofleponide of formula (II) where the 22R/22S ratio is 90/10 or greater which comprises contacting an acetonide of formula (I) | 03/01/2005 |
| 6852733 | Sodium-hydrogen exchanger type 1 inhibitor NHE-1 inhibitor, methods of using the NHE-1 inhibitor and pharmaceutical compositions containing the NHE-1 inhibitor. The NHE-1 inhibitor is useful for the reduction of tissue damage resulting from tissue ischemia. ... | 02/08/2005 |
| 6847840 | System and method for statistical analysis of QT interval as a function of changes in RR interval A system and method for statistically analyzing QT interval as a function of changes in the RR interval. The system and method utilize three statistical comparisons to fully characterize the QT response: (1) the comparison of curves to give an overall effect; (2) th... | 01/25/2005 |
| 6828120 | Process to prepare 11β, 17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate The present invention is a novel process for the transformation of 17α-hydroxy-6α-methylpregn-4-ene-3,20-dione 17-acetate (I) to 11β,17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate (VI) | 12/07/2004 |
| 6825225 | Bicyclic isoxazolinones as antibacterial agents The present invention provides compounds of formula I useful as anti microbial agents wherein X, Y, R1, and n are as defined in thereof. ... | 11/30/2004 |
| 6740754 | Process to produce oxazolidinones The present invention includes a number of novel intermediates such as the (S)-secondary alcohol of formula (VIIIA) X2—CH2—C*H(OH)—CH2—NH—CO—RN (VIIIA) and processes for pro... | 05/25/2004 |
| 6716980 | Process to produce oxazolidinones The present invention includes a number of novel intermediates such as the (S)-secondary alcohol of formula (VIIIA) X2—CH2—C•H(OH)—CH2—NH—CO—RN (VIIIA) and pr... | 04/06/2004 |
| 6689901 | Process and intermediates to prepare latanoprost The present invention is a novel intermediate, compound of the formula (VI) ##STR1## and salts thereof. In addition, the invention includes a process for the preparation of a 15(S)-prostaglandin intermediates compounds (IV) and (XVIII) which comprises (1)... | 02/10/2004 |
| 6613944 | Process to produce 3-carbon amino alcohol salts The present invention includes a number of novel intermediates such as the (S)-secondary alcohol of formula (VIIIA) and processes for production of pharmacologically useful oxazolidinones.... | 09/02/2003 |
| 6586595 | Process to prepare (5R)-(methylamino)-5, 6-dihydro-4H-imidazo[4,5,1-ij]-quinolin-2(1H)-one The present invention is an improved prosess to prepare (5R)-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one the compound of formula (VII)... | 07/01/2003 |
| 6563003 | Process to produce amino alcohol salts The present invention includes a number of novel intermediates such as the (S)-secondary alcohol of formula (VIIIA) X2 --CH2 --C*H(OH)--CH2 --NH--CO--RN (VIIIA) and processes for production of pharmacologically useful ox... | 05/13/2003 |
| 6559305 | Linezolid--crystal form II The invention is a novel crystal form (Form II) of a known compound, linezolid ##STR1## which is useful as an antibacterial agent.... | 05/06/2003 |
| 6514968 | Aminoalkoxy carbazoles for the treatment of cns diseases The present invention provides aminoalkoxy carbazole derivatives, and more specifically, provides compounds of formula (I) ##STR1## wherein R1, R2, R3, R4, R8 and R9 are described herein. T... | 02/04/2003 |
| 6180679 | Method for treating fungal infections The present invention provides a method for controlling fungal growth, mycotic infections, yeast infections and parasitic infections using a therapeutically effective amount of a compound selected from Compounds (I-V). Further provided is a method for pro... | 01/30/2001 |
| 6143909 | Selective epoxidation process for preparing pharmaceutical compounds Cryptophycin compounds possessing a ଲ-epoxy moiety may be made with high stereoselectivity at various steps in the overall synthetic process. This invention also provides novel intermediates useful in preparing Cryptophycin compounds.... | 11/07/2000 |
| 6103913 | Process for preparing enollactone derivatives This invention provides processes for preparing lactone intermediates useful for the preparation of pharmaceutical compounds such as tetrahydrolipstatin and cryptophycin compounds.... | 08/15/2000 |
| 6026817 | Method of treating the syndrome of coronary heart disease risk factors in humans A method of treatment of humans suffering from the Coronary Heart Disease Risk Factor (CHDRF) Syndrome which comprises the steps of 1) administering, by a pharmaceutically effective mode, a priming dose of drug composition selected from the group consisti... | 02/22/2000 |
| 5878750 | Method of treating the syndrome of coronary heart disease risk factors in humans A method of treatment of humans suffering from the Coronary Heart Disease Risk Factor (CHDRF) Syndrome which comprises administering, by a pharmaceutically effective mode, a drug composition selected from the group consisting of opiate antagonists or anti... | 03/09/1999 |
