...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 8177789 | Distraction osteogenesis methods and devices Methods and devices for distraction osteogenesis are disclosed employing an energy storage device and a controlled release of energy to provide a separating force. For example, bone expansion devices can include a first anchor element attachable to a first segment o... | 05/15/2012 |
| 8173523 | Method of removing heavy metal in semiconductor substrate To provide a method of removing a heavy metal contained in a thinned semiconductor substrate. A method of removing a heavy metal in a semiconductor substrate of the present invention comprises: attaching, to a rear surface of the semiconductor substrate, a ma... | 05/08/2012 |
| 8168879 | Solar thermoelectric conversion Systems and methods utilizing solar-electrical generators are discussed. Solar-electrical generators are disclosed having a radiation-capture structure and one or more thermoelectric converters. Heat produced in a capture structure via impingement of solar radiation... | 05/01/2012 |
| 8158338 | Resist sensitizer Methods and compositions for enhancing the sensitivity of a resist composition are disclosed. In one aspect, compositions for use with a matrix material (e.g., a lithographically sensitive polymeric material) can be formulated with an acid generator and a sensitizer... | 04/17/2012 |
| 8153370 | RNA from cytology samples to diagnose disease The invention relates to methods and kits for detecting the likelihood that a subject has cancer, e.g., squamous cell carcinoma, by assaying the expression levels of tumor associated genes. More specifically, the expression levels of nucleic acids or proteins can be... | 04/10/2012 |
| 8143686 | Laser-induced structuring of substrate surfaces In one aspect, the present invention provides a method of processing a substrate, e.g., a semiconductor substrate, by irradiating a surface of the substrate (or at least a portion of the surface) with a first set of polarized short laser pulses while exposing the su... | 03/27/2012 |
| D656620 | Light-based treatment device | 03/27/2012 |
| 8116223 | System and method for supporting automatic establishing and disconnecting several wireless connections A method for automatically establishing wireless connections between a plurality of grouped wireless devices and a third party wireless device, comprising the steps of: forming a connection group having a first wireless device and at least one additional grouped wir... | 02/14/2012 |
| 8110339 | Multi-tone resist compositions Multi-tone resists can enhance the resolution limit of a lithographic process by advantageously using the changeable solubility of a resist composition as a function of lithographic radiation dosage. By imaging a multi-tone resist with different doses of lithographi... | 02/07/2012 |
| 8109924 | Heads for dermatology treatment Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, var... | 02/07/2012 |
| 8080467 | Silicon-based visible and near-infrared optoelectric devices In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction w... | 12/20/2011 |
| 8014959 | Population of background suppression lists from limited data in agent detection systems Methods and systems are disclosed for detection of agents such as pathogens or toxic substances and, in particular, to methods and systems for determining the most important background constituents to suppress in a sample, e.g., in a bulk aerosol sample, in order to... | 09/06/2011 |
| 8003551 | Surface-activation of semiconductor nanostructures for biological applications The present invention provides means and methods for producing surface-activated semiconductor nanoparticles suitable for in vitro and in vivo applications that can fluoresce in response to light excitation. Semiconductor nanostructures can be produced by generating... | 08/23/2011 |
| 8002768 | Light energy delivery head A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is apply... | 08/23/2011 |
| 8000220 | Digital data transmitting apparatus and digital data receiving apparatus To provide a digital data transmitting apparatus and a digital data receiving apparatus that can realize, even when a transmission channel characteristic changes because of aged deterioration or the like of a relay, improvement of a reception performance following t... | 08/16/2011 |
| 7955855 | Detection of materials via nitrogen oxide Methods and devices for detecting the presence of a NO forming material (e.g., a material that can form, or is, a nitrogen monoxide molecule) are disclosed based on detection of fluorescence exhibited by NO molecules in a first vibrationally excited state of a groun... | 06/07/2011 |
| 7942916 | Phototreatment device for use with coolants and topical substances Methods and systems are disclosed for phototreatment in which replaceable containers comprising one or more adjuvant (consumable or re-useable) substances are employed. The adjuvant substance can be, for example, a topical substance or a coolant. Systems are disclos... | 05/17/2011 |
| 7942915 | Phototreatment device for use with coolants Methods and systems are disclosed for phototreatment in which replaceable containers comprising one or more adjuvant (consumable or re-useable) substances are employed. The adjuvant substance can be, for example, a topical substance or a coolant. Systems are disclos... | 05/17/2011 |
| 7935333 | Method and compositions for modifying target receptor function associated with neurological disorders A method of treating or preventing development of a neurological disorder has been developed wherein a subject with the disorder, or at risk of developing a disorder, is vaccinated against a brain protein or antigen. Alternatively, the antibodies can be directly adm... | 05/03/2011 |
| 7935107 | Heads for dermatology treatment Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, var... | 05/03/2011 |
