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Attorney: Elmer; James Scott


Number of patents: 16
Last date: December 07, 1999

NumberTitleIssue Date
5998654Retinoic acid receptor antagonist compounds and methods
Trienoic compounds having activity as antagonists for retinoic acid receptors are provided. Also provided are pharmaceutical compositions incorporating such compounds and methods for their therapeutic use....
12/07/1999
5580559Hybrid plasminogen activator
Novel single-chain hybrid plasminogen activators having an amino acid sequence composed of at least two subsequences corresponding in amino acid identity and number to subsequences of human t-PA and of human u-PA, and mutants thereof in which at least one...
12/03/1996
5571894Recombinant antibodies specific for a growth factor receptor
The invention concerns recombinant antibodies directed to the extracellular domain of the human growth factor receptor c-erbB-2 comprising a light chain variable domain and a heavy chain variable domain of a monoclonal antibody, monoclonal antibodies dire...
11/05/1996
5563074Immunological detection methods
The present invention relates to monoclonal antibodies that are distinguished by a high degree of selectivity and affinity towards triasulfurone and that are therefore outstandingly suitable for use in an immunoassay for the rapid and effective detection ...
10/08/1996
5559007Bacterial shuttle vectors
The invention relates to the field of genetic engineering and provides novel DNA molecules which comprise multifunctional origins of replication and/or a DNA sequence coding for the most abundant protein in the supernatant of cultures of Lactococcus Spec....
09/24/1996
5558997Monoclonal antibodies to mycosphaerella species
The invention relates to monoclonal antibodies that react specifically with members of the genus Mycosphaerella and hybridomas that produce such antibodies. The invention is further directed to a method for making a hybridoma cell line that produces monoc...
09/24/1996
5541310Herbicide resistant plants
Disclosed are plants, plant tissue and plant seed, whose growth and development are tolerant of, or resistant to various imidazole and triazole herbicidal compounds, at levels which normally are inhibitory to the plants. The tolerance or resistance is con...
07/30/1996
5534409Cytokine regulated transcription factor
The present invention discloses isolated nucleic acids encoding MGF and recombinant proteins encoded thereby. In addition to being useful for the production of recombinant MGF, these nucleic acids are also useful as probes. In a further aspect of the inve...
07/09/1996
5530195Bacillus thuringiensis gene encoding a toxin active against insects
The present invention is drawn to a novel toxin gene purified and isolated from Bacillus thuringiensis var kurstaki and given the designation CryIE(c). The novel toxin gene encodes a protein of approximately 130 kDa in size and is active against Lepidopte...
06/25/1996
5519125Plant adenylosuccinate synthetase and DNA coding therefor
The present invention provides novel plant DNA sequences coding for native adenylosuccinate synthetase (ADSS). Methods for using the complete or partial ADSS coding sequence as a probe for diagnostic, mapping and other purposes are taught. Generation of t...
05/21/1996
5508184Process for transforming plant protoplast
The present invention relates to an improved process for transforming plant protoplasts using simple, purely chemical, process steps, and to the plant material obtainable by this method. The transfer of the genetic material into the plant cell is carried out ...
04/16/1996
5501975DNA molecules encoding an ER-located endoprotease
The invention concerns novel DNA molecules encoding a modified, endoplasmic reticulum-located "dibasic processing endoprotease" and the use of said endoplasmic reticulum-located "dibasic processing endoprotease" for the correct processing of heterologous ...
03/26/1996
5466585Interferon-induced human protein in pure form, monoclonal antibodies thereto, and test kits containing these antibodies
The invention relates to purified proteins induced in human cells by interferon ଱ or ଲ, RNAs, DNAs and hybrid vectors coding for said proteins, hosts transformed with such a hybrid vector, processes for the preparation and purification of thes...
11/14/1995
5447862Pectin lyase genes of aspergillus niger
Recombinant DNA molecules coding for pectin lyase (PL) expression systems and derivatives thereof, such as the structural genes of PLA, PLB, PLC, PLD, PLE and PLF, and corresponding regulatory sequences, e.g. promoter, signal and terminator sequences, and...
09/05/1995
5422249Process for the manufacture of thrombin inhibitors
The invention relates to DNA sequences that code for the amino acid sequence of the thrombin inhibitor hirudin, hybrid vectors containing such DNA sequences, host cells transformed with such hybrid vectors, novel polypeptides with thrombin-inhibiting acti...
06/06/1995
5397697Identification of plant-responsive genes of bacteria
The invention is a method for identifying and cloning bacterial genes that are responsive to the presence of a plant host, comprising mutating a bacterial culture with a transposon containing a promoterless marker gene, exposing the bacterial mutants to r...
03/14/1995
 
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