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Attorney: Eisenberg, Esq.; Howard


Number of patents: 40
Last date: May 22, 2012

NumberTitleIssue Date
8182833Method and kit for reducing the symptoms of peripheral vascular disease with topical progesterone
A method for reducing the symptoms of peripheral vascular disease and for improving peripheral circulation wherein a progestin is administered to a subject in need thereof. ...
05/22/2012
8143227Azithromycin for treatment of skin disorders
Azithromycin has increased efficacy in treating acne and other skin conditions when administered systemically at low doses, below those previously known to produce a clinical antibiotic effect. ...
03/27/2012
8124123Controlled release azithromycin solid dosages forms
A solid dosage form for oral administration comprising azithromycin in an amount below that which causes gastrointestinal side effects, which dosage form is a controlled release dosage form. ...
02/28/2012
8039494Compositions and methods for treating diseases of the nail
Methods and compositions for treating disorders of the nail and nail bed. Such compositions contain a vehicle in which all components of the composition are dissolved, suspended, dispersed, or emulsified, a non-volatile solvent, a wetting agent, and a pharmaceutical...
10/18/2011
7893097Methods and compositions for increasing solubility of azole drug compounds that are poorly soluble in water
The combination of any two of a polyol, a polyol ether, and a low carbon organic alcohol provides a synergistic effect on the solubility of azole compounds, such as metronidazole, in aqueous fluid. ...
02/22/2011
7829523Method for stabilizing polypeptides lacking methionine
Methionine is an effective antioxidant for polypeptides having an amino acid sequence lacking methionine. Compositions containing polypeptides having an amino acid sequence that is free of methionine residues are stabilized from oxidative degradation by combining me...
11/09/2010
7794939Methods of DNA methylation detection
The present invention provides for methods of DNA methylation detection. The present invention provides for methods of generating and detecting specific electronic signals that report the methylation status of targeted DNA molecules in biological samples. Two...
09/14/2010
7740864Vaccines for diseases of fish
Fish are immunized by a mass vaccination method, such as by immersion in water containing an attenuated strain of a pathogenic bacterium that does not effectively cause disease in fish when the non-attenuated pathogenic bacterium is exposed to the fish by immersion....
06/22/2010
7713715Method for diagnosing infections
Antigens are removed from the surface of an organism, such as a microorganism, without disrupting the organism and releasing internal antigens of the organism. The free surface antigens of the organism may be used to determine the presence of infection in an animal ...
05/11/2010
7705197Embryo development and survival
An embryo that is transferred into the uterus of a recipient female is protected from embryotoxic effects of prostaglandin F2α by exposing the embryo to a prostaglandin antagonist. ...
04/27/2010
7674783Estrogen beta receptor agonists to prevent or reduce the severity of cardiovascular disease
A method for preventing or treating vascular hyperreactivity in which a chemical compound that is an estrogen beta receptor agonist is administered to a subject suffering from or at risk of vascular hyperreactivity. Preferably, the administration is topically to the...
03/09/2010
7629116Type I interferon-inducible proteins to detect viral infection
A method for determining the presence of a viral infection in an animal not known to have been infected with a virus or other disease-causing microbial organism by determining the level of Mx protein or other Type I Interferon-inducible protein in the animal. ...
12/08/2009
7572780Method and kit for reducing the symptoms of peripheral vascular disease
A method for reducing the symptoms of peripheral vascular disease wherein a chemical agent that reduces peripheral vascular hyperreactivity in response to a stimulus for contraction of peripheral vascular musculature is administered to a subject in need thereof. Kit...
08/11/2009
7560120Vehicles for delivery of biologically active substances
A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers. Methods for making and using are disclosed, as are kits for administratio...
07/14/2009
7524511Method and kit for moisturizing the surface of the eye
A method for moisturizing the eye in which an amount of aqueous fluid is administered to the eye in an amount below that which causes flooding of the eye and removal of the normal tear film from the surface of the eye. The fluid, when administered in accordance with...
04/28/2009
7517955adhesion molecule
A polypeptide, designated as “Streptococcus uberis Adhesion Molecule” (SUAM), and fragments of SUAM, prevent internalization and adherence of Streptococcus uberis and other streptococcal pathogens to cells. The SUAM polypeptide and fragments may be...
04/14/2009
7422869Method for diagnosing infectious diseases
A method for diagnosing the presence in an animal of an infection due to a microorganism in which a test sample obtained from the animal is exposed to a population of the microorganism and the presence of binding of the microorganism by an antibody in the test sampl...
09/09/2008
7368122Skin cream
An emulsion for topical application to the skin containing a high molecular weight emulsifier and substantially no emulsifiers of a molecular weight less than 100 kD. The emulsion may be used to prevent or treat dermatoses and may additionally contain pharmaceutical...
05/06/2008
7348317Aqueous compositions containing metronidazole
An aqueous solution of metronidazole in which the concentration of metronidazole is higher than 0.75%. The solution contains a combination of solubility-enhancing agents, one of which is a cyclodextrin such as beta-cyclodextrin and the second is niacin or niacinamid...
03/25/2008
7326408Topical acne vulgaris medication with a sunscreen
