U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

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...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.

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Attorney: Engellenner; Thomas J.


Number of patents: 393
Last date: May 15, 2012

1                    
NumberTitleIssue Date
8177789Distraction osteogenesis methods and devices
Methods and devices for distraction osteogenesis are disclosed employing an energy storage device and a controlled release of energy to provide a separating force. For example, bone expansion devices can include a first anchor element attachable to a first segment o...
05/15/2012
8173523Method of removing heavy metal in semiconductor substrate
To provide a method of removing a heavy metal contained in a thinned semiconductor substrate. A method of removing a heavy metal in a semiconductor substrate of the present invention comprises: attaching, to a rear surface of the semiconductor substrate, a ma...
05/08/2012
8168879Solar thermoelectric conversion
Systems and methods utilizing solar-electrical generators are discussed. Solar-electrical generators are disclosed having a radiation-capture structure and one or more thermoelectric converters. Heat produced in a capture structure via impingement of solar radiation...
05/01/2012
8158338Resist sensitizer
Methods and compositions for enhancing the sensitivity of a resist composition are disclosed. In one aspect, compositions for use with a matrix material (e.g., a lithographically sensitive polymeric material) can be formulated with an acid generator and a sensitizer...
04/17/2012
8153370RNA from cytology samples to diagnose disease
The invention relates to methods and kits for detecting the likelihood that a subject has cancer, e.g., squamous cell carcinoma, by assaying the expression levels of tumor associated genes. More specifically, the expression levels of nucleic acids or proteins can be...
04/10/2012
8143686Laser-induced structuring of substrate surfaces
In one aspect, the present invention provides a method of processing a substrate, e.g., a semiconductor substrate, by irradiating a surface of the substrate (or at least a portion of the surface) with a first set of polarized short laser pulses while exposing the su...
03/27/2012
D656620Light-based treatment device
03/27/2012
8116223System and method for supporting automatic establishing and disconnecting several wireless connections
A method for automatically establishing wireless connections between a plurality of grouped wireless devices and a third party wireless device, comprising the steps of: forming a connection group having a first wireless device and at least one additional grouped wir...
02/14/2012
8110339Multi-tone resist compositions
Multi-tone resists can enhance the resolution limit of a lithographic process by advantageously using the changeable solubility of a resist composition as a function of lithographic radiation dosage. By imaging a multi-tone resist with different doses of lithographi...
02/07/2012
8109924Heads for dermatology treatment
Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, var...
02/07/2012
8080467Silicon-based visible and near-infrared optoelectric devices
In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction w...
12/20/2011
8014959Population of background suppression lists from limited data in agent detection systems
Methods and systems are disclosed for detection of agents such as pathogens or toxic substances and, in particular, to methods and systems for determining the most important background constituents to suppress in a sample, e.g., in a bulk aerosol sample, in order to...
09/06/2011
8003551Surface-activation of semiconductor nanostructures for biological applications
The present invention provides means and methods for producing surface-activated semiconductor nanoparticles suitable for in vitro and in vivo applications that can fluoresce in response to light excitation. Semiconductor nanostructures can be produced by generating...
08/23/2011
8002768Light energy delivery head
A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is apply...
08/23/2011
8000220Digital data transmitting apparatus and digital data receiving apparatus
To provide a digital data transmitting apparatus and a digital data receiving apparatus that can realize, even when a transmission channel characteristic changes because of aged deterioration or the like of a relay, improvement of a reception performance following t...
08/16/2011
7955855Detection of materials via nitrogen oxide
Methods and devices for detecting the presence of a NO forming material (e.g., a material that can form, or is, a nitrogen monoxide molecule) are disclosed based on detection of fluorescence exhibited by NO molecules in a first vibrationally excited state of a groun...
06/07/2011
7942916Phototreatment device for use with coolants and topical substances
Methods and systems are disclosed for phototreatment in which replaceable containers comprising one or more adjuvant (consumable or re-useable) substances are employed. The adjuvant substance can be, for example, a topical substance or a coolant. Systems are disclos...
05/17/2011
7942915Phototreatment device for use with coolants
Methods and systems are disclosed for phototreatment in which replaceable containers comprising one or more adjuvant (consumable or re-useable) substances are employed. The adjuvant substance can be, for example, a topical substance or a coolant. Systems are disclos...
05/17/2011
7935333Method and compositions for modifying target receptor function associated with neurological disorders
A method of treating or preventing development of a neurological disorder has been developed wherein a subject with the disorder, or at risk of developing a disorder, is vaccinated against a brain protein or antigen. Alternatively, the antibodies can be directly adm...
05/03/2011
7935107Heads for dermatology treatment
Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, var...
