Bizarre Patents
Crispy Chip Sandwich and Process of Producing a Sandwich Product
A food product comprising a multilayer cookie or snack having outer layers formed from a crispy type edible food product such as a potato chip or corn chip, etc. with an intermediate marshmallow layer being in contact with the inner surface of each crispy chip and one or more filler substances.
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| Number | Title | Issue Date |
| 8173808 | Substituted naphthalenyl-pyrimidine compounds The present invention relates to substituted naphthalenyl-pyrimidine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted naphthalenyl-pyrimidine compounds and methods of trea... | 05/08/2012 |
| 8114862 | TGR5 modulators and methods of use thereof The invention relates to compounds of Formula A: or a salt, solvate, hydrate, or prodrug thereof. The compounds of Formula A are TGR5 modulators useful for the treatment of various diseases, including metabolic disease, inf... | 02/14/2012 |
| 8088768 | Protein kinase and phosphatase inhibitors The present invention provides a method for identifying inhibitors of protein kinases and/or protein phosphatases. Methods are also provided for inhibiting protein kinase and/or protein phosphatase activity. Specific non-peptide protein tyrosine kinase and/or protei... | 01/03/2012 |
| 8067472 | Methods of treating Hodgkin's and non-Hodgkin's lymphoma The present invention provides methods of selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells, and/or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inh... | 11/29/2011 |
| 8067459 | Lapachone compounds and methods of use thereof The invention provides lapachone analogs and derivatives as well as methods of use thereof. These compounds can be used in pharmaceutical compositions for the treatment or prevention of cell proliferation disorders. These compounds can also be used in the treatment ... | 11/29/2011 |
| 8058267 | Steroids as agonists for FXR The invention relates to compounds of formula (I): wherein R is ethyl and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. The compounds of formula (I) are useful as FXR... | 11/15/2011 |
| 8012690 | Bead emulsion nucleic acid amplification Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. ... | 09/06/2011 |
| 8003641 | Compositions and methods of treating cell proliferation disorders The invention relates to compounds and methods for treating cell proliferation disorders. ... | 08/23/2011 |
| 7994352 | Process for preparing 3a(β)-7a(β)-dihydroxy-6a(β)-alkyl-5β-cholanic acid Process for preparing 3α-7α(β)-dihydroxy-6α(β)-alkyl-5β-cholanic acid (I) in which R is a linear or branched C1-C5 alkyl and the relative intermediates 3α-hydroxy-6β-alkyl-7-keto-5β-cholanic (VIII) and 3α-hydroxy-6α-alkyl-7-keto-5β-... | 08/09/2011 |
| 7982012 | Compositions and methods for the therapy and diagnosis of cytomegalovirus The present invention provides novel anti-cytomegalovirus antibodies and related compositions and methods. These antibodies may be used in the diagnosis, prevention, and treatment of cytomegalovirus infection. ... | 07/19/2011 |
| 7968574 | Biaryl compositions and methods for modulating a kinase cascade The invention relates to compounds and methods for modulating one or more components of a kinase cascade. The invention relates to compounds of the formula I: or a pharmaceutically acceptable salt thereof. The compounds of ... | 06/28/2011 |
| 7941279 | Systems and methods for analyzing nanoreporters Methods, computers, and computer program products for detecting the presence of a probe within a sample overlayed on a substrate are provided. The probe comprises a plurality of spatially arranged labels. A data storage module stores a plurality of light images, whe... | 05/10/2011 |
| 7932244 | Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions The present invention relates to compounds of formula (I): wherein R is hydrogen or alpha-hydroxy, the hydroxyl group in position 7 is in the alpha or beta position; | 04/26/2011 |
| 7928216 | Nuclease resistant external guide sequences for treating inflammatory and viral related respiratory diseases External Guide Sequence (EGS) are described that target proteins required for generation and modification of the immunoglobulin and T-cell repertoire that are useful for treatment or prevention of inflammatory or related diseases. Formulations suitable for administr... | 04/19/2011 |
| 7919237 | Methods for detection and quantification of analytes in complex mixtures The invention provides a diverse population of uniquely labeled probes, containing about thirty or more target specific nucleic acid probes each attached to a unique label bound to a nucleic acid. Also provided are methods of using and producing these populations of... | 04/05/2011 |
| 7919097 | Methods of inducing IL-10 production The invention provides a method of inducing IL-10 production. ... | 04/05/2011 |
| 7902354 | Lapachone compounds and methods of use thereof The present invention provides novel tricyclic spiro-oxathiine naphthoquinone derivatives, a synthetic method for making the derivatives, and the use of the derivatives to induce cell death and/or to inhibit proliferation of cancer or precancerous cells. The naphtho... | 03/08/2011 |
| 7893034 | Regulation of oncogenes by microRNAs Naturally occurring miRNAs that regulate human oncogenes and methods of use therof are described. Suitable nucleic acids for use in the methods and compositions described herein include, but are not limited to, pri-miRNA, pre-miRNA, mature miRNA or fragments of vari... | 02/22/2011 |
| 7847122 | Polymorphs of suberoylanilide hydroxamic acid The present invention provides methods of selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells, and/or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inh... | 12/07/2010 |
| 7879865 | Treatment of cancer of the brain using histone deacetylase inhibitors The present application is directed to a method of treating diseases of the central nervous system (CNS) comprising administering to a individual in need of treatment a therapeutically effective amount of an inhibitor of histone deacetylase. In particular embodiment... | 02/01/2011 |
