Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 8178531 | Antiviral agents The present invention relates to antiviral compounds of formula (I), compositions containing these compounds, processes for their preparation, intermediates in their synthesis, and their use as therapeutics for prevention o... | 05/15/2012 |
| 8163707 | 4′-allene-substituted nucleoside derivatives The present invention discloses compounds of formula (I), or its β-L enantiomer, or a pharmaceutically acceptable salt, ester, stereoisomer, tautomer, solvate, prodrug, or combination thereof: which inhibit, preventing or ... | 04/24/2012 |
| 8124584 | Macrocyclic hepatitis C serine protease inhibitors The present invention relates to compounds of Formula I, II or III, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: wherein W is a substituted or unsubstituted heterocyclic ring s... | 02/28/2012 |
| 8123906 | Functionalization of paper components Compositions and methods of producing paper-based materials are disclosed. In general, the techniques utilize an amine-containing polymer, such as chitosan, to functionalize one or more components of a mixture used to form materials such as paper-based materials. Su... | 02/28/2012 |
| 8119616 | Formulation of quinazoline based EGFR inhibitors containing a zinc binding moiety The present invention relates to a composition comprising an inclusion complex of a cyclodextrin and quinazoline containing zinc-binding moiety based derivatives. The cyclodextrin is preferable a β-cyclodextrin or a derivative thereof. The quinazolines have enhance... | 02/21/2012 |
| 8105393 | Pigment compositions for hair coloring Compositions and methods relating to the use of pigment compositions are revealed, which can be used to impart color to hair. For instance, treatment formulations that include a pigment-functionalized cationic polymer can be utilized. In some particular instances, a... | 01/31/2012 |
| 8101643 | Benzimidazole derivatives The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the co... | 01/24/2012 |
| 8071101 | Antibody therapy for treatment of diseases associated with gluten intolerance The present invention includes a pharmaceutical compositions and methods for treating diseases associated with gluten intolerance in a patient, comprising: administering to the patient an effective amount of an antibody having specific activity against gluten or glu... | 12/06/2011 |
| 8039653 | Methods and apparatus for removal of degradation byproducts and contaminants from oil for use in preparation of biodiesel Methods, particles, and devices are disclosed for filtration of oil for use of the oil in the preparation of biodiesel. Disclosed particles may comprise a substantially inert porous particle with a coating comprising a polymer having amine, amino, and/or imine group... | 10/18/2011 |
| 8034388 | Anthocyanin-rich compositions and methods for inhibiting cancer cell growth The present invention provides compositions and methods for inhibiting the growth and cell cycle progression in carcinoma cells comprising the step of contacting the cells with an anthocyanin rich extract (ARE) in an amount effective to inhibit the growth and cell c... | 10/11/2011 |
| 8030307 | Bicyclic, C5-substituted proline derivatives as inhibitors of the hepatitis C virus NS3 protease The present invention relates to compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4... | 10/04/2011 |
| 7994489 | Skin tanning and light therapy incorporating light emitting diodes The invention relates to a skin tanning chamber, the improvement comprising at least one light emitting diode emitting a UVA light, such as a UVA LED that emits essentially only UVA. Additionally, multiple LEDs of varying types with various characteristic wavelength... | 08/09/2011 |
| 7985819 | Styrene-maleic anhydride copolymers for bioapplications and their preparation The present invention discloses styrene-maleic anhydride copolymers preparations using solventless techniques. The solventless method resulted in reduced amounts of residues, such as unreacted styrene and/or maleic anhydride monomers, which makes the copolymers part... | 07/26/2011 |
| 7977347 | Quinazoline based EGFR inhibitors The present invention relates to quinazoline containing zinc-binding moiety based derivatives of formula I that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR... | 07/12/2011 |
| 7968084 | Nanoscopic hair care products The present invention is directed to a hair treatment preparation comprising a payload in an intimate relationship to a polymeric nanostructure, the polymeric nanostructure being reactive to hair or capable of being immobilized onto or in hair. The nanoscopic nature... | 06/28/2011 |
| 7954491 | Low dose pharmaceutical powders for inhalations The invention relates to a method of delivering an agent to the pulmonary system of a compromised patient, in a single breath-activated step, comprising administering a particle mass comprising an agent from an inhaler containing less than 5 milligrams of the mass, ... | 06/07/2011 |
| 7947742 | Inhalable epinephrine The present invention is directed toward particles for delivery of epinephrine to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable compositions comprising the particles of the present invention described ... | 05/24/2011 |
| 7947458 | Placental human neurokinin B precursor Methods of diagnosing pregnancy induced hypertension or pre-eclampsia by the measurement of the production of neurokinin B, its precursor and fragments thereof are provided, as are kits for use in the methods. Treatments of the conditions and methods of preparing su... | 05/24/2011 |
| 7938372 | Free standing or vehicle mounted 6-axis positionable tray, positionable shelf, cup-holder, stanchion apparatus and related systems An apparent need exists for compact devices to ergonomically support such items as laptop computers, keyboards and projectors. The AIRDESK® desk/stand design positions such items with full 3D positioning using all 6 directions of adjustment. Each direction of motio... | 05/10/2011 |
| 7928136 | Substituted 2-indolinone as PTK inhibitors containing a zinc binding moiety The present invention relates to substituted 2-indolinone containing zinc-binding moiety based derivatives that have enhanced or unique properties as inhibitors of protein tyrosine kinase (PTK) receptors and their use in the treatment of PTK related diseases and dis... | 04/19/2011 |