05/03/2011
7902723Screw thread driving polyhedral ultrasonic motor
A screw thread driving polyhedral ultrasonic motor includes a stator, a rotor and multiple piezoelectric plates being bonded to the stator or the rotor. The stator and the rotor have screw threads matched with each other. The stator and the rotor are connected via t...
03/08/2011
7902185Treatment of neurodegenerative diseases using proteasome modulators
Methods for modulating proteasome activity in a subject is provided. Proteasome activity is modulated by administering a therapeutically effective amount of proteasome modulating pharmacological agent to a subject. In a preferred embodiment, the proteasome modulatin...
03/08/2011
7884446Femtosecond laser-induced formation of submicrometer spikes on a semiconductor substrate
The present invention generally provides semiconductor substrates having submicron-sized surface features generated by irradiating the surface with ultra short laser pulses. In one aspect, a method of processing a semiconductor substrate is disclosed that includes p...
02/08/2011
7884439Silicon-based visible and near-infrared optoelectric devices
In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction w...
02/08/2011
7864312Substrates for Raman spectroscopy having discontinuous metal coatings
In one aspect, the present invention provides methods for fabricating substrates for use in a variety of analytical and/or diagnostic applications. Such a substrate can be generated by exposing a semiconductor surface (e.g., silicon surface) to a plurality of short ...
01/04/2011
7844224Method for supporting simultaneously multiple-path Bluetooth audio applications
An optimized method for supporting simultaneously multipath Bluetooth audio application in a system includes said system establishes Bluetooth audio connections with a plurality of remote Bluetooth device simultaneously said system selects or adds dedicated Bluetoot...
11/30/2010
7829281Compositions and methods for obesity screening using polymorphisms in NPY2R
Methods and constructs are provided that are predictive of a subject's susceptibility to developing a metabolic disorder, such as obesity. The disclosed naturally-occurring SNPs located upstream of the NPY2R gene can be used as targets for the design of diagnostic r...
11/09/2010
7816220Laser-induced structuring of substrate surfaces
In one aspect, the present invention provides a method of processing a substrate, e.g., a semiconductor substrate, by irradiating a surface of the substrate (or at least a portion of the surface) with a first set of polarized short laser pulses while exposing the su...
10/19/2010
7807408Directed evolution of proteins
Disclosed is a method of altering a nucleic acid such as RNA or DNA. The method comprises fragmenting a parent nucleic acid strand to generate nucleic acid fragments. At least a subset of the fragments are ligated to generate shuffled nucleic acid strands. A selecte...
10/05/2010
7781856Silicon-based visible and near-infrared optoelectric devices
In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction w...
08/24/2010
7772612Nanophotovoltaic devices
The present invention provides nanophotovoltaic devices having sizes in a range of about 50 nm to about 5 microns, and method of their fabrication. In some embodiments, the nanophotovoltaic device includes a semiconductor core, e.g., formed of silicon, sandwiched be...
08/10/2010
7771773Nano-crystalline, homo-metallic, protective coatings
The present invention provides orthopedic prosthesis having at least one metallic component that includes a metallic substrate on which an integrally formed nano-crystalline coating is formed. The coating and the substrate have at least one metallic constituent in c...
08/10/2010
7763016Light energy delivery head
A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is apply...
07/27/2010
7759257Precision synthesis of quantum dot nanostructures for fluorescent and optoelectronic devices
Methods are disclosed generally directed to design and synthesis of quantum dot nanoparticles having improved uniformity and size. In a preferred embodiment, a release layer is deposited on a semiconductor wafer. A heterostructure is grown on the release layer using...
07/20/2010
7758621Method and apparatus for therapeutic EMR treatment on the skin
Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, var...
07/20/2010
7745102Immersion fluids for lithography
Compositions for use as immersion fluids are described. In general, the immersion fluids can be utilized to perform lithography at short wavelengths (e.g., in a range from about 120 nm to about 260 nm). Some embodiments can be used in a range of actinic radiation be...
06/29/2010
7720204Method of establishing a communications call
A method system, interface and server for establishing a communications call by selecting a B party (6) using an interactive device (16) connected to a public network (10,12), sending called address data for the B party (6) and calling ad...
05/18/2010
7715003Metalized semiconductor substrates for raman spectroscopy
In one aspect, the present invention generally provides methods for fabricating substrates for use in a variety of analytical and/or diagnostic applications. Such a substrate can be generated by exposing a semiconductor surface (e.g., silicon surface) to a plurality...
05/11/2010
7713981Method and compounds for inhibition of cell death
The invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for identifying other inhibitors of Omi/HtrA2. Also disclosed are Omi/Htr...
05/11/2010
7692147Real-time, continuous-wave terahertz imaging using a microbolometer focal-plane array
The present invention generally provides a terahertz (THz) imaging system that includes a source for generating radiation (e.g., a quantum cascade laser) having one or more frequencies in a range of about 0.1 THz to about 10 THz, and a two-dimensional detector array...
04/06/2010
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