| 7858608 | Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions The present invention relates to compounds of formula (I) wherein: R1 is hydrogen or an alkyl group; R2 is hydrogen or a halogen, nitro, alkyloxy, amino or carboxy group; ... | 12/28/2010 |
| 7858117 | Amphoteric liposomes and their use Amphoteric liposomes are proposed, which comprise positive and negative membrane-based or membrane-forming charge carriers as well as the use of these liposomes. ... | 12/28/2010 |
| 7854927 | Methods and compositions for the dietary management of autoimmune disorders The present invention describes the use of lactic acid bacteria, particularly lactic acid producing members of the genus Bacillus, in treating digestive-related immune disorders by downregulating of cytokines and by inhibiting pathogenic or deleterious microo... | 12/21/2010 |
| 7851509 | Polymorphs of suberoylanilide hydroxamic acid The present invention provides methods of selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells, and/or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inh... | 12/14/2010 |
| 7829662 | Method of treating apoptosis and compositions thereof Disclosed herein are novel polypeptides and the nucleic acid sequences that encode them. Also disclosed are antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, ... | 11/09/2010 |
| 7820195 | Micronized device for the delivery of biologically active molecules and methods of use thereof The invention provides micronized encapsulated cell therapy devices that are capable of delivering a biologically active molecule to the eye. Also provided are methods of using the same to deliver biologically active molecules to the eye and to treat ophthalmic diso... | 10/26/2010 |
| 7812051 | Pharmaceutical compositions of β-lapachone and β-lapachone analogs with improved tumor targeting potential The present invention relates to polymer-modified quinone-containing and carbonyl-containing therapeutic agents, including polymer-modified β-lapachone compounds, and methods of treating cancer by administering the polymer-modified therapeutic agents to a subject. ... | 10/12/2010 |
| 7811818 | Human liver engrafting cells isolated from adult liver tissue A substantially enriched mammalian hepatic liver engrafting cell population is provided. Methods are provided for the isolation and culture of this liver engrafting cell. The progenitor cells are obtained from a variety of sources, including fetal and adult tissues.... | 10/12/2010 |
| 7803931 | Aptamer therapeutics useful in the treatment of complement-related disorders The invention provides nucleic acid therapeutics and methods for using these nucleic acid therapeutics in the treatment of complement-related disorders. ... | 09/28/2010 |
| 7803817 | Composition and methods for inhibiting gastric acid secretion The present invention is related to oral compositions comprising an irreversible gastric H+/K+-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and succinc acid as a parietal cell activator in the gastric lumen. The comp... | 09/28/2010 |
| 7803766 | Gastrin compositions and formulations, and methods of use and preparation The present invention concerns six novel variants of alternative splicing of the CD40 receptor The invention provides a pharmaceutical composition comprising a gastrin compound having an extended activity upon administration to a subject in comparison with na... | 09/28/2010 |
| 7786268 | Anti-IP-10 antibodies and methods of use thereof The invention relates to fully human antibodies, and fragments thereof, that bind to interferon-inducible-protein-10 (IP-10, CXCL10), thereby modulating the interaction between IP-10 and its receptor, CXCR3, and/or modulating the biological activities of IP-10. The ... | 08/31/2010 |
| 7786265 | Isolated antibodies against biologically active leptin-related peptides The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissu... | 08/31/2010 |
| 7786099 | Aromatic a-ring derivatives of tetracycline compounds Aromatized A-ring derivatives of tetracycline compounds are described. ... | 08/31/2010 |
| 7785784 | Detection of oligonucleotides by dual hybridization The invention provides methods and compositions for detecting and/or quantifying modified nucleic acid oligonucleotides. These methods and compositions are useful for detecting and quantifying diagnostic and/or therapeutic synthetic modified oligonucleotides, such a... | 08/31/2010 |
| 7780983 | Amphoteric liposomes Amphoteric liposomes are proposed, which comprise positive and negative membrane-based or membrane-forming charge carriers as well as the use of these liposomes. ... | 08/24/2010 |
| 7744884 | Neutralizing antibodies and methods of use thereof This invention provides monoclonal antibodies that recognize the Toll-like Receptor 4/MD-2 receptor complex, and monoclonal antibodies that recognize the TLR4/MD2 complex as well as TLR4 when not complexed with MD-2. The invention further provides methods of using t... | 06/29/2010 |
| 7741306 | Regulation of oncogenes by microRNAs Naturally occurring miRNAs that regulate human oncogenes and methods of use thereof are described. Suitable nucleic acids for use in the methods and compositions described herein include, but are not limited to, pri-miRNA, pre-miRNA, mature miRNA ,or fragments of va... | 06/22/2010 |
| 7741061 | Polysaccharide structure and sequence determination The invention provides a method for the structural analysis of a saccharide, comprising: a) providing on a surface a plurality of essentially sequence- and/or site-specific binding agents; b) contacting said surface with a saccharide to be analyzed, or with a mixtur... | 06/22/2010 |
| 7732658 | Composition and method for imaging cells The invention relates to compositions containing a polynucleotide encoding for a reporter gene, a selectable marker and a regulatory element, that provide a method for imaging cells in vivo. ... | 06/08/2010 |
