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| Number | Title | Issue Date |
| RE42832 | Method for reforming organics into shorter-chain unsaturated organic compounds A method is disclosed for reforming organics into shorter-chain unsaturated organic compounds. A molten metal bath is provided which can cause homolytic cleavage of an organic component of an organic-containing feed. The feed is directed into the molten metal bath a... | 10/11/2011 |
| 7811560 | Compositions and methods for treating collagen-mediated diseases A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product includes collagenase I and collagenase II in a ratio of about 1 to 1, with a purity of greater than at le... | 10/12/2010 |
| 7671258 | Surfactant peptide nanostructures, and uses thereof This work describes a new class of short polypeptides that can self-assemble to form regular nanotubes with an average diameters of about 50 nm. These peptides (7 to 8 amino acids) have a structure very similar to those observed in surfactant molecules with a define... | 03/02/2010 |
| 7601709 | Macrocyclic hepatitis C serine protease inhibitors The present invention relates to compounds of Formula I, II or Ill, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: wherein W is a substituted or unsubstituted heterocyclic ring system. The compounds inhibi... | 10/13/2009 |
| 7517859 | Spirocyclic bicyclolides The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical comp... | 04/14/2009 |
| 7469488 | Control of process humidity to produce large, porous particles Spray dried particles having specified aerodynamic characteristics are produced by atomizing a liquid feed and contacting the liquid feed with a drying gas, such as, for example, air or nitrogen. The humidity of the drying gas is controlled to a value, expressed, fo... | 12/30/2008 |
| 7468419 | Cyclosporin derivatives for the treatment of immune disorders The present invention relates to a cyclosporin analog of the following formula (I) or a pro-drug or pharmaceutically acceptable salt thereof: wherein A is of the formula: | 12/23/2008 |
| 7419962 | 3,6-bicyclolides The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical com... | 09/02/2008 |
| 7414030 | 6-11 Bicyclic erythromycin derivatives The present invention discloses compounds of formulaes I, II, III, or IV, or a racemate, enantiomer, regioisomer, salt, ester or prodrug thereof: which exhibit antibacterial properties. The present invention further relates... | 08/19/2008 |
| 7407942 | 3,6-bridged 9,12-oxolides The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical com... | 08/05/2008 |
| 7402568 | Bicyclic 9a-azalide derivatives The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceuti... | 07/22/2008 |
| 7384921 | Polymorphic forms of 6-11 bicyclic ketolide derivatives The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are provided methods of producing... | 06/10/2008 |
| 7384922 | 6-11 bridged oxime erythromycin derivatives The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical comp... | 06/10/2008 |
| 7384649 | Particulate compositions for pulmonary delivery This invention concerns an improved particulate composition for delivering a drug to the pulmonary system. Applicants disclose a method of identifying an optimal form of aerodynamically light particles which are highly dispersible. The particles of the instant inven... | 06/10/2008 |
| 7368452 | Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors The present invention relates to compounds of Formula I or II, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) ... | 05/06/2008 |
| 7312201 | Tetracyclic bicyclolides The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmace... | 12/25/2007 |
| 7291602 | 11,12-lactone bicyclolides The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmace... | 11/06/2007 |
| 7276487 | 9a, 11-3C-bicyclic 9a-azalide derivatives The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmace... | 10/02/2007 |
| 7273853 | 6-11 bicyclic ketolide derivatives The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmace... | 09/25/2007 |
| 7271155 | 9A, 11-2C-bicyclic 9a-azalide derivatives The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to ... | 09/18/2007 |
| 7265094 | 9-substituted 6-11 bicyclic erythromycin derivatives The present invention discloses compounds of formula I, II, III, or IV, or a racemate, enantiomer, regioisomer, salt, ester or prodrug thereof: which exhibit antibacterial properties. The present invention furthe... | 09/04/2007 |
| 7240478 | Highly supercharged regenerative gas turbine The present invention comprises a highly supercharged, regenerative gas-turbine system. The gas turbine comprises a compressor, a regenerator, a combustor, and an expander. A pre-compressor pressurizes air going into the compressor section of the gas turbine. A cool... | 07/10/2007 |
| 7229972 | 3,6-Bicyclolides The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmac... | 06/12/2007 |
| 7189704 | 6-11 bicyclic ketolide derivatives The present invention discloses, inter alia, a compound of the following formula, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention f... | 03/13/2007 |
| 7168235 | Highly supercharged regenerative gas turbine The present invention comprises a highly supercharged, regenerative gas-turbine system. The gas turbine comprises a compressor, a regenerator, a combustor, and an expander. A pre-compressor pressurizes air going into the compressor section of the gas turbine. A cool... | 01/30/2007 |
| 7162993 | Intersecting vane machines The invention provides a toroidal intersecting vane machine incorporating intersecting rotors to form primary and secondary chambers whose porting configurations minimize friction and maximize efficiency. Specifically, it is an object of the invention to provide a t... | 01/16/2007 |