| 7902723 | Screw thread driving polyhedral ultrasonic motor A screw thread driving polyhedral ultrasonic motor includes a stator, a rotor and multiple piezoelectric plates being bonded to the stator or the rotor. The stator and the rotor have screw threads matched with each other. The stator and the rotor are connected via t... | 03/08/2011 |
| 7902185 | Treatment of neurodegenerative diseases using proteasome modulators Methods for modulating proteasome activity in a subject is provided. Proteasome activity is modulated by administering a therapeutically effective amount of proteasome modulating pharmacological agent to a subject. In a preferred embodiment, the proteasome modulatin... | 03/08/2011 |
| 7884446 | Femtosecond laser-induced formation of submicrometer spikes on a semiconductor substrate The present invention generally provides semiconductor substrates having submicron-sized surface features generated by irradiating the surface with ultra short laser pulses. In one aspect, a method of processing a semiconductor substrate is disclosed that includes p... | 02/08/2011 |
| 7884439 | Silicon-based visible and near-infrared optoelectric devices In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction w... | 02/08/2011 |
| 7864312 | Substrates for Raman spectroscopy having discontinuous metal coatings In one aspect, the present invention provides methods for fabricating substrates for use in a variety of analytical and/or diagnostic applications. Such a substrate can be generated by exposing a semiconductor surface (e.g., silicon surface) to a plurality of short ... | 01/04/2011 |
| 7844224 | Method for supporting simultaneously multiple-path Bluetooth audio applications An optimized method for supporting simultaneously multipath Bluetooth audio application in a system includes said system establishes Bluetooth audio connections with a plurality of remote Bluetooth device simultaneously said system selects or adds dedicated Bluetoot... | 11/30/2010 |
| 7829281 | Compositions and methods for obesity screening using polymorphisms in NPY2R Methods and constructs are provided that are predictive of a subject's susceptibility to developing a metabolic disorder, such as obesity. The disclosed naturally-occurring SNPs located upstream of the NPY2R gene can be used as targets for the design of diagnostic r... | 11/09/2010 |
| 7816220 | Laser-induced structuring of substrate surfaces In one aspect, the present invention provides a method of processing a substrate, e.g., a semiconductor substrate, by irradiating a surface of the substrate (or at least a portion of the surface) with a first set of polarized short laser pulses while exposing the su... | 10/19/2010 |
| 7807408 | Directed evolution of proteins Disclosed is a method of altering a nucleic acid such as RNA or DNA. The method comprises fragmenting a parent nucleic acid strand to generate nucleic acid fragments. At least a subset of the fragments are ligated to generate shuffled nucleic acid strands. A selecte... | 10/05/2010 |
| 7781856 | Silicon-based visible and near-infrared optoelectric devices In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction w... | 08/24/2010 |
| 7772612 | Nanophotovoltaic devices The present invention provides nanophotovoltaic devices having sizes in a range of about 50 nm to about 5 microns, and method of their fabrication. In some embodiments, the nanophotovoltaic device includes a semiconductor core, e.g., formed of silicon, sandwiched be... | 08/10/2010 |
| 7771773 | Nano-crystalline, homo-metallic, protective coatings The present invention provides orthopedic prosthesis having at least one metallic component that includes a metallic substrate on which an integrally formed nano-crystalline coating is formed. The coating and the substrate have at least one metallic constituent in c... | 08/10/2010 |
| 7763016 | Light energy delivery head A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is apply... | 07/27/2010 |
| 7759257 | Precision synthesis of quantum dot nanostructures for fluorescent and optoelectronic devices Methods are disclosed generally directed to design and synthesis of quantum dot nanoparticles having improved uniformity and size. In a preferred embodiment, a release layer is deposited on a semiconductor wafer. A heterostructure is grown on the release layer using... | 07/20/2010 |
| 7758621 | Method and apparatus for therapeutic EMR treatment on the skin Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, var... | 07/20/2010 |
| 7745102 | Immersion fluids for lithography Compositions for use as immersion fluids are described. In general, the immersion fluids can be utilized to perform lithography at short wavelengths (e.g., in a range from about 120 nm to about 260 nm). Some embodiments can be used in a range of actinic radiation be... | 06/29/2010 |
| 7720204 | Method of establishing a communications call A method system, interface and server for establishing a communications call by selecting a B party (6) using an interactive device (16) connected to a public network (10,12), sending called address data for the B party (6) and calling ad... | 05/18/2010 |
| 7715003 | Metalized semiconductor substrates for raman spectroscopy In one aspect, the present invention generally provides methods for fabricating substrates for use in a variety of analytical and/or diagnostic applications. Such a substrate can be generated by exposing a semiconductor surface (e.g., silicon surface) to a plurality... | 05/11/2010 |
| 7713981 | Method and compounds for inhibition of cell death The invention is directed to methods and compositions for inhibiting caspase-independent apoptosis. In particular, methods and compositions for inhibiting Omi/HtrA2 activity, as well as method for identifying other inhibitors of Omi/HtrA2. Also disclosed are Omi/Htr... | 05/11/2010 |
| 7692147 | Real-time, continuous-wave terahertz imaging using a microbolometer focal-plane array The present invention generally provides a terahertz (THz) imaging system that includes a source for generating radiation (e.g., a quantum cascade laser) having one or more frequencies in a range of about 0.1 THz to about 10 THz, and a two-dimensional detector array... | 04/06/2010 |