| 7919627 | Processes for the preparation of hydroxylamines The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acce... | 04/05/2011 |
| 7919499 | Naltrexone long acting formulations and methods of use The inventions described herein arose from unexpected discoveries made during clinical trials with a long acting formulation of naltrexone. As such, the invention includes a method for treating an individual in need of naltrexone comprising the step of parenterally ... | 04/05/2011 |
| 7918027 | Razor head The present invention relates to razor heads and further to razors which include razor heads as defined. In one aspect of the invention the razor heads comprise at least one blade defining a plurality of cutting edges. The cutting edges are arranged to intercept at ... | 04/05/2011 |
| 7915387 | Monoclonal antibody Sc104 and derivative thereof specifically binding to a sialyltetraosyl carbohydrate as a potential anti-tumor therapeutic agent The present invention provides an isolated specific binding member capable of binding a sialyltetraosly carbohydrate and directly inducing cell death without the need for immune effector cells. Such a binding member may be an antibody or a part thereof. Also provide... | 03/29/2011 |
| 7897563 | Use of oligomers and polymers for drug solubilization, stabilization, and delivery The invention relates to the use of oligomers and polymers capable of rendering insoluble drugs soluble, protecting unstable drugs, and facilitating the delivery of drugs to their site of action. This invention further relates to processes for the preparation of suc... | 03/01/2011 |
| 7888556 | Root cap specific promoter and methods of use in plants The invention provides an AtCel5 promoter isolated from Arabidopsis thaliana that is expressed exclusively in root cap cells of both primary and secondary roots. AtCel5 is believed to be a soluble and secreted protein that plays a role in the sloughing of roo... | 02/15/2011 |
| 7888361 | Tyrosine kinase inhibitors containing a zinc binding moiety The present invention relates to tyrosine kinase inhibitors that contain a zinc-binding moiety and their use in the treatment of tyrosine related diseases and disorders such as cancer. The said derivatives may further act as HDAC inhibitors. ... | 02/15/2011 |
| 7846938 | Tartrate salts of quinazoline based EGFR inhibitors containing a zinc binding moiety The present invention relates to tartrate salts of quinazoline containing zinc-binding moiety based derivatives of Formula II, below. These compounds are inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK... | 12/07/2010 |
| 7846747 | Biocatalytic solgel microarrays A system and method for conducting high-throughput interactions between test compositions and analytes, comprising one or more test compositions, and a plurality of independent micromatrices, wherein each said micromatrix encapsulates at least one said test composit... | 12/07/2010 |
| 7879358 | Pulmonary delivery for levodopa In one aspect, the invention is related to a method of treating a patient with Parkinson's disease, the method including administering to the respiratory tract of the patient particles that include more than about 90 weight percent (wt %) of levodopa. The particles ... | 02/01/2011 |
| 7871963 | Tunable surfactants for oil recovery applications The systems and methods described herein provide for modified lignins and other compositions that may be useful as surfactants. These compositions have particular utility for energy-related applications. In embodiments, they may be useful for enhanced oil recovery. ... | 01/18/2011 |
| 7854929 | Method for treating lateral epicondylitis using collagenase Methods for treatment by collagenase injections are provided, which are effective in dissolving and lysing a collagenase septa network to treat carpal tunnel, plantar fasciitis and lateral epicondylitis conditions. The methods treat such conditions by injecting or o... | 12/21/2010 |
| 7842813 | Processes for the preparation of O-[5-(4-amino-thiazol-2-yl)-pyridin-2-ylmethyl]-hydroxylamine The present invention relates generally to novel methods for the synthesis of O-[5-(4-amino-thiazol-2-yl)-pyridin-2-ylmethyl]-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceuti... | 11/30/2010 |
| 7829551 | Method and composition for the control of arthropods The present invention relates to the use of certain siloxanes and mixtures thereof in the control of arthropods such as insects and arachnids, and in particular ectoparasites, such as head lice. ... | 11/09/2010 |
| 7824673 | Reduction of adipose tissue A simple search was made on the Internet. There were at least a few hundred entries. The following seem to be the best of the few dozen examined. The first page of each is cited below for identification. ... | 11/02/2010 |
| 7811560 | Compositions and methods for treating collagen-mediated diseases A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product includes collagenase I and collagenase II in a ratio of about 1 to 1, with a purity of greater than at le... | 10/12/2010 |
| 7754242 | Inhalable sustained therapeutic formulations The present invention is based, in part, on the unexpected discovery that particles for pulmonary delivery of a therapeutic, prophylactic or diagnostic agent that comprise a phospholipid and a sufficient amount of leucine can produce sustained effect of the agent. S... | 07/13/2010 |
| 7741283 | Compositions and methods for inhibiting cell proliferation Disclosed are compositions and methods useful in the regulation of cell proliferation. The invention provides TGF-β (transforming growth factor β) and IGFBP-3 (insulin like growth factor binding protein 3) as ligands that engage LRP (low density lipoprotein recept... | 06/22/2010 |
| 7728148 | Acyclic oximyl hepatitis C protease inhibitors The present invention discloses compounds of formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A... | 06/01/2010 |
| 7723473 | Peptide antagonists of TGF-beta family members and therapeutic uses thereof This invention is drawn to methods of using peptide-based antagonists of TGF-beta to facilitate the healing of cutaneous wounds that includes burns, lacerations and scrapes. The administration of peptide TGF-beta antagonists to wounds results in reduced scarring, wo... | 05/25/2010 |
