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| Number | Title | Issue Date |
| 5602166 | Cytokine inhibitors Invented are methods of inhibiting the production of cytokines, particularly inhibiting the production of interleukin-1 and inhibiting the production of tumor necrosis factor in a mammal in need thereof which comprises administering to such mammal an effe... | 02/11/1997 |
| 5594026 | Polymorphs of crystalline mupirocin Two further crystalline polymorphic forms of the anti-infective agent mupirocin have been identified. Processes for the preparation thereof and the use thereof are described.... | 01/14/1997 |
| 5591748 | Immunomodulatory azaspiranes Invented are substituted azaspirane compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to induce an immunosuppressive effect in a mammal in need thereof.... | 01/07/1997 |
| 5561124 | 17--acyl steroids which inhibit 5--reductase The invention relates to substituted 17-acyl steroidal 5-reductase inhibiting compounds. The invention also relates to pharmaceutical compositions containing these compounds and their use for reducing prostate size and treating prostate aden... | 10/01/1996 |
| 5536745 | (Hetero)-aryl ketones derivatives with antibacterial properties Conformationally restricted aryl and heteroaryl ketones derived from monic acid have useful antibacterial properties.... | 07/16/1996 |
| 5527806 | 17 and 17ଲ substituted acyl 4 aza steroids Invented are 17ଲ-substituted acyl-4-aza analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods for using these compounds to inhibit steroid 5--reductase. Also invented are intermediates... | 06/18/1996 |
| 5516768 | Uncompetitive inhibition of steroid and 5-reductose Invented are compositions of competitive and uncompetitive inhibitors of steroid 5--reductase, pharmaceutical compositions containing the compositions of inhibitors and methods of using these compositions to inhibit steroid 5--reductase. Als... | 05/14/1996 |
| 5496556 | Method of treating prostatic adenocarcinoma Invented is a Method of Treating Prostatic Adenocarcinoma by employing asteroid 5--reductase inhibiting compound or a combination of steroid 5--reductase inhibiting compounds.... | 03/05/1996 |
| 5482959 | Method for delaying aids in an HIV infected individual by administration of substituted azaspirane compounds Invented is a method of preventing or delaying the occurrence of acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus (HIV) seropositive humans which comprises administering to such human an effective therefor amount of a substituted ... | 01/09/1996 |
| 5455247 | Methods for the treatment of hyperlipidemia using azaspiranes Invented is a method of treatment of hyperlipidemia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective therefor amount of a substituted azaspirane.... | 10/03/1995 |
| 5447954 | Phenylderivate as inhibitors of ATP citrate lyase Compounds of the formula ##STR1## where the substituents are defined in the specification useful in the treatment of hyperlipidemia.... | 09/05/1995 |
| 5441731 | Compounds Polymethacrylate polymers, pharmaceutical compositions containing them and their use in medicine as cholesterol lowering agents. A particular polymer of the invention is 11-N,N,N-trimethylammonioundecyl methacrylate chloride copolymer.... | 08/15/1995 |
| 5395848 | Methods of treating hyperlipidemia with substituted azaspiranes This invention discloses a method of treating hyperlipidemia in a mammal by administering an effective amount of a substituted azaspirane.... | 03/07/1995 |
| 5300294 | Method of treating prostatic adenocarcinoma Invented is a Method of Treating Prostatic Adenocarcinoma by employing a steroid 5--reductase inhibiting compound or a combination of steroid 5--reductase inhibiting compounds.... | 04/05/1994 |
| 5273740 | Polystyrene anion exchange polymers Polystyrene polymers bearing a quaternary ammonium group are disclosed. They are useful in the treatment of hypercholesterolaemia and the prevention of atherosclerosis. A compound of the invention is 6-(N,N-dimethyl-N-octylammonio)hexanoylated polystyrene... | 12/28/1993 |
| 5230885 | Polystyrene anion exchange polymer pharmaceutical composition Polystyrene polymers having a quaternised ammonium group and their use in a method of treatment of hypercholesterolaemia. A particular compound of the invention is (N,N-dimethyl-N-dodecyl-ammoniomethylstyrene-ethyl methacrylate-divinylbenzene co-polymer, ... | 07/27/1993 |
| 5204336 | Naphthyl-,tetrahydronaphthyl-, and indanyl-substituted G-em-diphosphonates and process of use to treat hyperlipidemia Substituted gem-diphosphonate compounds having use as cholesterol lowering agents are disclosed. A compound of the invention is tetraethyl-2-[3-t-butyl-4-hydroxynaphthyl]ethenylidene-1,1-diphosphonate.... | 04/20/1993 |
| 5137882 | Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibitors Invented are 3-acetic acid-steroidal compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-reductase including using these compounds to reduce prostate size and to treat prostatic... | 08/11/1992 |
