A helium-filled sun shade for protecting individuals engaged in outdoor activities.
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| Number | Title | Issue Date |
| 7858662 | Medicament for the treatment of viral skin and tumour diseases The invention relates to a medicament containing a compound of general formula (1), where R1=independently, a straight or branched, saturated, singly- or multiply-unsaturated, optionally substituted C11-C21 alkyl, alkylene or alkynyl... | 12/28/2010 |
| 7811785 | Anti-VEGF antibodies Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding... | 10/12/2010 |
| 7803981 | Transgenic ungulates capable of human antibody production The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expre... | 09/28/2010 |
| 7758859 | Anti-VEGF antibodies Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding... | 07/20/2010 |
| 7691977 | Anti-VEGF antibodies Anti-VEGF antibodies and variants thereof, including those having high affinity for binding to VEGF, are disclosed. Also provided are methods of using phage display technology with naïve libraries to generate and select the anti-VEGF antibodies with desired binding... | 04/06/2010 |
| 7652192 | Cloning of transgenic unglulates comprising artificial chromosomes The invention is directed in part to totipotent cells that have one or more artificial chromosomes; processes for producing such cells; processes for using such cells (e.g., nuclear transfer); transgenic embryos and transgenic animals cloned from such cells; and pro... | 01/26/2010 |
| 7491534 | Methods for altering cell fate to generate T-cells specific for an antigen of interest The invention provides methods for altering the expression profile of a cell to convert the cell from one cell type to a desired cell type (e.g., T-cells). These reprogrammed cells may be used in a variety of medical applications for treating a mammal in need of a p... | 02/17/2009 |
| 7420099 | Transgenic animals and uses thereof In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or ... | 09/02/2008 |
| 7235558 | Inhibitors of the GPIb—vWF interaction, their preparation and use The present invention relates to compounds of the formula I, in which R1, R2, A, B, D, F, n, m and o have the meanings indicated herein. The compounds of the formula I are valuable pharmacologically active compounds. They are reversible inhibitors of the interaction... | 06/26/2007 |
| 6133025 | Compact Epstein-Barr virus replicons Disclosed herein are nucleic acid sequences which support episomal replication in a mammalian cell. These nucleic acid sequences, which have a length of less than 3 kb, include (a) an OriP sequence and (b) an EBNA1 sequence operably linked to a promoter.... | 10/17/2000 |
| 6114148 | High level expression of proteins The invention features a synthetic gene encoding a protein normally expressed in a mammalian cell wherein at least one non-preferred or less preferred codon in the natural gene encoding the protein has been replaced by a preferred codon encoding the same ... | 09/05/2000 |