Increased compliance in the use of topical sunscreens is obtained by combining a topical sunscreen agent in a formulation containing an antibacterial medication such as azelaic acid or an antibiotic. ...
02/05/2008
7323620Activation of equine oocytes
A method for activating an equine oocyte comprising exposing oocyte to a medium containing a concentration of calcium of at least about 4 mM. Preferably the oocyte is exposed to this concentration of calcium during activation. ...
01/29/2008
7276350Method for diagnosing infectious diseases
A method for diagnosing the presence in an animal of an infection due to a microorganism in which a test sample obtained from the animal is exposed to a population of the microorganism and the presence of binding of the microorganism by an antibody in the test sampl...
10/02/2007
7252816Topical acne vulgairs medication with a sunscreen
Increased compliance in the use of topical sunscreens is obtained by combining a topical sunscreen agent in a formulation containing an antibacterial medication such as azelaic acid or an antibiotic. ...
08/07/2007
7160696Bovine lymphocyte-derived antibacterial protein
A nucleic acid sequence encoding a polypeptide having antibacterial activity, which nucleic acid sequence has the nucleotide sequence of Bases 198 to 452 of Seq. ID No. 13 or is a nucleic acid that hybridizes under highly stringent conditions to a complement of a nu...
01/09/2007
7125728Determination of pregnancy status in cattle and sheep
A method and kit for determining whether an animal is not pregnant, or is pregnant following a breeding. The level of expression of a pregnancy induced protein is determined in an animal for which pregnancy status information is desired and the level is compared to ...
10/24/2006
7067321Polyglutamine repeat sequences
Several neurodegenerative diseases result from the aggregation of polyglutamine repeat proteins into insoluble neuronal intranuclear inclusions. The invention provides methods with which to study the processes of these diseases, including methods for solubilizing po...
06/27/2006
7041859Method for halogenating or radiohalogenating a chemical compound
A method for obtaining a halogenated organic compound, whereby an organotrifluoroborate compound is reacted with a halide ion in the presence of an oxidizing agent to produce the corresponding halogenated organic compound. The method may be used for producing radioh...
05/09/2006
6960346Vehicles for delivery of biologically active substances
A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers. Methods for making and using are disclosed, as are kits for administratio...
11/01/2005
6936637Prevention of apoptosis in non-cancerous cells
Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is observed to a le...
08/30/2005
6916852Method for regulation of microvascular tone
Methods and kits for regulating arterial microvascular tone in which a COX-2 inhibitor and a cannabinoid receptor agonist are co-administered to a subject. ...
07/12/2005
6881726Aqueous compositions containing metronidazole
An aqueous solution of metronidazole in which the concentration of metronidazole is higher than 0.75%. The solution contains a combination of solubility-enhancing agents, one of which is a cyclodextrin such as beta-cyclodextrin and the second is a compound other tha...
04/19/2005
6645715Artificial cornea
The invention provides an in vitro avascular human corneal equivalent that comprises immortalized human cell lines. As these corneal equivalents are in vitro models, they are maintained in an incubator throughout the testing period, thereby eliminating th...
11/11/2003
6602487Methods and tests for producing and for inhibiting coronary artery vasospasms
Methods for producing coronary vasospasms and for inhibiting coronary vasospasms are disclosed. Both in vivo and in vitro methods are disclosed. The methods are useful as tests for determining the ability of a chemical compound to inhibit or reduce corona...
08/05/2003
6593457Lymphocyte-derived antimicrobial protein (LDAP) and methods of isolating and producing and using the protein
A purified, soluble lymphocyte-derived antimicrobial protein that has a molecular weight of 16 kD on SDS-PAGE, is inactivated by heating at 56° C. for 30 minutes or by treatment with trypsin, is expressed by CD3-, CD2+ cytokine-stimulated cells', and is ...
07/15/2003
6589922Skin cleanser comprising a steareth, poloxamer, and a glyceryl monoester
A non-irritating skin cleanser that contains water, a non-ionic surfactant, and a glyceryl monoester of a fatty acid. The skin cleanser is especially useful for cleansing irritated, diseased, damaged, or sensitive skin. The cleanser is especially useful f...
07/08/2003
6511969Method for reducing coronary artery reactivity
A method for reducing coronary artery reactivity. A predetermined amount of natural progesterone is provided by a convenient and pleasant delivery system to the blood stream, sufficient to reduce the likelihood of coronary vasospasm and myocardial ischemi...
01/28/2003
6498192Prevention of apoptosis in non-cancerous cells
Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is obser...
12/24/2002
6423315Synthetic peptide for treatment of autoimmune arthritis
Peptides that are capable of suppressing autoimmune arthritis are disclosed. The polypeptides described by the present invention which are capable of suppressing autoimmune arthritis in mammals include analogues of CII 245-270. The peptides do not provoke...
07/23/2002
6357394Cage for housing dangerous animals
A cage for housing animals, particularly for dangerous animals like venomous snakes, is disclosed. The cage has at least two compartments, one of which is an externally sealable drawer that can be removed from the cage by sliding it from the other compone...
03/19/2002
6108818Skin adherent sweat band
A novel sweat band absorbs perspiration on the forehead, permits unrestricted air flow to portions of the head other than the forehead, and does not dishevel the wearer's hair. The sweat band secures to a person's head in a manner other than encircling th...
08/29/2000
 
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